Publications by authors named "Christian Cave"

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Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy.
Lhana Tisseur, Cédric Logé, Sandrine Cojean, Khadidiatou Gassama, Lilian Karcher

RSC Med Chem· June 2025

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Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition.
Lhana Tisseur, Sandrine Cojean, Khadidiatou Gassama, Cédric Logé, Fabrice Pagniez

ChemMedChem· March 2025

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Enhancing public health response: a framework for topics and sentiment analysis of COVID-19 in the UK using Twitter and the embedded topic model.
Aisha Aldosery, Robert Carruthers, Karandeep Kay, Christian Cave, Paul Reynolds

Front Public Health· March 2024

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Molecular mechanisms in Alzheimer's disease and related potential treatments such as structural target convergence of antibodies and simple organic molecules.
Nassima Oumata, Kui Lu, Yuou Teng, Christian Cavé, Yu Peng

Eur J Med Chem· October 2022

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In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition.
Marc-Antoine Bazin, Sandrine Cojean, Fabrice Pagniez, Guillaume Bernadat, Christian Cavé

Eur J Med Chem· January 2021

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GDP-Mannose Pyrophosphorylase: A Biologically Validated Target for Drug Development Against Leishmaniasis.
Sébastien Pomel, Wei Mao, Tâp Ha-Duong, Christian Cavé, Philippe M Loiseau

Front Cell Infect Microbiol· February 2020

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Synthesis and Antimalarial Activity of 1,4-Disubstituted Piperidine Derivatives.
Rokhyatou Seck, Abdoulaye Gassama, Sandrine Cojean, Christian Cavé

Molecules· January 2020

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In Silico Target Druggability Assessment: From Structural to Systemic Approaches.
Jean-Yves Trosset, Christian Cavé

Methods Mol Biol· July 2019

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In Silico Drug-Target Profiling.
Jean-Yves Trosset, Christian Cavé

Methods Mol Biol· July 2019

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Biochemical analysis of leishmanial and human GDP-Mannose Pyrophosphorylases and selection of inhibitors as new leads.
Wei Mao, Pierre Daligaux, Noureddine Lazar, Tâp Ha-Duong, Christian Cavé

Sci Rep· April 2017

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Simple and efficient synthesis of 5'-aryl-5'-deoxyguanosine analogs by azide-alkyne click reaction and their antileishmanial activities.
Pierre Daligaux, Sébastien Pomel, Karine Leblanc, Philippe M Loiseau, Christian Cavé

Mol Divers· May 2016

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Comparative study of structural models of Leishmania donovani and human GDP-mannose pyrophosphorylases.
Pierre Daligaux, Guillaume Bernadat, Linh Tran, Christian Cavé, Philippe M Loiseau

Eur J Med Chem· January 2016

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Asymmetric reduction of β-ketoesters and chiral β-iminoesters: impact of a α-quaternary stereocenter.
Hadia Almahli, Frédéric Hendra, Claire Troufflard, Christian Cavé, Delphine Joseph

Chirality· March 2011

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Auditory-tactile speech perception in congenitally blind and sighted adults.
Marc Sato, Christian Cavé, Lucie Ménard, Annie Brasseur

Neuropsychologia· October 2010

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Are eyebrow movements linked to voice variations and turn-taking in dialogue? An experimental investigation.
Isabelle Guaïtella, Serge Santi, Benoît Lagrue, Christian Cavé

Lang Speech· February 2010

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Regio- and diastereocontrolled preparative oxidation of methyloctalones by a biomimetic porphyrin catalyst.
Bernardin Akagah, François Estour, Philippe Vérité, Pédro Lameiras, Mohammed Nour

Chirality· July 2004

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Asymmetric Michael reaction involving chiral imines/secondary enamines: stereocontrolled synthesis of 2,2-disubstituted tetrahydrothiophen-3-ones.
Didier Desmaële, Sandrine Delarue-Cochin, Christian Cavé, Jean D'Angelo, Georges Morgant

Org Lett· July 2004

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Stereochemical Aspects in the Asymmetric Michael Addition of Chiral Imines to Substituted Electrophilic Alkenes.
Christian Cavé, Didier Desmaële, Jean d'Angelo, Claude Riche, Angèle Chiaroni

J Org Chem· June 1996

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