Publications by authors named "Chidiebere Awah"

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In vivo inhibition of c-MYC in the metastatic drug-resistant ovarian cancer cells down regulates the c-MYC-PD-L1-PAX8-p21 to achieve therapeutic efficacy.
Queenie Chen, Jigme P Dorji, Sandali G Perera, Petvy Li, Fizza Aijaz, Chidiebere U Awah

BMC Cancer· December 2025

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c-MYC mRNA destabilization inhibited lethal pancreatic cancer with significant survival outcomes.
Jigme P Dorji, Queenie Chen, Sandali G Perera, Fizza Aijaz, Petvy Li, Chidiebere U Awah

Front Pharmacol· September 2025

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The Engineered Drug 3'UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer.
Chidiebere U Awah, Joo Sun Mun, Aloka Paragodaarachchi, Baris Boylu, Chika Ochu

Cancers (Basel)· July 2024

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Nanocage-incorporated engineered destabilized 3'UTR ARE of ERBB2 inhibits tumor growth and liver and lung metastasis in EGFR T790M osimertinib- and trastuzumab-resistant and ERBB2-expressing NSCLC via the reduction of ERBB2.
Chidiebere U Awah, Joo Sun Mun, Aloka Paragodaarachchi, Baris Boylu, Martin Nzegwu

Front Oncol· April 2024

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Destabilized 3'UTR elements therapeutically degrade ERBB2 mRNA in drug-resistant ERBB2+ cancer models.
Chidiebere U Awah, Yana Glemaud, Fayola Levine, Kiseok Yang, Afrin Ansary

Front Genet· June 2023

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Genome scale CRISPR Cas9a knockout screen reveals genes that control glioblastoma susceptibility to the alkylating agent temozolomide.
Chidiebere U Awah, Jan Winter, Olorunseun O Ogunwobi

All Life· January 2022

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NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction.
Chidiebere U Awah, Jan Winter, Claudiane M Mazdoom, Olorunseun O Ogunwobi

Cancer Biol Ther· December 2021

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Therapeutic Targeting of Exportin-1 in Childhood Cancer.
Basia Galinski, Thomas B Alexander, Daniel A Mitchell, Hannah V Chatwin, Chidiebere Awah

Cancers (Basel)· December 2021

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Ribosomal protein S11 influences glioma response to TOP2 poisons.
Chidiebere U Awah, Li Chen, Mukesh Bansal, Aayushi Mahajan, Jan Winter

Oncogene· July 2020

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Topoisomerase II Poisons for Glioblastoma; Existing Challenges and Opportunities to Personalize Therapy.
Amol Mehta, Chidiebere U Awah, Adam M Sonabend

Front Neurol· June 2018

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Mechanism of allele specific assembly and disruption of master regulator transcription factor complexes of NF-KBp50, NF-KBp65 and HIF1a on a non-coding FAS SNP.
Chidiebere U Awah, Stephanie Tamm, Silke Hedtfeld, Doris Steinemann, Burkhard Tümmler

Biochim Biophys Acta· November 2016

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Promiscuous partnering and independent activity of MexB, the multidrug transporter protein from Pseudomonas aeruginosa.
Alexander Welch, Chidiebere U Awah, Shiheng Jing, Hendrik W van Veen, Henrietta Venter

Biochem J· September 2010

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