Publications by authors named "Cho Tang"

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Novel potent orally active multitargeted receptor tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of 2-indolinone derivatives.
Tang Peng Cho, Su Yi Dong, Feng Jun, Fu Jian Hong, Yang Jiang Liang

J Med Chem· November 2010

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Synthesis and biological evaluation of azobicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes.
Tang Peng Cho, Yang Fang Long, Lin Zhi Gang, Wang Yang, Lu He Jun

Bioorg Med Chem Lett· June 2010

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Synthesis and biological evaluation of bicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes.
Tang Peng Cho, Lin Zhi Gang, Yang Fang Long, Wang Yang, Wang Qian

Bioorg Med Chem Lett· June 2010

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Synthetic small molecule furin inhibitors derived from 2,5-dideoxystreptamine.
Guan-Sheng Jiao, Lynne Cregar, Jinzhi Wang, Sherri Z Millis, Cho Tang

Proc Natl Acad Sci U S A· December 2006

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Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease.
Guan-Sheng Jiao, Ondrej Simo, Melissa Nagata, Sean O'Malley, Thomas Hemscheidt, Cho Tang

Bioorg Med Chem Lett· October 2006

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Guanidinylated 2,5-dideoxystreptamine derivatives as anthrax lethal factor inhibitors.
Guan-Sheng Jiao, Lynne Cregar, Mark E Goldman, Sherri Z Millis, Cho Tang

Bioorg Med Chem Lett· March 2006

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SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization.
Ismail Hassan Ismail, Susanne Mårtensson, Deborah Moshinsky, Audie Rice, Cho Tang

Oncogene· January 2004

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Design and synthesis of aminopropyl tetrahydroindole-based indolin-2-ones as selective and potent inhibitors of Src and Yes tyrosine kinase.
Huiping Guan, A Douglas Laird, Robert A Blake, Cho Tang, Chris Liang

Bioorg Med Chem Lett· January 2004

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A selective and oral small molecule inhibitor of vascular epithelial growth factor receptor (VEGFR)-2 and VEGFR-1 inhibits neovascularization and vascular permeability.
Neela Patel, Li Sun, Deborah Moshinsky, Hui Chen, Kathleen M Leahy, Cho Tang

J Pharmacol Exp Ther· September 2003

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Novel pyrrolyllactone and pyrrolyllactam indolinones as potent cyclin-dependent kinase 2 inhibitors.
Xiaoyuan Li, Ping Huang, Jingrong Jean Cui, Jennifer Zhang, Cho Tang

Bioorg Med Chem Lett· June 2003

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Structure-based design and discovery of novel inhibitors of protein tyrosine phosphatases.
Ping Huang, John Ramphal, James Wei, Congxin Liang, Bahija Jallal, Cho Tang

Bioorg Med Chem· April 2003

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Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase.
Li Sun, Chris Liang, Sheri Shirazian, Yong Zhou, Todd Miller, Flora Tang, Cho Tang

J Med Chem· March 2003

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In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.
Dirk B Mendel, A Douglas Laird, Xiaohua Xin, Sharianne G Louie, James G Christensen, Cho Tang

Clin Cancer Res· January 2003

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Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185(erbB)) tyrosine kinases.
Li Sun, Jean Cui, Congxin Liang, Yong Zhou, Asaad Nematalla, Cho Tang

Bioorg Med Chem Lett· August 2002

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