Publications by authors named "Chiara Simone"

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Polystyrene microplastics are internalized by human gingival fibroblasts, enhance cell motility and induce molecular changes revealed through proteomic analysis.
Federica Di Cintio, Anna Giulia Ruggieri, Chiara De Simone, Piero Di Carlo, Maurizio Ronci

Sci Rep· October 2025

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SHP2 is a multifunctional target in anaplastic thyroid carcinoma: Cell intrinsic and immune-dependent anti-tumor effects.
Maria Marotta, Sara Zirpoli, Nella Prevete, Chiara De Simone, Antonio Di Cristofano

Biomed Pharmacother· September 2025

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Discovery and Evaluation of Novel Sulfonamide Derivatives Targeting Aromatase in ER+ Breast Cancer.
Barbara De Filippis, Mariangela Agamennone, Alessandra Ammazzalorso, Rosa Amoroso, Letizia Giampietro, Chiara De Simone

Pharmaceuticals (Basel)· August 2025

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Role of LIMK1-cofilin-actin axis in dendritic spine dynamics in Alzheimer's disease.
Fabiola Paciello, Martina Battistoni, Sara Martini, Chiara Simone, Francesco Pastore

Cell Death Dis· June 2025

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Formyl peptide receptor 1 signaling strength orchestrates the switch from pro-inflammatory to pro-resolving responses: The way to exert its anti-angiogenic and tumor suppressor functions.
Federica Liotti, Maria Marotta, Mattia Costanzo, Chiara De Simone, Sara Zirpoli

Biomed Pharmacother· May 2025

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Proteomics Studies on Extracellular Vesicles Derived from Glioblastoma: Where Do We Stand?
Patricia Giuliani, Chiara De Simone, Giorgia Febo, Alessia Bellasame, Nicola Tupone

Int J Mol Sci· September 2024

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Polymorphism Pro64His within galectin-3 has functional consequences at proteome level in thyroid cells.
Roberto Silvestri, Lorenzo Zallocco, Alda Corrado, Maurizio Ronci, Romina Aceto, Chiara De Simone

Front Genet· June 2024

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Neuroprotective and Antioxidant Role of Oxotremorine-M, a Non-selective Muscarinic Acetylcholine Receptors Agonist, in a Cellular Model of Alzheimer Disease.
Domenico Nuzzo, Monica Frinchi, Costanza Giardina, Miriana Scordino, Mariachiara Zuccarini, Chiara De Simone

Cell Mol Neurobiol· July 2023

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New amidine-benzenesulfonamides as iNOS inhibitors for the therapy of the triple negative breast cancer.
M Dora Carrión, Belén Rubio-Ruiz, Francisco Franco-Montalban, Pasquale Amoia, Maria Chiara Zuccarini, Chiara De Simone

Eur J Med Chem· February 2023

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Changes in quality of life and dyspnoea after hospitalization in COVID-19 patients discharged at home.
Pierachille Santus, Francesco Tursi, Giuseppe Croce, Chiara Di Simone, Francesca Frassanito

Multidiscip Respir Med· January 2020

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A case of Legionella pneumophila evaluated with CT and ultrasound.
Alessio D'Angelo, Chiara De Simone, Marco Pagnottella, Stefano Rossi, Raffaele Pepe

J Ultrasound· September 2017

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Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS.
Ilary Allodi, Laura Comley, Susanne Nichterwitz, Monica Nizzardo, Chiara Simone

Sci Rep· May 2016

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Is spinal muscular atrophy a disease of the motor neurons only: pathogenesis and therapeutic implications?
Chiara Simone, Agnese Ramirez, Monica Bucchia, Paola Rinchetti, Hardy Rideout

Cell Mol Life Sci· March 2016

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MFN2-related neuropathies: Clinical features, molecular pathogenesis and therapeutic perspectives.
Giulia Stuppia, Federica Rizzo, Giulietta Riboldi, Roberto Del Bo, Monica Nizzardo, Chiara Simone

J Neurol Sci· September 2015

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Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches.
Monica Nizzardo, Chiara Simone, Sara Dametti, Sabrina Salani, Gianna Ulzi

Sci Rep· June 2015

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Therapeutic development in amyotrophic lateral sclerosis.
Monica Bucchia, Agnese Ramirez, Valeria Parente, Chiara Simone, Monica Nizzardo

Clin Ther· March 2015

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Gene therapy rescues disease phenotype in a spinal muscular atrophy with respiratory distress type 1 (SMARD1) mouse model.
Monica Nizzardo, Chiara Simone, Federica Rizzo, Sabrina Salani, Sara Dametti

Sci Adv· March 2015

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Pluripotent stem cell-based models of spinal muscular atrophy.
Emanuele Frattini, Margherita Ruggieri, Sabrina Salani, Irene Faravelli, Chiara Zanetta, Chiara Simone

Mol Cell Neurosci· January 2015

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Antisense oligonucleotide therapy for the treatment of C9ORF72 ALS/FTD diseases.
Giulietta Riboldi, Chiara Zanetta, Michela Ranieri, Monica Nizzardo, Chiara Simone

Mol Neurobiol· December 2014

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The wide spectrum of clinical phenotypes of spinal muscular atrophy with respiratory distress type 1: a systematic review.
Francesca Porro, Paola Rinchetti, Francesca Magri, Giulietta Riboldi, Monica Nizzardo, Chiara Simone

J Neurol Sci· November 2014

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Stem cell transplantation for amyotrophic lateral sclerosis: therapeutic potential and perspectives on clinical translation.
Irene Faravelli, Giulietta Riboldi, Monica Nizzardo, Chiara Simone, Chiara Zanetta

Cell Mol Life Sci· September 2014

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iPSC-Derived neural stem cells act via kinase inhibition to exert neuroprotective effects in spinal muscular atrophy with respiratory distress type 1.
Chiara Simone, Monica Nizzardo, Federica Rizzo, Margherita Ruggieri, Giulietta Riboldi

Stem Cell Reports· August 2014

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Motor neuron derivation from human embryonic and induced pluripotent stem cells: experimental approaches and clinical perspectives.
Irene Faravelli, Monica Bucchia, Paola Rinchetti, Monica Nizzardo, Chiara Simone

Stem Cell Res Ther· July 2014

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Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype.
Monica Nizzardo, Chiara Simone, Sabrina Salani, Marc-David Ruepp, Federica Rizzo

Clin Ther· March 2014

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Molecular, genetic and stem cell-mediated therapeutic strategies for spinal muscular atrophy (SMA).
Chiara Zanetta, Giulietta Riboldi, Monica Nizzardo, Chiara Simone, Irene Faravelli

J Cell Mol Med· February 2014

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