Publications by authors named "Cheuk-Him Man"

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SLC25A1 reprograms mitochondrial and fatty acid metabolism to promote the progression of acute myeloid leukemia.
Miao Chen, Wenze Li, Yuan Tao, Chenglong Hu, Rui Ge, Cheuk Him Man

Haematologica· September 2025

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Metabolic regulation in normal and leukemic stem cells.
Cheuk-Him Man, Changzheng Li, Xi Xu, Meng Zhao

Trends Pharmacol Sci· October 2024

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SUCLG1 restricts POLRMT succinylation to enhance mitochondrial biogenesis and leukemia progression.
Weiwei Yan, Chengmei Xie, Sijun Sun, Quan Zheng, Jingyi Wang, Cheuk-Him Man

EMBO J· June 2024

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Metabolism in Hematopoiesis and Its Malignancy.
Xiaoyuan Zeng, Yi-Ping Wang, Cheuk-Him Man

Adv Exp Med Biol· January 2024

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Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML.
Cheuk-Him Man, Wing Lam, Chee-Chean Dang, Xiao-Yuan Zeng, Li-Chuan Zheng, Natalie Nok-Man Chan

Blood· December 2023

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Loss of sphingosine kinase 2 promotes the expansion of hematopoietic stem cells by improving their metabolic fitness.
Changzheng Li, Binghuo Wu, Yishan Li, Yaxi Liu, Jin Wang, Cheuk Him Man

Blood· October 2022

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In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies.
Francois E Mercier, Jiantao Shi, David B Sykes, Toshihiko Oki, Maja Jankovic, Cheuk Him Man

Blood Adv· September 2022

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COVID-19 metabolism: Mechanisms and therapeutic targets.
Tianshi Wang, Ying Cao, Haiyan Zhang, Zihao Wang, Cheuk Him Man

MedComm (2020)· September 2022

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Regulation of proton partitioning in kinase-activating acute myeloid leukemia and its therapeutic implication.
Cheuk-Him Man, Xiaoyuan Zeng, Wing Lam, Timothy C C Ng, Tsz-Ho Kwok

Leukemia· August 2022

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Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth.
Cheuk Him Man, Francois E Mercier, Nian Liu, Wentao Dong, Gregory Stephanopoulos

Blood· January 2022

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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis.
Yi-Ping Wang, Azeem Sharda, Shuang-Nian Xu, Nick van Gastel, Cheuk Him Man

Cell Metab· May 2021

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Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia.
Bai-Liang He, Ning Yang, Cheuk Him Man, Nelson Ka-Lam Ng, Chae-Yin Cher

EMBO Mol Med· August 2020

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Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia.
Bai-Liang He, Ning Yang, Cheuk Him Man, Nelson Ka-Lam Ng, Chae-Yin Cher

EMBO Mol Med· April 2020

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Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia.
Stephen S Y Lam, Eric S K Ho, Bai-Liang He, Wui-Wing Wong, Chae-Yin Cher, Cheuk-Him Man

Sci Transl Med· October 2016

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Azacitidine as post-remission consolidation for sorafenib-induced remission of Fms-like tyrosine kinase-3 internal tandem duplication positive acute myeloid leukemia.
Harinder Gill, Cheuk-Him Man, Alvin H W Ip, William W L Choi, Howard C H Chow

Haematologica· July 2015

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Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia.
Cheuk Him Man, Tsz Kan Fung, Haixia Wan, Chae Yin Cher, August Fan

Blood· June 2015

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Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish.
Xiangguo Shi, Bai-Liang He, Alvin C H Ma, Yuhan Guo, Yali Chi, Cheuk Him Man

Blood· May 2015

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Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia.
Bai-Liang He, Xiangguo Shi, Cheuk Him Man, Alvin C H Ma, Stephen C Ekker

Blood· April 2014

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A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML.
Cheuk Him Man, Stephen S Y Lam, Murphy K H Sun, Howard C H Chow, Harinder Gill

Blood· April 2014

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Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.
Cheuk Him Man, Tsz Kan Fung, Christa Ho, Heron H C Han, Howard C H Chow

Blood· May 2012

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Inhibition of NOTCH3 signalling significantly enhances sensitivity to cisplatin in EBV-associated nasopharyngeal carcinoma.
Cheuk-Him Man, Samantha Wei-Man Lun, Jan Wai-Ying Hui, Ka-Fai To, Kwong-Wai Choy

J Pathol· February 2012

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