Publications by authors named "Ching On Wong"

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Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes.
Jagannatham Naidu Bhupana, Angelid Pabon, Ho Hang Leung, Mohamed Asik Rajmohamed, Sang Hoon Kim, Ching-On Wong

Nat Commun· May 2025

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Crosstalk between degradation and bioenergetics: how autophagy and endolysosomal processes regulate energy production.
Angelid Pabon, Jagannatham Naidu Bhupana, Ching-On Wong

Neural Regen Res· March 2025

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Drosophila tweety facilitates autophagy to regulate mitochondrial homeostasis and bioenergetics in Glia.
Ho Hang Leung, Christina Mansour, Morgan Rousseau, Anwar Nakhla, Kirill Kiselyov, Ching-On Wong

Glia· February 2024

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Human Prune Regulates the Metabolism of Mammalian Inorganic Polyphosphate and Bioenergetics.
Ernest R Scoma, Renata T Da Costa, Ho Hang Leung, Pedro Urquiza, Mariona Guitart-Mampel, Ching-On Wong

Int J Mol Sci· September 2023

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Loss of Activity-Induced Mitochondrial ATP Production Underlies the Synaptic Defects in a Model of ALS.
Nicholas E Karagas, Richa Gupta, Elham Rastegari, Kai Li Tan, Ho Hang Leung, Ching-On Wong

J Neurosci· October 2022

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Low doses of the organic insecticide spinosad trigger lysosomal defects, elevated ROS, lipid dysregulation, and neurodegeneration in flies.
Felipe Martelli, Natalia H Hernandes, Zhongyuan Zuo, Julia Wang, Ching-On Wong

Elife· February 2022

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Regulation of longevity by depolarization-induced activation of PLC-β-IPR signaling in neurons.
Ching-On Wong, Nicholas E Karagas, Jewon Jung, Qiaochu Wang, Morgan A Rousseau

Proc Natl Acad Sci U S A· April 2021

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Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in .
Felipe Martelli, Zuo Zhongyuan, Julia Wang, Ching-On Wong, Nicholas E Karagas

Proc Natl Acad Sci U S A· October 2020

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Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes.
Ching-On Wong

Int J Mol Sci· July 2020

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Motor neurons from ALS patients with mutations in C9ORF72 and SOD1 exhibit distinct transcriptional landscapes.
Ching-On Wong, Kartik Venkatachalam

Hum Mol Genet· August 2019

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HRAS-driven cancer cells are vulnerable to TRPML1 inhibition.
Jewon Jung, Kwang-Jin Cho, Ali K Naji, Kristen N Clemons, Ching On Wong

EMBO Rep· April 2019

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Author Correction: TRPC5 channels participate in pressure-sensing in aortic baroreceptors.
On-Chai Lau, Bing Shen, Ching-On Wong, Yung-Wui Tjong, Chun-Yin Lo

Nat Commun· March 2018

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Correspondence: Reply to 'Challenging a proposed role for TRPC5 in aortic baroreceptor pressure-sensing'.
On-Chai Lau, Bing Shen, Ching-On Wong, Xiaoqiang Yao

Nat Commun· March 2018

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Lysosomal Degradation Is Required for Sustained Phagocytosis of Bacteria by Macrophages.
Ching-On Wong, Steven Gregory, Hongxiang Hu, Yufang Chao, Victoria E Sepúlveda

Cell Host Microbe· June 2017

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TRPC5 channels participate in pressure-sensing in aortic baroreceptors.
On-Chai Lau, Bing Shen, Ching-On Wong, Yung-Wui Tjong, Chun-Yin Lo

Nat Commun· July 2016

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Plasma membrane mechanical stress activates TRPC5 channels.
Bing Shen, Ching-On Wong, On-Chai Lau, Theodosia Woo, Suwen Bai

PLoS One· December 2015

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Diminished MTORC1-Dependent JNK Activation Underlies the Neurodevelopmental Defects Associated with Lysosomal Dysfunction.
Ching-On Wong, Michela Palmieri, Jiaxing Li, Dmitry Akhmedov, Yufang Chao

Cell Rep· September 2015

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SIGNAL TRANSDUCTION. Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling.
Yong Zhou, Ching-On Wong, Kwang-jin Cho, Dharini van der Hoeven, Hong Liang

Science· August 2015

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The role of TRPMLs in endolysosomal trafficking and function.
Kartik Venkatachalam, Ching-On Wong, Michael X Zhu

Cell Calcium· July 2015

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A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission.
Ching-On Wong, Kuchuan Chen, Yong Qi Lin, Yufang Chao, Lita Duraine

Neuron· November 2014

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Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane.
Xinghua Feng, Yu Huang, Yungang Lu, Jian Xiong, Ching-On Wong

J Biol Chem· February 2014

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Feast or famine: role of TRPML in preventing cellular amino acid starvation.
Kartik Venkatachalam, Ching-On Wong, Craig Montell

Autophagy· January 2013

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Drosophila TRPML is required for TORC1 activation.
Ching-On Wong, Ruoxia Li, Craig Montell, Kartik Venkatachalam

Curr Biol· September 2012

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Structural basis for GTP-dependent dimerization of hydrogenase maturation factor HypB.
Kwok-Ho Chan, Ting Li, Ching-On Wong, Kam-Bo Wong

PLoS One· June 2012

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Heteromeric TRPV4-C1 channels contribute to store-operated Ca(2+) entry in vascular endothelial cells.
Xin Ma, Kwong-Tai Cheng, Ching-On Wong, Roger G O'Neil, Lutz Birnbaumer

Cell Calcium· December 2011

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