Publications by authors named "Chi-Ho To"

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Hypomethylation of thrombospondin-1 promoter region is associated with reduced aqueous humor flow.
Kit Ying Choy, Wei-Ying Yang, Choi-Ying Ling, King-Kit Li, Hoi Lam Li, Chi-Ho To

Commun Biol· October 2025

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Myopia control efficacy of second-generation defocus incorporated multiple segments spectacle lenses on fast progressing myopes: Study protocol of a randomised controlled trial.
Ying Hon, Rachel Ka Man Chun, Tsz Wing Leung, Hua Qi, Keigo Hasegawa, Chi Ho To

PLoS One· October 2025

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Effect of daily disposable Defocus Incorporated Soft Contact lens on myopia control: a 1-year multicentre randomised controlled trial.
Lin Liu, Jinghui Wang, Dennis Yan-Yin Tse, Bing Zuo, Desheng Song, Chi Ho To

Br J Ophthalmol· September 2025

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Bidirectional Phosphorylation Changes in Opsins Associated With Early Myopia and Hyperopia Signal Regulation by Phosphoproteomics.
Yang Yang, Ying Hon Sze, Houjiang Zhou, Winky Wing Man Ko, Yuanliang Zhang, Chi-Ho To

Invest Ophthalmol Vis Sci· July 2025

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Effectiveness of bright light therapy and combination with myopic defocus for controlling myopic eye growth in schoolchildren: study protocol for a randomised controlled trial (phase 1).
Ying Hon, Rachel Ka Man Chun, Billy Kin Kwok Cheung, Desmond Man Kit Lam, Andy Chi Wai Kong, Chi Ho To, Christopher Kai Shun Leung

BMJ Open Ophthalmol· May 2025

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Real-world outcomes of Defocus Incorporated Multiple Segments lenses on retarding axial elongation in myopic children and adolescents.
Rachel K M Chun, Kryshell Y Q Wong, Carly S Y Lam, Chi-Ho To, Kenneth K K Liu

Front Med (Lausanne)· January 2025

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Identification of Potential Growth-Related Proteins in Chick Vitreous during Emmetropization Using SWATH-MS and Targeted-Based Proteomics (MRMHR).
Jimmy Ka-Wai Cheung, King-Kit Li, Lei Zhou, Chi-Ho To, Thomas Chuen Lam

Int J Mol Sci· October 2024

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Combination effect of optical defocus and low dose atropine in myopia control: Study protocol for a randomized clinical trial.
Rachel Ka Man Chun, Ying Hon, Tsz Kin Law, Kryshell Yu Qi Wong, Chi Ho To, Christopher Kai Shun Leung

PLoS One· June 2024

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Defocus incorporated multiple segments (DIMS) spectacle lenses increase the choroidal thickness: a two-year randomized clinical trial.
Rachel Ka Man Chun, Hanyu Zhang, Zhengji Liu, Dennis Yan Yin Tse, Yongjin Zhou, Chi Ho To

Eye Vis (Lond)· September 2023

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Thinning of the Lamina Cribrosa and Deep Layer Microvascular Dropout in Patients With Open Angle Glaucoma and High Myopia.
Yanhui Chen, Baoyue Mi, Haoru Li, Bei Du, Lin Liu, Chi-Ho To

J Glaucoma· July 2023

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Differential Responses of Retinal Neurons and Glia Revealed via Proteomic Analysis on Primary and Secondary Retinal Ganglion Cell Degeneration.
Jacky M K Kwong, Joseph Caprioli, Joanne C Y Lee, Yifan Song, Feng-Juan Yu, Chi-Ho To

Int J Mol Sci· July 2023

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Changes in relative peripheral refraction in children who switched from single-vision lenses to Defocus Incorporated Multiple Segments lenses.
Han Yu Zhang, Carly Siu Yin Lam, Wing Chun Tang, Paul H Lee, Dennis Y Tse, Chi Ho To

Ophthalmic Physiol Opt· May 2023

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Additive effects of narrowband light and optical defocus on chick eye growth and refraction.
Rachel Ka-Man Chun, Kit-Ying Choy, King-Kit Li, Thomas Chuen Lam, Dennis Yan-Yin Tse, Chi-Ho To

Eye Vis (Lond)· April 2023

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Long-term myopia control effect and safety in children wearing DIMS spectacle lenses for 6 years.
Carly Siu Yin Lam, Wing Chun Tang, Han Yu Zhang, Paul H Lee, Dennis Yan Yin Tse, Chi Ho To

Sci Rep· April 2023

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Regulation of Aqueous Humor Secretion by Melatonin in Porcine Ciliary Epithelium.
Ka-Lok Li, Sze-Wan Shan, Fang-Yu Lin, Choi-Ying Ling, Nga-Wai Wong, Chi-Ho To

Int J Mol Sci· March 2023

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Mechanistic Effects of Baicalein on Aqueous Humor Drainage and Intraocular Pressure.
Hoi-Lam Li, Sze Wan Shan, W Daniel Stamer, King-Kit Li, Henry Ho-Lung Chan, Chi-Ho To

Int J Mol Sci· July 2022

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Transcriptional profiling of the chick retina identifies down-regulation of and genes during early lens-induced myopia.
Sze Wan Shan, Pan Feng Wang, Jimmy Ka Wai Cheung, Fengjuan Yu, Hui Zheng, Chi Ho To

Mol Omics· June 2022

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Retinal Proteomic Analysis in a Mouse Model of Endotoxin-Induced Uveitis Using Data-Independent Acquisition-Based Mass Spectrometry.
Jing Zhang, Jiangmei Wu, Daqian Lu, Chi-Ho To, Thomas Chuen Lam

Int J Mol Sci· June 2022

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Baicalein-A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury.
Li Pan, Ying Hon Sze, Menglu Yang, Jing Tang, Siming Zhao, Chi-Ho To

Front Immunol· May 2022

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Development pattern of ocular biometric parameters and refractive error in young Chinese adults: a longitudinal study of first-year university students.
Xue Bai, Nan Jin, Qingxin Wang, Yicheng Ge, Bei Du, Chi-Ho To

BMC Ophthalmol· May 2022

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Myopia Control Effect Is Influenced by Baseline Relative Peripheral Refraction in Children Wearing Defocus Incorporated Multiple Segments (DIMS) Spectacle Lenses.
Hanyu Zhang, Carly S Y Lam, Wing-Chun Tang, Myra Leung, Hua Qi, Chi-Ho To

J Clin Med· April 2022

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Evaluation of an Optical Defocus Treatment for Myopia Progression Among Schoolchildren During the COVID-19 Pandemic.
Kai Yip Choi, Rachel Ka Man Chun, Wing Chun Tang, Chi Ho To, Carly Siu-Yin Lam

JAMA Netw Open· January 2022

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Alteration of EIF2 Signaling, Glycolysis, and Dopamine Secretion in Form-Deprived Myopia in Response to 1% Atropine Treatment: Evidence From Interactive iTRAQ-MS and SWATH-MS Proteomics Using a Guinea Pig Model.
Ying Zhu, Jing Fang Bian, Da Qian Lu, Chi Ho To, Carly Siu-Yin Lam

Front Pharmacol· January 2022

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Baicalein, Baicalin, and Wogonin: Protective Effects against Ischemia-Induced Neurodegeneration in the Brain and Retina.
Li Pan, Kin-Sang Cho, Irvin Yi, Chi-Ho To, Dong Feng Chen

Oxid Med Cell Longev· December 2021

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Targeting Lysosomes to Reverse Hydroquinone-Induced Autophagy Defects and Oxidative Damage in Human Retinal Pigment Epithelial Cells.
Samuel Abokyi, Sze-Wan Shan, Christie Hang-I Lam, Kirk Patrick Catral, Feng Pan, Chi-Ho To

Int J Mol Sci· August 2021

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