Publications by authors named "Chingakham Ranjit Singh"

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Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.
Eiji Obayashi, Rafael E Luna, Takashi Nagata, Pilar Martin-Marcos, Hiroyuki Hiraishi, Chingakham Ranjit Singh

Cell Rep· June 2024

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Mass spectrometry analysis of affinity-purified cytoplasmic translation initiation complexes from human and fly cells.
Chingakham Ranjit Singh, Naoki Tani, Akira Nakamura, Katsura Asano

STAR Protoc· December 2022

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Label-free protocol to quantify protein affinity using isothermal titration calorimetry and bio-layer interferometry of a human eIF5-mimic protein.
Chingakham Ranjit Singh, Rahul Jaiswal, Carlos R Escalante, Katsura Asano

STAR Protoc· September 2022

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Translational recoding by chemical modification of non-AUG start codon ribonucleotide bases.
Yoshihiko Fujita, Takeru Kameda, Chingakham Ranjit Singh, Whitney Pepper, Ariana Cecil

Sci Adv· April 2022

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Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism.
Chingakham Ranjit Singh, M Rebecca Glineburg, Chelsea Moore, Naoki Tani, Rahul Jaiswal

Cell Rep· July 2021

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Gcn2 eIF2α kinase mediates combinatorial translational regulation through nucleotide motifs and uORFs in target mRNAs.
Yuji Chikashige, Hiroaki Kato, Mackenzie Thornton, Whitney Pepper, Madelyn Hilgers, Chingakham Ranjit Singh

Nucleic Acids Res· September 2020

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The Interaction between the Ribosomal Stalk Proteins and Translation Initiation Factor 5B Promotes Translation Initiation.
Ryo Murakami, Chingakham Ranjit Singh, Jacob Morris, Leiming Tang, Ian Harmon

Mol Cell Biol· August 2018

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Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide.
Leiming Tang, Jacob Morris, Ji Wan, Chelsea Moore, Yoshihiko Fujita, Chingakham Ranjit Singh

Nucleic Acids Res· November 2017

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Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.
Eiji Obayashi, Rafael E Luna, Takashi Nagata, Pilar Martin-Marcos, Hiroyuki Hiraishi, Chingakham Ranjit Singh

Cell Rep· March 2017

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Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation.
Caitlin Kozel, Brytteny Thompson, Samantha Hustak, Chelsea Moore, Akio Nakashima, Chingakham Ranjit Singh

Nucleic Acids Res· October 2016

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Random mutagenesis of yeast 25S rRNA identify bases critical for 60S subunit structural integrity and function.
Naoki Nemoto, Tsuyoshi Udagawa, Wasimul Chowdhury, Makoto Kitabatake, Byung-Shik Shin, Chingakham Ranjit Singh

Translation (Austin)· January 2016

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Mechanisms by which synthetic 6,7-annulated-4-substituted indole compounds with anti-proliferative activity disrupt mitosis and block cytokinesis in human HL-60 tumor cells in vitro.
Jean-Pierre H Perchellet, Elisabeth M Perchellet, Chingakham Ranjit Singh, Meghan T Monnett, Elizabeth R Studer

Anticancer Res· April 2014

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The proteasome-associated protein Ecm29 inhibits proteasomal ATPase activity and in vivo protein degradation by the proteasome.
Alina De La Mota-Peynado, Stella Yu-Chien Lee, Brianne Marie Pierce, Prashant Wani, Chingakham Ranjit Singh

J Biol Chem· October 2013

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Reconfiguration of the proteasome during chaperone-mediated assembly.
Soyeon Park, Xueming Li, Ho Min Kim, Chingakham Ranjit Singh, Geng Tian

Nature· May 2013

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Sequential eukaryotic translation initiation factor 5 (eIF5) binding to the charged disordered segments of eIF4G and eIF2β stabilizes the 48S preinitiation complex and promotes its shift to the initiation mode.
Chingakham Ranjit Singh, Ryosuke Watanabe, Wasimul Chowdhury, Hiroyuki Hiraishi, Marcelo J Murai

Mol Cell Biol· October 2012

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Mechanisms of translational regulation by a human eIF5-mimic protein.
Chingakham Ranjit Singh, Ryosuke Watanabe, Donghui Zhou, Martin D Jennings, Akira Fukao

Nucleic Acids Res· October 2011

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Yeast 18 S rRNA is directly involved in the ribosomal response to stringent AUG selection during translation initiation.
Naoki Nemoto, Chingakham Ranjit Singh, Tsuyoshi Udagawa, Suzhi Wang, Elizabeth Thorson

J Biol Chem· October 2010

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The eukaryotic initiation factor (eIF) 4G HEAT domain promotes translation re-initiation in yeast both dependent on and independent of eIF4A mRNA helicase.
Ryosuke Watanabe, Marcelo Jun Murai, Chingakham Ranjit Singh, Stephanie Fox, Miki Ii

J Biol Chem· July 2010

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Eukaryotic initiation factor (eIF) 1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection.
Mikhail Reibarkh, Yasufumi Yamamoto, Chingakham Ranjit Singh, Federico del Rio, Amr Fahmy

J Biol Chem· January 2008

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Yeast phenotypic assays on translational control.
Bumjun Lee, Tsuyoshi Udagawa, Chingakham Ranjit Singh, Katsura Asano

Methods Enzymol· December 2007

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Localization and characterization of protein-protein interaction sites.
Chingakham Ranjit Singh, Katsura Asano

Methods Enzymol· December 2007

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Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo.
Chingakham Ranjit Singh, Tsuyoshi Udagawa, Bumjun Lee, Sarah Wassink, Hui He

J Mol Biol· July 2007

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An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.
Chingakham Ranjit Singh, Bumjun Lee, Tsuyoshi Udagawa, Sarah S Mohammad-Qureshi, Yasufumi Yamamoto

EMBO J· October 2006

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The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G.
Yasufumi Yamamoto, Chingakham Ranjit Singh, Assen Marintchev, Nathan S Hall, Ernest M Hannig

Proc Natl Acad Sci U S A· November 2005

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Eukaryotic translation initiation factor 5 is critical for integrity of the scanning preinitiation complex and accurate control of GCN4 translation.
Chingakham Ranjit Singh, Cynthia Curtis, Yasufumi Yamamoto, Nathan S Hall, Dustin S Kruse

Mol Cell Biol· July 2005

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