Publications by authors named "Chikashi Obuse"

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Regulated TRESLIN-MTBP loading governs initiation zones and replication timing in human DNA replication.
Xiaoxuan Zhu, Atabek Bektash, Yuki Hatoyama, Sachiko Muramatsu, Shin-Ya Isobe, Chikashi Obuse

Nat Commun· December 2025

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scRepli-RamDA-seq: a multi-omics technology enabling the analysis of gene expression dynamics during S-phase.
Rawin Poonperm, Taiki Yoneda, Taito Imada, Saori Takahashi, Takako Ichinose, Chikashi Obuse

Nat Commun· December 2025

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Functional involvement of RNAs and intrinsically disordered proteins in the assembly of heterochromatin.
Chikashi Obuse, Jun-Ichi Nakayama

Biochim Biophys Acta Gen Subj· May 2025

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Interaction mapping between nucleoporins in the fission yeast Schizosaccharomyces pombe using mass-spectrometry.
Haruhiko Asakawa, Koji Nagao, Tatsuo Fukagawa, Chikashi Obuse, Yasushi Hiraoka

J Biochem· April 2025

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Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46.
Yutaka Mahana, Mariko Ariyoshi, Ryu-Suke Nozawa, Sachiko Shibata, Koji Nagao, Chikashi Obuse

Structure· March 2024

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Functional domains of nuclear long noncoding RNAs: Insights into gene regulation and intracellular architecture.
Chikashi Obuse, Tetsuro Hirose

Curr Opin Cell Biol· December 2023

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Replication dynamics identifies the folding principles of the inactive X chromosome.
Rawin Poonperm, Saya Ichihara, Hisashi Miura, Akie Tanigawa, Koji Nagao, Chikashi Obuse

Nat Struct Mol Biol· August 2023

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Dominant-negative variants in CBX1 cause a neurodevelopmental disorder.
Yukiko Kuroda, Aiko Iwata-Otsubo, Kerith-Rae Dias, Suzanna E L Temple, Koji Nagao, Chikashi Obuse

Genet Med· July 2023

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Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast.
Yasuhiro Hirano, Yasuha Kinugasa, Yoshino Kubota, Chikashi Obuse, Tokuko Haraguchi

J Biochem· June 2023

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Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages.
Osamu Masui, Catherine Corbel, Koji Nagao, Takaho A Endo, Fuyuko Kezuka, Chikashi Obuse

Nat Cell Biol· January 2023

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RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells.
Sho Sugawara, Ryo Okada, Tze Mun Loo, Hisamichi Tanaka, Kenichi Miyata, Chikashi Obuse

Commun Biol· December 2022

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SmcHD1 underlies the formation of H3K9me3 blocks on the inactive X chromosome in mice.
Saya Ichihara, Koji Nagao, Takehisa Sakaguchi, Chikashi Obuse, Takashi Sado

Development· August 2022

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Chromatin loading of MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry.
Yoko Hayashi-Takanaka, Yuichiro Hayashi, Yasuhiro Hirano, Atsuko Miyawaki-Kuwakado, Yasuyuki Ohkawa, Chikashi Obuse

Nucleic Acids Res· December 2021

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Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action.
Shin-Ya Isobe, Shin-Ichiro Hiraga, Koji Nagao, Hiroyuki Sasanuma, Anne D Donaldson, Chikashi Obuse

Cell Rep· July 2021

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Mapping replication timing domains genome wide in single mammalian cells with single-cell DNA replication sequencing.
Hisashi Miura, Saori Takahashi, Takahiro Shibata, Koji Nagao, Chikashi Obuse

Nat Protoc· December 2020

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Regulation of an adaptor protein STING by Hsp90β to enhance innate immune responses against microbial infections.
Seiichi Sato, Kai Li, Nozomi Sakurai, Mei Hashizume, Sunanda Baidya, Chikashi Obuse

Cell Immunol· October 2020

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Rare variant of the epigenetic regulator SMCHD1 in a patient with pituitary hormone deficiency.
Kenichi Kinjo, Keisuke Nagasaki, Koji Muroya, Erina Suzuki, Keisuke Ishiwata, Chikashi Obuse

Sci Rep· July 2020

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Subacute cutaneous lupus erythematosus with melanocyte elimination induced by pembrolizumab.
Mariko Ogawa-Momohara, Yoshinao Muro, Katsunobu Goto, Chikashi Obuse, Minoru Satoh

J Dermatol· June 2020

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Homozygous nonsense variant in associated with facioscapulohumeral muscular dystrophy.
Kohei Hamanaka, Darina Šikrová, Satomi Mitsuhashi, Hiroki Masuda, Yukari Sekiguchi, Chikashi Obuse

Neurology· June 2020

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KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells.
Kengo Okamoto, Yuji Tanaka, Sachiko Ogasawara, Chikashi Obuse, Jun-Ichi Nakayama

Oncotarget· July 2019

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Asymmetrical localization of Nup107-160 subcomplex components within the nuclear pore complex in fission yeast.
Haruhiko Asakawa, Tomoko Kojidani, Hui-Ju Yang, Chizuru Ohtsuki, Hiroko Osakada, Chikashi Obuse

PLoS Genet· June 2019

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Genome-wide stability of the DNA replication program in single mammalian cells.
Saori Takahashi, Hisashi Miura, Takahiro Shibata, Koji Nagao, Katsuzumi Okumura, Chikashi Obuse

Nat Genet· March 2019

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Publisher Correction: Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.
Akiko Takahashi, Ryo Okada, Koji Nagao, Yuka Kawamata, Aki Hanyu, Chikashi Obuse

Nat Commun· October 2018

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Role of SmcHD1 in establishment of epigenetic states required for the maintenance of the X-inactivated state in mice.
Yuki Sakakibara, Koji Nagao, Marnie Blewitt, Hiroyuki Sasaki, Chikashi Obuse

Development· September 2018

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Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1.
Riki Terui, Koji Nagao, Yoshitaka Kawasoe, Kanae Taki, Torahiko L Higashi, Chikashi Obuse

Genes Dev· June 2018

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