Publications by authors named "Christian Frisch"

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Recombinant Anti-idiotypic Antibodies in Ligand Binding Assays for Antibody Drug Development.
Stefan Harth, Christian Frisch

Methods Mol Biol· March 2021

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Generation by phage display and characterization of drug-target complex-specific antibodies for pharmacokinetic analysis of biotherapeutics.
Stefan Harth, Andre Ten Haaf, Christian Loew, Christian Frisch, Achim Knappik

MAbs· January 2019

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Intrauterine valproate exposure is associated with alterations in hippocampal cell numbers and folate metabolism in a rat model of valproate teratogenicity.
Alexander Semmler, Christian Frisch, Christiane Bleul, Desiree Smith, Laurent Bigler

Seizure· March 2017

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Crystallization and preliminary X-ray crystallographic analysis of the sclerostin-neutralizing Fab AbD09097.
Verena Boschert, Eva Maria Muth, Achim Knappik, Christian Frisch, Thomas D Mueller

Acta Crystallogr F Struct Biol Commun· April 2015

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Object location performance: detection of functional impairment in right temporal lobe epilepsy.
Christian Frisch, Christoph Helmstaedter

Epilepsy Behav· June 2014

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High-affinity recombinant antibody fragments (Fabs) can be applied in peptide enrichment immuno-MRM assays.
Jeffrey R Whiteaker, Lei Zhao, Christian Frisch, Francisco Ylera, Stefan Harth

J Proteome Res· April 2014

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Anti-Sclerostin antibody inhibits internalization of Sclerostin and Sclerostin-mediated antagonism of Wnt/LRP6 signaling.
Maarten van Dinther, Juan Zhang, Stella E Weidauer, Verena Boschert, Eva-Maria Muth, Christian Frisch

PLoS One· November 2013

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Off-rate screening for selection of high-affinity anti-drug antibodies.
Francisco Ylera, Stefan Harth, Dirk Waldherr, Christian Frisch, Achim Knappik

Anal Biochem· October 2013

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An efficient method for fractionated whole rodent brain radiation.
Alexander Semmler, Stephan Garbe, Susanna Moskau, Christian Frisch, Nicole Eter

Neurol Res· May 2013

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The ratio of S-adenosylmethione and S-adenosyl-homocysteine is increased in the brains of newborn rats in a model of valproic acid teratogenicity.
Alexander Semmler, Christian Frisch, Desiree Smith, Henk Blom, Michael Linnebank

Toxicology· March 2012

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Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41.
Elena Gustchina, Mi Li, John M Louis, D Eric Anderson, John Lloyd, Christian Frisch

PLoS Pathog· November 2010

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Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B-NS3 proteinase of West Nile virus.
Sergey A Shiryaev, Ilian A Radichev, Boris I Ratnikov, Alexander E Aleshin, Katarzyna Gawlik, Christian Frisch

Biochem J· April 2010

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Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth.
Elena Gustchina, John M Louis, Christian Frisch, Francisco Ylera, Annette Lechner

Virology· October 2009

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Positive correlation between the density of neuropeptide y positive neurons in the amygdala and parameters of self-reported anxiety and depression in mesiotemporal lobe epilepsy patients.
Christian Frisch, Joachim Hanke, Sven Kleinerüschkamp, Sandra Röske, Sabine Kaaden

Biol Psychiatry· September 2009

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Development of recombinant human IgA for anticardiolipin antibodies assay standardization.
Achim Knappik, Francesco Capuano, Christian Frisch, Francisco Ylera, Fabrizio Bonelli

Ann N Y Acad Sci· September 2009

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Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat.
Christian Frisch, Kerstin Hüsch, Frank Angenstein, Alexei Kudin, Wolfram Kunz

Epilepsia· June 2009

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The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.
Christine Rothe, Stefanie Urlinger, Corinna Löhning, Josef Prassler, Yvonne Stark, Christian Frisch

J Mol Biol· February 2008

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Selection of vimentin-specific antibodies from the HuCAL phage display library by subtractive panning on formalin-fixed, paraffin-embedded tissue.
Tiantom Jarutat, Cora Nickels, Christian Frisch, Florian Stellmacher, Kai Peter Hofig

Biol Chem· June 2007

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Intrathecal viral replication and cerebral deficits in different stages of human immunodeficiency virus disease.
Gabriele Arendt, Thorsten Nolting, Christian Frisch, Ingo-Wilhelm Husstedt, Nora Gregor

J Neurovirol· June 2007

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Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model.
Alexander Semmler, Christian Frisch, Thomas Debeir, Mutiah Ramanathan, Thorsten Okulla

Exp Neurol· April 2007

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Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent.
Christian Frisch, Alexei P Kudin, Christian E Elger, Wolfram S Kunz, Christoph Helmstaedter

Epilepsy Res· February 2007

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Isolation and comparative characterization of Ki-67 equivalent antibodies from the HuCAL phage display library.
Tiantom Jarutat, Christian Frisch, Cora Nickels, Hartmut Merz, Achim Knappik

Biol Chem· July 2006

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Antibodies for proteomic research: comparison of traditional immunization with recombinant antibody technology.
Reiko Ohara, Achim Knappik, Kiyo Shimada, Christian Frisch, Francisco Ylera

Proteomics· May 2006

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Volumetric magnetic resonance imaging of functionally relevant structural alterations in chronic epilepsy after pilocarpine-induced status epilepticus in rats.
Heiko G Niessen, Frank Angenstein, Stefan Vielhaber, Christian Frisch, Alexei Kudin

Epilepsia· July 2005

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Mice with astrocyte-directed inactivation of connexin43 exhibit increased exploratory behaviour, impaired motor capacities, and changes in brain acetylcholine levels.
Christian Frisch, Martin Theis, Maria A De Souza Silva, Ekrem Dere, Goran Söhl

Eur J Neurosci· October 2003

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