Publications by authors named "Choon Han Heh"

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Multifaceted anticancer mechanisms of tribenzyltin carboxylates: DNA minor groove targeting and inhibition of key enzymes in DNA replication, nucleotide synthesis, and redox homeostasis.
Theebaa Anasamy, Yiing Yee Foo, Wen Shang Saw, Yee Chu Kwa, Chuancheng Wei, Choon Han Heh

Naunyn Schmiedebergs Arch Pharmacol· December 2025

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Selective Stabilization of LRRK2 Kinase Conformations Reveals Distinct Modes of Action for Type I and II Inhibitors.
Chuancheng Wei, Choon Han Heh, Sek Peng Chin

Cell Biochem Biophys· September 2025

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Comparative Molecular Dynamics Reveals How LRRK2 Inhibitors Distinguish G2019S from Wild-Type.
Chuancheng Wei, Choon Han Heh, Lei Cheng Lit, Sek Peng Chin

Neurochem Res· August 2025

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Exploring the Impact of LRRK2 WD40 G2294R Mutation on Conformation and Dimerisation Dynamics: Insights From Molecular Dynamics Simulation.
Chuancheng Wei, Choon Han Heh, Sek Peng Chin

J Cell Biochem· February 2025

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An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms.
Yi Wei Chan, Choo Hock Tan, Choon Han Heh, Kae Yi Tan

Front Pharmacol· April 2023

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A Reverse Structure-based Design of HPV E7 Inhibitor.
Wan Chein Tan, Shatrah Othman, See Khai Lim, Nurshamimi Nor Rashid, Choon Han Heh

Curr Comput Aided Drug Des· November 2022

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Automated EGFR Peptide Inhibitor Elongation using Self-evolving Peptide Algorithm.
Ke Han Tan, Sek Peng Chin, Choon Han Heh

Curr Comput Aided Drug Des· July 2022

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Hit-to-Lead Short Peptides against Dengue Type 2 Envelope Protein: Computational and Experimental Investigations.
Norburhanuddin Johari Zaidi, Adib Afandi Abdullah, Choon Han Heh, Chun-Hung Lin, Rozana Othman

Molecules· May 2022

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Development of flexible electrochemical impedance spectroscopy-based biosensing platform for rapid screening of SARS-CoV-2 inhibitors.
Lik-Voon Kiew, Chia-Yu Chang, Sheng-Yu Huang, Pei-Wen Wang, Choon-Han Heh

Biosens Bioelectron· July 2021

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Rational drug discovery: Ellagic acid as a potent dual-target inhibitor against hepatitis C virus genotype 3 (HCV G3) NS3 enzymes.
See Khai Lim, Rozana Othman, Rohana Yusof, Choon Han Heh

Chem Biol Drug Des· January 2021

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Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives.
Hui Shi, Ren Ishikawa, Choon Han Heh, Shigeki Sasaki, Yosuke Taniguchi

Int J Mol Sci· January 2021

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Discovery of Dengue Virus Inhibitors.
Adib Afandi Abdullah, Yean Kee Lee, Sek Peng Chin, See Khai Lim, Vannajan Sanghiran Lee, Choon Han Heh

Curr Med Chem· September 2020

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Synthesis of γ-N-modified 8-oxo-2'-deoxyguanosine triphosphate and its characterization.
Ninticha Thavoncharoensub, Kento Maruyama, Choon Han Heh, Kok Hoong Leong, Hui Shi

Nucleosides Nucleotides Nucleic Acids· June 2019

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Sofosbuvir as treatment against dengue?
Chye Sheng Gan, See Khai Lim, Chin Fei Chee, Rohana Yusof, Choon Han Heh

Chem Biol Drug Des· February 2018

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Phosphodiesterase-5 inhibitors and their analogues as adulterants of herbal and food products: analysis of the Malaysian market, 2014-16.
Nur Baizura Bujang, Chin Fei Chee, Choon Han Heh, Noorsaadah Abd Rahman, Michael J C Buckle

Food Addit Contam Part A Chem Anal Control Expo Risk Assess· July 2017

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Variable clinical phenotypes in a family with homozygous c.1159G>A mutation in the thyroid peroxidase gene.
Ching Chin Lee, Fatimah Harun, Muhammad Yazid Jalaludin, Choon Han Heh, Rozana Othman

Horm Res Paediatr· February 2015

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Prevalence of c.2268dup and detection of two novel alterations, c.670_672del and c.1186C>T, in the TPO gene in a cohort of Malaysian-Chinese with thyroid dyshormonogenesis.
Ching Chin Lee, Fatimah Harun, Muhammad Yazid Jalaludin, Choon Han Heh, Rozana Othman

BMJ Open· January 2015

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A Novel, Homozygous c.1502T>G (p.Val501Gly) Mutation in the Thyroid peroxidase Gene in Malaysian Sisters with Congenital Hypothyroidism and Multinodular Goiter.
Ching Chin Lee, Fatimah Harun, Muhammad Yazid Jalaludin, Choon Han Heh, Rozana Othman

Int J Endocrinol· June 2013

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Boesenbergia rotunda: From Ethnomedicine to Drug Discovery.
Tan Eng-Chong, Lee Yean-Kee, Chee Chin-Fei, Heh Choon-Han, Wong Sher-Ming

Evid Based Complement Alternat Med· December 2012

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