Publications by authors named "Chrishan J Ramachandra"

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Patient-derived induced pluripotent stem cell models reveal mechanistic links between aberrant mitochondrial dynamics and cardiomyopathy.
Chrishan J Ramachandra

Pediatr Res· November 2025

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Interleukin 11 therapy causes acute left ventricular dysfunction.
Mark Sweeney, Katie O'Fee, Chelsie Villanueva-Hayes, Ekhlas Rahman, Michael Lee, Chrishan J Ramachandra

Cardiovasc Res· December 2024

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Distinguishing heart failure with reduced ejection fraction from heart failure with preserved ejection fraction: A phenomics approach.
Bart J van Essen, Ganash N Tharshana, Wouter Ouwerkerk, Poh Suan Daniel Yeo, David Sim, Chrishan J Ramachandra

Eur J Heart Fail· April 2024

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Metabolic reprogramming of immune cells by mitochondrial division inhibitor-1 to prevent post-vascular injury neointimal hyperplasia.
Gustavo E Crespo-Avilan, Sauri Hernandez-Resendiz, Chrishan J Ramachandra, Victor Ungureanu, Ying-Hsi Lin

Atherosclerosis· March 2024

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Unravelling the Interplay between Cardiac Metabolism and Heart Regeneration.
Fan Yu, Shuo Cong, En Ping Yap, Derek J Hausenloy, Chrishan J Ramachandra

Int J Mol Sci· June 2023

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Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury through a sirtuin-3 mediated increase in fatty acid oxidation.
Andrew R Hall, Qutuba G Karwi, Sanjeev Kumar, Rachel Dongworth, Dunja Aksentijević, Chrishan J Ramachandra

Sci Rep· November 2022

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Protecting the Mitochondria in Cardiac Disease.
Antigone Lazou, Chrishan J Ramachandra

Int J Mol Sci· July 2022

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Targeting the Metabolic-Inflammatory Circuit in Heart Failure With Preserved Ejection Fraction.
En Ping Yap, Myu Mai Ja Kp, Chrishan J Ramachandra

Curr Heart Fail Rep· June 2022

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The KCNH2-IVS9-28A/G mutation causes aberrant isoform expression and hERG trafficking defect in cardiomyocytes derived from patients affected by Long QT Syndrome type 2.
Manuela Mura, Ashish Mehta, Chrishan J Ramachandra, Rita Zappatore, Federica Pisano

Int J Cardiol· August 2017

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ErbB Receptor Tyrosine Kinase: A Molecular Switch Between Cardiac and Neuroectoderm Specification in Human Pluripotent Stem Cells.
Chrishan J A Ramachandra, Ashish Mehta, Chong Hui Lua, Anuja Chitre, K P Myu Mai Ja

Stem Cells· October 2016

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Molecular pathogenesis of Marfan syndrome.
Chrishan J A Ramachandra, Ashish Mehta, Kenneth Wei Qiang Guo, Philip Wong, Ju Le Tan

Int J Cardiol· May 2016

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ErbB4 Activated p38γ MAPK Isoform Mediates Early Cardiogenesis Through NKx2.5 in Human Pluripotent Stem Cells.
Chrishan J A Ramachandra, Ashish Mehta, Philip Wong, Winston Shim

Stem Cells· February 2016

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A systemic evaluation of cardiac differentiation from mRNA reprogrammed human induced pluripotent stem cells.
Ashish Mehta, Vinod Verma, Manasi Nandihalli, Chrishan J A Ramachandra, Glen L Sequiera

PLoS One· December 2015

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Evaluation of sarcomeric organization in human pluripotent stem cell-derived cardiomyocytes.
Chrishan J A Ramachandra, Winston Shim

Methods Mol Biol· December 2015

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Phasic modulation of Wnt signaling enhances cardiac differentiation in human pluripotent stem cells by recapitulating developmental ontogeny.
Ashish Mehta, Chrishan J A Ramachandra, Glen L Sequiera, Yuliansa Sudibyo, Manasi Nandihalli

Biochim Biophys Acta· November 2014

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Re-trafficking of hERG reverses long QT syndrome 2 phenotype in human iPS-derived cardiomyocytes.
Ashish Mehta, Glen Lester Sequiera, Chrishan J A Ramachandra, Yuliansa Sudibyo, Yingying Chung

Cardiovasc Res· June 2014

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Targeted transgene insertion into the AAVS1 locus driven by baculoviral vector-mediated zinc finger nuclease expression in human-induced pluripotent stem cells.
Felix Chang Tay, Wee Kiat Tan, Sal-Lee Goh, Chrishan J A Ramachandra, Cia-Hin Lau

J Gene Med· October 2013

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Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors.
Chrishan J A Ramachandra, Mohammad Shahbazi, Timothy W X Kwang, Yukti Choudhury, Xiao Ying Bak

Nucleic Acids Res· September 2011

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