Publications by authors named "Chrislean Jun Botanas"

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4-F-PCP, a Novel PCP Analog Ameliorates the Depressive-Like Behavior of Chronic Social Defeat Stress Mice via NMDA Receptor Antagonism.
Darlene Mae D Ortiz, Mikyung Kim, Hyun Jun Lee, Chrislean Jun Botanas, Raly James Perez Custodio

Biomol Ther (Seoul)· March 2023

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Corrigendum to 'R (-) methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamine' [Neuropharmacology 193 (2021) 108619].
Chrislean Jun Botanas, Raly James Perez Custodio, Hee Jin Kim, June Bryan de la Pena, Leandro Val Sayson

Neuropharmacology· November 2021

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R (-)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamine.
Chrislean Jun Botanas, Raly James Perez Custodio, Hee Jin Kim, June Bryan de la Pena, Leandro Val Sayson

Neuropharmacology· August 2021

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The dopaminergic alterations induced by 4-F-PCP and 4-Keto-PCP may enhance their drug-induced rewarding and reinforcing effects: Implications for abuse.
Darlene Mae Ortiz, Raly James Perez Custodio, Arvie Abiero, Chrislean Jun Botanas, Leandro Val Sayson

Addict Biol· July 2021

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1-Phenylcyclohexan-1-amine hydrochloride (PCA HCl) alters mesolimbic dopamine system accompanied by neuroplastic changes: A neuropsychopharmacological evaluation in rodents.
Arvie Abiero, Raly James Perez Custodio, Chrislean Jun Botanas, Darlene Mae Ortiz, Leandro Val Sayson

Neurochem Int· March 2021

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25B-NBOMe, a novel N-2-methoxybenzyl-phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: Evidence of abuse potential.
Raly James Perez Custodio, Leandro Val Sayson, Chrislean Jun Botanas, Arvie Abiero, Kyung Yi You

Addict Biol· November 2020

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Two newly-emerging substituted phenethylamines MAL and BOD induce differential psychopharmacological effects in rodents.
Raly James Perez Custodio, Leandro Val Sayson, Chrislean Jun Botanas, Arvie Abiero, Mikyung Kim

J Psychopharmacol· September 2020

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Catalpol and Mannitol, Two Components of , Exhibit Anticonvulsant Effects Probably via GABA Receptor Regulation.
Mikyung Kim, Srijan Acharya, Chrislean Jun Botanas, Raly James Custodio, Hyun Jun Lee

Biomol Ther (Seoul)· March 2020

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4-MeO-PCP and 3-MeO-PCMo, new dissociative drugs, produce rewarding and reinforcing effects through activation of mesolimbic dopamine pathway and alteration of accumbal CREB, deltaFosB, and BDNF levels.
Arvie Abiero, Chrislean Jun Botanas, Raly James Custodio, Leandro Val Sayson, Mikyung Kim

Psychopharmacology (Berl)· March 2020

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Four Novel Synthetic Tryptamine Analogs Induce Head-Twitch Responses and Increase 5-HTR2a in the Prefrontal Cortex in Mice.
Arvie Abiero, In Soo Ryu, Chrislean Jun Botanas, Raly James Perez Custodio, Leandro Val Sayson

Biomol Ther (Seoul)· January 2020

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The circadian gene, Per2, influences methamphetamine sensitization and reward through the dopaminergic system in the striatum of mice.
Mikyung Kim, Raly James Custodio, Chrislean Jun Botanas, June Bryan de la Peña, Leandro Val Sayson

Addict Biol· September 2019

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The novel methoxetamine analogs N-ethylnorketamine hydrochloride (NENK), 2-MeO-N-ethylketamine hydrochloride (2-MeO-NEK), and 4-MeO-N-ethylketamine hydrochloride (4-MeO-NEK) elicit rapid antidepressant effects via activation of AMPA and 5-HT receptors.
Leandro Val Sayson, Chrislean Jun Botanas, Raly James Perez Custodio, Arvie Abiero, Mikyung Kim

Psychopharmacology (Berl)· July 2019

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5-Methoxy-α-methyltryptamine (5-MeO-AMT), a tryptamine derivative, induces head-twitch responses in mice through the activation of serotonin receptor 2a in the prefrontal cortex.
Arvie Abiero, Chrislean Jun Botanas, Leandro Val Sayson, Raly James Custodio, June Bryan de la Peña

Behav Brain Res· February 2019

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The Atxn7-overexpressing mice showed hyperactivity and impulsivity which were ameliorated by atomoxetine treatment: A possible animal model of the hyperactive-impulsive phenotype of ADHD.
Irene Joy I Dela Peña, Chrislean Jun Botanas, June Bryan de la Peña, Raly James Custodio, Ike Dela Peña

Prog Neuropsychopharmacol Biol Psychiatry· January 2019

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Methoxetamine: A foe or friend?
Chrislean Jun Botanas, June Bryan de la Peña, Hee Jin Kim, Yong Sup Lee, Jae Hoon Cheong

Neurochem Int· January 2019

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Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice.
Raly James Perez Custodio, Chrislean Jun Botanas, June Bryan de la Peña, Irene Joy Dela Peña, Mikyung Kim

Neuroscience· October 2018

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Exploring the Validity of Proposed Transgenic Animal Models of Attention-Deficit Hyperactivity Disorder (ADHD).
June Bryan de la Peña, Irene Joy Dela Peña, Raly James Custodio, Chrislean Jun Botanas, Hee Jin Kim

Mol Neurobiol· May 2018

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A new synthetic drug 5-(2-aminopropyl)indole (5-IT) induces rewarding effects and increases dopamine D1 receptor and dopamine transporter mRNA levels.
Chrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, Irene Joy Dela Peña, Mikyung Kim

Behav Brain Res· April 2018

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Methoxetamine produces rapid and sustained antidepressant effects probably via glutamatergic and serotonergic mechanisms.
Chrislean Jun Botanas, June Bryan de la Peña, Raly James Custodio, Irene Joy Dela Peña, Mikyung Kim

Neuropharmacology· November 2017

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Evaluation of the Abuse Potential of Novel Amphetamine Derivatives with Modifications on the Amine (NBNA) and Phenyl (EDA, PMEA, 2-APN) Sites.
Raly James Perez Custodio, Chrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, Irene Joy Dela Peña

Biomol Ther (Seoul)· November 2017

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The psychopharmacological activities of Vietnamese ginseng in mice: characterization of its psychomotor, sedative-hypnotic, antistress, anxiolytic, and cognitive effects.
Irene Joy I Dela Peña, Hee Jin Kim, Chrislean Jun Botanas, June Bryan de la Peña, Thi Hong Van Le

J Ginseng Res· April 2017

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The Abuse Potential of α-Piperidinopropiophenone (PIPP) and α-Piperidinopentiothiophenone (PIVT), Two New Synthetic Cathinones with Piperidine Ring Substituent.
Chrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, Irene Joy Dela Peña, Mikyung Kim

Biomol Ther (Seoul)· March 2017

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The abuse potential of two novel synthetic cathinones with modification on the alpha-carbon position, 2-cyclohexyl-2-(methylamino)-1-phenylethanone (MACHP) and 2-(methylamino)-1-phenyloctan-1-one (MAOP), and their effects on dopaminergic activity.
Chrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, Irene Joy Dela Peña, Mikyung Kim

Pharmacol Biochem Behav· February 2017

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A novel synthetic cathinone, 2-(methylamino)-1-(naphthalen-2-yl) propan-1-one (BMAPN), produced rewarding effects and altered striatal dopamine-related gene expression in mice.
Chrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, Irene Joy Dela Peña, Mikyung Kim

Behav Brain Res· January 2017

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Cigarette smoke exposure during adolescence but not adulthood induces anxiety-like behavior and locomotor stimulation in rats during withdrawal.
June Bryan de la Peña, Hafiz Muhammad Ahsan, Chrislean Jun Botanas, Irene Joy Dela Peña, Taeseon Woo

Int J Dev Neurosci· December 2016

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