Publications by authors named "Ching-Seng Ang"

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Early-life social isolation stress worsens compulsive- and anxiety-like behaviour and alters gene expression in the prefrontal cortex of SAPAP3 knockout mice.
Carey Wilson, James J Gattuso, Maria Kuznetsova, Shanshan Li, Ching-Seng Ang

J Affect Disord· November 2025

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Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia.
Alexander C Lewis, Emily Gruber, Rheana Franich, Jessica Armstrong, Madison J Kelly, Ching-Seng Ang

Cell· November 2025

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Comparative proteomic analysis of Porphyromonas gingivalis challenged human dental pulp stem cells.
Sze Wei Liu, Ching-Seng Ang, Rita Paolini, Rachael L Moses, Alastair J Sloan

Sci Rep· November 2025

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Targeting PAK1 or PAK4 Uncovers Different Mechanisms of Vascular Reprogramming in Pancreatic Cancer.
Arian Ansardamavandi, Chelsea Dumesny, Sarah Ellis, Ching-Seng Ang, Mehrdad Nikfarjam

Cells· November 2025

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Evaluation of Nanoparticle-Based Plasma Enrichment on Individuals with Primary and Metastatic Pancreatic Cancer.
Ching-Seng Ang, Nicholas A Williamson, Chelsea Dumesny, Michael G Leeming, Keshava Datta

Cancers (Basel)· November 2025

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Amniotic Fluid Extracellular Vesicle Properties Evolve With Gestational Age and Reflect Fetal Development.
Ishara Atukorala, Sally Beard, Ching-Seng Ang, Hamish Brown, Swetha Raghavan

J Extracell Biol· October 2025

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The formation of the 'footprint of death' as a mechanism for generating large substrate-bound extracellular vesicles that mark the site of cell death.
Stephanie F Rutter, Taeyoung Kang, Gemma F Ryan, Bo Shi, Caitlin L Vella, Ching-Seng Ang

Nat Commun· October 2025

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Conformational dynamics, RNA binding, and phase separation regulate the multifunctionality of rabies virus P protein.
Stephen M Rawlinson, Shatabdi Chakraborty, Ashish Sethi, Cassandra T David, Angela R Harrison, Ching-Seng Ang

Nat Commun· October 2025

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The Effects of PAK-Regulated Tumour Vasculature on Gemcitabine Response of Pancreatic Cancer.
Arian Ansardamavandi, Chelsea Dumesny, Yi Ma, Li Dong, Sarah Ellis, Ching-Seng Ang

Cancers (Basel)· October 2025

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Comprehensive developmental somatic proteome atlas of Haemonchus contortus underpinned by a chromosome-scale genome and deep tandem mass spectrometry.
Tao Wang, Yuanting Zheng, Neil D Young, Ching-Seng Ang, Robin B Gasser

Parasit Vectors· September 2025

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P-21 Kinase 1 or 4 Knockout Stimulated Anti-Tumour Immunity Against Pancreatic Cancer by Enhancing Vascular Normalisation.
Arian Ansardamavandi, Chelsea Dumesny, Yi Ma, Li Dong, Sarah Ellis, Ching-Seng Ang

Int J Mol Sci· August 2025

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Structural dynamics of IDR interactions in human SFPQ and implications for liquid-liquid phase separation.
Heidar J Koning, Valerie Lai, Ashish Sethi, Shatabdi Chakraborty, Ching Seng Ang

Acta Crystallogr D Struct Biol· July 2025

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MORC2 is a phosphorylation-dependent DNA compaction machine.
Winnie Tan, Jeongveen Park, Hariprasad Venugopal, Jieqiong Lou, Prabavi Shayana Dias, Ching-Seng Ang

Nat Commun· July 2025

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Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins.
Kai-Qi Yek, Evie R Hodgson, Ching-Seng Ang, Catherine S Palmer, Ann E Frazier

PLoS Biol· July 2025

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Knockout of p21-Activated Kinase 4 Stimulates MHC I Expression of Pancreatic Cancer Cells via an Autophagy-Independent Pathway.
Yi Ma, Chelsea Dumesny, Li Dong, Ching-Seng Ang, Mehrdad Nikfarjam

Cancers (Basel)· February 2025

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MR1 presents vitamin B6-related compounds for recognition by MR1-reactive T cells.
Mitchell P McInerney, Wael Awad, Michael N T Souter, Yang Kang, Carl J H Wang, Ching-Seng Ang

Proc Natl Acad Sci U S A· December 2024

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A micro-costing study of mass-spectrometry based quantitative proteomics testing applied to the diagnostic pipeline of mitochondrial and other rare disorders.
Francisco Santos Gonzalez, Daniella H Hock, David R Thorburn, Dylan Mordaunt, Nicholas A Williamson, Ching-Seng Ang

Orphanet J Rare Dis· November 2024

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Correction: Novel CDKL5 targets identified in human iPSC-derived neurons.
Sean Massey, Ching-Seng Ang, Nadia M Davidson, Anita Quigley, Ben Rollo

Cell Mol Life Sci· September 2024

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Comparative structure activity and target exploration of 1,2-diphenylethynes in Haemonchus contortus and Caenorhabditis elegans.
Harrison T Shanley, Aya C Taki, Nghi Nguyen, Tao Wang, Joseph J Byrne, Ching-Seng Ang, Bill C H Chang

Int J Parasitol Drugs Drug Resist· August 2024

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Novel CDKL5 targets identified in human iPSC-derived neurons.
Sean Massey, Ching-Seng Ang, Nadia M Davidson, Anita Quigley, Ben Rollo

Cell Mol Life Sci· August 2024

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Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription.
Charles C Bell, Jesse J Balic, Laure Talarmain, Andrea Gillespie, Laura Scolamiero, Ching-Seng Ang

Nat Genet· June 2024

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MORC2 phosphorylation fine tunes its DNA compaction activity.
Winnie Tan, Jeong Veen Park, Hariprasad Venugopal, Jie Qiong Lou, Prabavi Shayana Dias, Ching-Seng Ang

bioRxiv· June 2024

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Inhibition of P21-activated kinases 1 and 4 synergistically suppresses the growth of pancreatic cancer by stimulating anti-tumour immunity.
Yi Ma, Chelsea Dumesny, Li Dong, Ching-Seng Ang, Khashayar Asadi

Cell Commun Signal· May 2024

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Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity.
Harrison T Shanley, Aya C Taki, Nghi Nguyen, Tao Wang, Joseph J Byrne, Ching-Seng Ang, Bill C H Chang

Int J Parasitol Drugs Drug Resist· April 2024

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Targeting the ribosome to treat multiple myeloma.
Kylee H Maclachlan, Kezia Gitareja, Jian Kang, Andrew Cuddihy, Yuxi Cao, Ching-Seng Ang

Mol Ther Oncol· March 2024

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