Publications by authors named "Ching-Ti Liu"

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Small Dense Low-Density Lipoprotein Cholesterol Is the Most Atherogenic Lipoprotein Parameter in the Prospective Framingham Offspring Study.
Hiroaki Ikezaki, Elise Lim, L Adrienne Cupples, Ching-Ti Liu, Bela F Asztalos, Ernst J Schaefer

J Am Heart Assoc· February 2021

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Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants.
Raymond Noordam, Wenyi Wang, Pavithra Nagarajan, Heming Wang, Michael R Brown, Ching-Ti Liu

Atherosclerosis· January 2026

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Evaluation of Sex-Stratified Polygenic Risk Scores for Type 2 Diabetes Mellitus and Glycemic Traits in the Framingham Heart Study.
Ningyuan Wang, Yixin Zhang, Philip Schroeder, Alicia Huerta-Chagoya, Ravi Mandla, Ching-Ti Liu

Diabetes Metab J· December 2025

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Integrating genetic and transcriptomic data to identify genes underlying obesity risk loci.
Hanfei Xu, Shreyash Gupta, Ian Dinsmore, Abbey Kollu, Anne Marie Cawley, Ching-Ti Liu

Int J Obes (Lond)· November 2025

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Physical Activity by Accelerometer Inversely Associated With Liver Fibrosis; Cross-Sectional Analysis of a Longitudinal Cohort.
Madeleine G Haff, Joanne M Murabito, Ramachandran S Vasan, Nicole L Spartano, Ching-Ti Liu

Liver Int· November 2025

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Dissecting Genetic and Environmental Determinants of Plasma Molecular Signatures and Their Link to Type 2 Diabetes Risk.
Magdalena Sevilla-González, Ningyuan Wang, Paul A Hanson, Allison Bebo, Daniel Hitchcock, Ching-Ti Liu

medRxiv· November 2025

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Ten-year dietary trends and urban-rural disparities in fruit, vegetable, meat, egg, and milk products consumption among older Chinese adults.
Cai Xu, Trishnee Bhurosy, Ching-Ti Liu, Yen-Han Lee

Nutr Diet· October 2025

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Robust Mixed Model Association Test for Gene-Environment Interactions.
Mengyu Zhang, Jingxian Tang, Michael R Brown, Alanna C Morrison, Eric Boerwinkle, Ching-Ti Liu

medRxiv· October 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Liubov Arbeeva, Jun Liu, Xueping Liu, Ching-Ti Liu, Jianjun Liu

Nat Med· September 2025

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Genome-wide association study provides novel insight into the genetic architecture of severe obesity.
Mohanraj Krishnan, Mohammad Yaser Anwar, Anne E Justice, Geetha Chittoor, Hung-Hsin Chen, Shuwei Liu, Ching-Ti Liu

PLoS Genet· September 2025

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A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations.
Pavithra Nagarajan, Thomas W Winkler, Amy R Bentley, Clint L Miller, Aldi T Kraja, Peter Y Liu, Ching-Ti Liu

Mol Psychiatry· August 2025

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Learning Gaussian Graphical Models from Correlated Data.
Zeyuan Song, Sophia Gunn, Stefano Monti, Gina Marie Peloso, Ching-Ti Liu

Front Syst Biol· July 2025

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Lipoprotein(a) and Heart Failure Among Black and White Participants in Atherosclerosis Risk in Communities Study, Framingham Offspring Study, and Multi-Ethnic Study of Atherosclerosis: The Pooling Project.
Sarah Nomura, Weihua Guan, Yixin Zhang, Geoffrey H Tison, Hiroaki Ikezaki, Ching-Ti Liu

J Am Heart Assoc· June 2025

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Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids.
Amy R Bentley, Michael R Brown, Solomon K Musani, Karen L Schwander, Thomas W Winkler, Yongmei Liu, Jianjun Liu, Ching-Ti Liu

Transl Psychiatry· June 2025

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Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Ching-Ti Liu

Nat Commun· April 2025

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Lipoprotein(a) and Risk of Incident Atherosclerotic Cardiovascular Disease: Impact of High-Sensitivity C-Reactive Protein and Risk Variability Among Human Clinical Subgroups.
Ron C Hoogeveen, Margaret R Diffenderfer, Elise Lim, Ching-Ti Liu, Hiroaki Ikezaki

Nutrients· April 2025

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Multi-ancestry whole genome sequencing analysis of lean body mass.
Xiaoyu Zhang, Kuan-Jui Su, Bodhisattwa Banerjee, Ittai Eres, Yi-Hsiang Hsu, Hanhan Liu, Ching-Ti Liu

Genome Biol· April 2025

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Heterogeneous effects of genetic variants and traits associated with fasting insulin on cardiometabolic outcomes.
Magdalena Sevilla-González, Kirk Smith, Ningyuan Wang, Aubrey E Jensen, Elizabeth M Litkowski, Ching-Ti Liu

Nat Commun· March 2025

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Diabetes Mellitus Risk Prediction in the Framingham Offspring Study and Large Population Analysis.
Masumi Ai, Seiko Otokozawa, Ching-Ti Liu, Bela F Asztalos, Julia Maddalena

Nutrients· March 2025

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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.
Xihao Li, Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, Hufeng Zhou, Ching-Ti Liu, Zhonghua Liu

Nat Comput Sci· February 2025

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A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations.
Songmi Lee, Clint L Miller, Amy R Bentley, Michael R Brown, Pavithra Nagarajan, Ching-Ti Liu

Res Sq· February 2025

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Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed.
Peter Orchard, Thomas W Blackwell, Linda Kachuri, Peter J Castaldi, Michael H Cho, Ching-Ti Liu, Yongmei Liu

medRxiv· February 2025

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Hepatic Steatosis and Fibrosis, Cardiorespiratory Fitness, and Metabolic Mediators in the Community.
Victor V Florea, Priya Gajjar, Shi Huang, Jingxian Tang, Shilin Zhao, Ching-Ti Liu

Liver Int· January 2025

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Machine learning-based clustering identifies obesity subgroups with differential multi-omics profiles and metabolic patterns.
Mohammad Y Anwar, Heather Highland, Victoria Lynn Buchanan, Mariaelisa Graff, Kristin Young, Yongmei Liu, Ching-Ti Liu

Obesity (Silver Spring)· November 2024

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Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.
Gareth Hawkes, Robin N Beaumont, Zilin Li, Ravi Mandla, Xihao Li, Ching-Ti Liu

Nat Commun· October 2024

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A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances.
Raymond Noordam, Wenyi Wang, Pavithra Nagarajan, Heming Wang, Michael R Brown, Ching-Ti Liu

medRxiv· September 2024

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