Publications by authors named "Chris D Vulpe"

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Toxicophore-informed machine learning integrating Tox21 assay readouts for organ system-specific carcinogenicity prediction.
Chi-Yun Chen, Wei-Chun Chou, Venkata Nithin Kamineni, Pei-Yu Wu, Zhicheng Zhang, Chris D Vulpe

Environ Pollut· December 2025

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Genome-wide CRISPR Screen Reveal Targets of Chiral Gold(I) Anticancer Compound in Mammalian Cells.
Jong Hyun Kim, Samuel Ofori, Abderrahmane Tagmount, Chris D Vulpe, Samuel G Awuah

ACS Omega· November 2022

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Identifying Toxicity Mechanisms Associated with Early Lanthanide Exposure through Multidimensional Genome-Wide Screening.
Roger M Pallares, Dahlia D An, Solène Hébert, Alex Loguinov, Michael Proctor, Chris D Vulpe

ACS Omega· September 2022

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Genome-scale CRISPR screens identify host factors that promote human coronavirus infection.
Marco Grodzki, Andrew P Bluhm, Moritz Schaefer, Abderrahmane Tagmount, Max Russo, Chris D Vulpe

Genome Med· January 2022

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Organochlorine Pesticide Dieldrin Suppresses Cellular Interferon-Related Antiviral Gene Expression.
Max Russo, Sara T Humes, Ariana M Figueroa, Abderrahmane Tagmount, Ping Zhang, Chris D Vulpe

Toxicol Sci· August 2021

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Applying genome-wide CRISPR to identify known and novel genes and pathways that modulate formaldehyde toxicity.
Yun Zhao, Linqing Wei, Abderrahmane Tagmount, Alex Loguinov, Amin Sobh, Chris D Vulpe

Chemosphere· April 2021

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Functional Pathway Identification With CRISPR/Cas9 Genome-wide Gene Disruption in Human Dopaminergic Neuronal Cells Following Chronic Treatment With Dieldrin.
Max Russo, Amin Sobh, Ping Zhang, Alex Loguinov, Abderrahmane Tagmount, Chris D Vulpe

Toxicol Sci· August 2020

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Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition.
Louise B Thingholm, Malte C Rühlemann, Manja Koch, Brie Fuqua, Guido Laucke, Chris D Vulpe

Cell Host Microbe· August 2019

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Functional Profiling Identifies Determinants of Arsenic Trioxide Cellular Toxicity.
Amin Sobh, Alex Loguinov, Gulce Naz Yazici, Rola S Zeidan, Abderrahmane Tagmount, Chris D Vulpe

Toxicol Sci· May 2019

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Genome-Wide CRISPR Screening Identifies the Tumor Suppressor Candidate OVCA2 As a Determinant of Tolerance to Acetaldehyde.
Amin Sobh, Alex Loguinov, Alessia Stornetta, Silvia Balbo, Abderrahmane Tagmount, Chris D Vulpe

Toxicol Sci· May 2019

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Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin.
Brie K Fuqua, Yan Lu, David M Frazer, Deepak Darshan, Sarah J Wilkins, Chris D Vulpe

Cell Mol Gastroenterol Hepatol· April 2019

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A comparison between whole transcript and 3' RNA sequencing methods using Kapa and Lexogen library preparation methods.
Feiyang Ma, Brie K Fuqua, Yehudit Hasin, Clara Yukhtman, Chris D Vulpe

BMC Genomics· January 2019

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Transcriptomic and Network Analyses Reveal Mechanistic-Based Biomarkers of Endocrine Disruption in the Marine Mussel, Mytilus edulis.
Bonnie J Blalock, William E Robinson, Alexandre Loguinov, Chris D Vulpe, Keegan S Krick

Environ Sci Technol· August 2018

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Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux.
Min Chen, Jiashuo Zheng, Guohao Liu, En Xu, Junzhuo Wang, Chris D Vulpe

Redox Biol· July 2018

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The Toxicogenome of Hyalella azteca: A Model for Sediment Ecotoxicology and Evolutionary Toxicology.
Helen C Poynton, Simone Hasenbein, Joshua B Benoit, Maria S Sepulveda, Monica F Poelchau, Chris D Vulpe

Environ Sci Technol· May 2018

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Multi-Copper Ferroxidase-Deficient Mice Have Increased Brain Iron Concentrations and Learning and Memory Deficits.
Jiashuo Zheng, Ruiwei Jiang, Min Chen, Zaitunamu Maimaitiming, Junzhuo Wang, Chris D Vulpe

J Nutr· April 2018

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mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice.
Stela McLachlan, Kathryn E Page, Seung-Min Lee, Alex Loguinov, Erika Valore, Chris D Vulpe

Am J Physiol Gastrointest Liver Physiol· November 2017

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Editor's Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes.
Vanessa Y De La Rosa, Jonathan Asfaha, Michael Fasullo, Alex Loguinov, Peng Li, Chris D Vulpe

Toxicol Sci· November 2017

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Intestinal hephaestin potentiates iron absorption in weanling, adult, and pregnant mice under physiological conditions.
Caglar Doguer, Jung-Heun Ha, Sukru Gulec, Chris D Vulpe, Gregory J Anderson

Blood Adv· July 2017

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Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney.
Bo Jiang, Guohao Liu, Jiashuo Zheng, Mengxia Chen, Zaitunamu Maimaitiming, Chris D Vulpe

Sci Rep· December 2016

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Functional Toxicogenomic Profiling Expands Insight into Modulators of Formaldehyde Toxicity in Yeast.
Matthew North, Brandon D Gaytán, Carlos Romero, Vanessa Y De La Rosa, Alex Loguinov, Chris D Vulpe

Front Genet· November 2016

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Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells.
Shawn Pan, Chaoshen Yuan, Abderrahmane Tagmount, Ruthann A Rudel, Janet M Ackerman, Chris D Vulpe

Environ Health Perspect· May 2016

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Ecotoxicogenomics: Microarray interlaboratory comparability.
Doris E Vidal-Dorsch, Steven M Bay, Shelly Moore, Blythe Layton, Alvine C Mehinto, Chris D Vulpe

Chemosphere· February 2016

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Gene transcription, metabolite and lipid profiling in eco-indicator daphnia magna indicate diverse mechanisms of toxicity by legacy and emerging flame-retardants.
Leona D Scanlan, Alexandre V Loguinov, Quincy Teng, Philipp Antczak, Kathleen P Dailey, Chris D Vulpe

Environ Sci Technol· June 2015

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Hephaestin and ceruloplasmin play distinct but interrelated roles in iron homeostasis in mouse brain.
Ruiwei Jiang, Chao Hua, Yike Wan, Bo Jiang, Huiyin Hu, Chris D Vulpe

J Nutr· May 2015

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