Publications by authors named "Chinyere Aloke"

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Dipeptidyl Peptidase 4 Inhibitors: Novel Therapeutic Agents in the Management of Type II Diabetes Mellitus.
Chinyere Aloke, Oluwasola Abayomi Adelusi, Olalekan Olugbenga Onisuru, Emmanuel Amarachi Iwuchukwu, Ikechukwu Achilonu

Pharmacoepidemiol Drug Saf· December 2025

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Ethanolic extract of leaves alleviates insulin resistance by modulating oxidative stress and inflammation in albino rats exposed to heavy metal mixture.
Uche Obasi Orji, Udu Ama Ibiam, Joshua Nonso Awoke, Ayomide Victor Atoki, Ejike Daniel Eze, Chinyere Aloke

Nat Prod Res· March 2025

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seed oil shields against cyclophosphamide-induced hepatorenal toxicity by modulating redox imbalance and iNOS/IL-β1 signalling in rats.
Amaka Cecilia Agbara, Ejike Daniel Eze, Christian Emeka Offor, Adam Moyosore Afodun, Ezebuilo Ugbala Ekpono, Chinyere Aloke

Heliyon· January 2025

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Glutathione S-transferase: A versatile and dynamic enzyme.
Chinyere Aloke, Olalekan Olugbenga Onisuru, Ikechukwu Achilonu

Biochem Biophys Res Commun· November 2024

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Exploring NAD metabolism and NNAT: Insights from structure, function, and computational modeling.
Olamide Jeje, Sarah Otun, Chinyere Aloke, Ikechukwu Achilonu

Biochimie· May 2024

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Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine.
Chinedu O Egwu, Chinyere Aloke, Kenneth T Onwe, Chukwunalu Igbudu Umoke, Joseph Nwafor

Molecules· May 2024

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Exploiting Copaifera salikounda compounds as treatment against diabetes: An insight into their potential targets from a computational perspective.
Chinyere Aloke, Emmanuel Amarachi Iwuchukwu, Ikechukwu Achilonu

Comput Biol Chem· June 2023

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Coping with the ESKAPE pathogens: Evolving strategies, challenges and future prospects.
Chinyere Aloke, Ikechukwu Achilonu

Microb Pathog· February 2023

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Assessment of the Antimalarial Treatment Failure in Ebonyi State, Southeast Nigeria.
Chinedu Ogbonnia Egwu, Chinyere Aloke, Jennifer Chukwu, Joshua Chidiebere Nwankwo, Chinemerem Irem

J Xenobiot· January 2023

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Combating Lassa Fever in West African Sub-Region: Progress, Challenges, and Future Perspectives.
Chinyere Aloke, Nwogo Ajuka Obasi, Patrick Maduabuchi Aja, Chinedum Uche Emelike, Chinedu Ogbonnia Egwu

Viruses· January 2023

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A world free of malaria: It is time for Africa to actively champion and take leadership of elimination and eradication strategies.
Chinedu Ogbonnia Egwu, Chinyere Aloke, Jennifer Chukwu, Anthony Agwu, Esther Alum

Afr Health Sci· December 2022

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Biophysical description of Bromosulfophthalein interaction with the 28-kDa glutathione transferase from Schistosoma japonicum.
Kagiso Pooe, Monare Thulo, Hattie Makumbe, Blessing Akumadu, Oluwatobin Otun, Chinyere Aloke

Mol Biochem Parasitol· November 2022

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Effects of co-treatment of Plasmodium berghei-infected mice with aqueous extract of Ocimum gratissimum leaves and primaquine on glucose-6-phosphate dehydrogenase activity, hematological, and antioxidant parameters.
Shedrach Kanu C, Chinyere Aloke, Nwabueze Elom I, Chinedum Eleazu O

J Ayurveda Integr Med· November 2022

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Phytochemicals from medicinal plants from African forests with potentials in rheumatoid arthritis management.
Chinyere Aloke, Ikenna C Ohanenye, Patrick M Aja, Chukwunonso E C C Ejike

J Pharm Pharmacol· September 2022

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Current Advances in the Management of Diabetes Mellitus.
Chinyere Aloke, Chinedu Ogbonnia Egwu, Patrick Maduabuchi Aja, Nwogo Ajuka Obasi, Jennifer Chukwu

Biomedicines· September 2022

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Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase.
Tasvi Daya, Olamide Jeje, Reabetswe Maake, Chinyere Aloke, Thandeka Khoza

Protein J· February 2022

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Impact of Drug Pressure versus Limited Access to Drug in Malaria Control: The Dilemma.
Chinedu Ogbonnia Egwu, Nwogo Ajuka Obasi, Chinyere Aloke, Joseph Nwafor, Ioannis Tsamesidis

Medicines (Basel)· January 2022

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Engineering a Pseudo-26-kDa Glutathione Transferase from / for Structure, Kinetics, and Ligandin Studies.
Neo Padi, Blessing Oluebube Akumadu, Olga Faerch, Chinyere Aloke, Vanessa Meyer

Biomolecules· December 2021

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Protective effects of Dialium guineense pulp on aspirin-induced gastric mucosal injury in albino rats.
Nwogo Ajuka Obasi, Chinyere Aloke, Stella Eberechukwu Obasi, Chinedu Ogbonnia Egwu, Ademola Clement Famurewa

J Appl Biomed· September 2021

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Seed Extract Attenuates Dyslipidemia in Testosterone Propionate-induced Benign Prostatic Hyperplasia in Rats.
Patience N Ogbu, Lawrence U S Ezeanyika, Victor N Eji Ogugua, Ikechukwu M Ogbu, Chinyere Aloke

Pak J Biol Sci· January 2021

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Studies on Ethanol Extracts of Against Carbon Tetrachloride-Induced Hepatotoxicity in Rats.
Chukwuemeka Ogbonna Okoro, Chinyere Aloke, Udu Ama Ibiam, Nwogo Ajuka Obasi, Obasi Uche Orji

Pak J Biol Sci· January 2021

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Antihyperglycemic, antihyperlipidemic and hepatoprotective effects of (Miq.) Miq. supplementation in alloxan-induced diabetic rats.
Chinyere Aloke, Ngwu Nwachukwu, Nwogo Ajuka Obasi, Chinedum Uche Emelike, Pascal Anyaegbunam Amu

Avicenna J Phytomed· January 2021

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Effect of acetogenin fraction of leaves on antioxidant status and some indices of benign prostatic hyperplasia in rats.
Patience N Ogbu, Evelyn O Ugota, Rita U Onwuka, Ikechukwu M Ogbu, Chinyere Aloke

Redox Rep· December 2020

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Elemental Composition and Associated Health Risk of Honey Obtained from Apiary Farms in Southeast Nigeria.
Nwogo Ajuka Obasi, Chinyere Aloke, Stella Eberechukwu Obasi, Ademola Clement Famurewa, Patience Nkemjika Ogbu

J Food Prot· October 2020

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Hesperidin protects against cadmium-induced pancreatitis by modulating insulin secretion, redox imbalance and iNOS/NF-ĸB signaling in rats.
Patrick M Aja, Friday I Izekwe, Ademola C Famurewa, Ezebuilo U Ekpono, Felix E Nwite, Chinyere Aloke

Life Sci· October 2020

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