Publications by authors named "Christian Janzen"

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A Leishmania virulence factor harnesses an allosteric kinase switch to regulate its ubiquitin ligase activity.
Thornton J Fokkens, Elisa T Rauh, Madita Wolter, Heidi Sebald, Melina Mitnacht, Christian J Janzen

Mol Cell· October 2025

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The histone methyltransferase DOT1B is dispensable for stage differentiation and macrophage infection of .
Nicole Eisenhuth, Elisa Theres Rauh, Melina Mitnacht, Andrea Debus, Ulrike Schleicher, Christian J Janzen

Front Cell Infect Microbiol· May 2025

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TelAP2 links TelAP1 to the telomere complex in Trypanosoma brucei.
Nadine Weisert, Verena Majewski, Laura Hartleb, Katarina Luko, Liudmyla Lototska, Christian J Janzen

Sci Rep· December 2024

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Characterisation of TbSmee1 suggests endocytosis allows surface-bound cargo to enter the trypanosome flagellar pocket.
Daja Schichler, Antonia Konle, Eva-Maria Spath, Sina Riegler, Alexandra Klein, Christian J Janzen

J Cell Sci· October 2023

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Magnetic patterning of Co/Ni layered systems by plasma oxidation.
Błażej Anastaziak, Weronika Andrzejewska, Marek Schmidt, Michał Matczak, Ivan Soldatov, Christian Janzen

Sci Rep· December 2022

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A novel SNF2 ATPase complex in Trypanosoma brucei with a role in H2A.Z-mediated chromatin remodelling.
Tim Vellmer, Laura Hartleb, Albert Fradera Sola, Susanne Kramer, Elisabeth Meyer-Natus, Christian J Janzen

PLoS Pathog· June 2022

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A DOT1B/Ribonuclease H2 Protein Complex Is Involved in R-Loop Processing, Genomic Integrity, and Antigenic Variation in Trypanosoma brucei.
Nicole Eisenhuth, Tim Vellmer, Elisa T Rauh, Falk Butter, Christian J Janzen

mBio· December 2021

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Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation.
Andrea Zurita Leal, Marie Schwebs, Emma Briggs, Nadine Weisert, Helena Reis, Christian J Janzen

Nucleic Acids Res· September 2020

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Trimethylation of histone H3K76 by Dot1B enhances cell cycle progression after mitosis in Trypanosoma cruzi.
Vinicius Santana Nunes, Nilmar Silvio Moretti, Marcelo Santos da Silva, Maria Carolina Elias, Christian J Janzen

Biochim Biophys Acta Mol Cell Res· July 2020

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Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei.
Eva Doleželová, Michaela Kunzová, Mario Dejung, Michal Levin, Brian Panicucci, Christian J Janzen

PLoS Biol· June 2020

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Genome organization and DNA accessibility control antigenic variation in trypanosomes.
Laura S M Müller, Raúl O Cosentino, Konrad U Förstner, Julien Guizetti, Carolin Wedel, Christian J Janzen

Nature· November 2018

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TelAP1 links telomere complexes with developmental expression site silencing in African trypanosomes.
Helena Reis, Marie Schwebs, Sabrina Dietz, Christian J Janzen, Falk Butter

Nucleic Acids Res· April 2018

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The nuclear proteome of Trypanosoma brucei.
Carina Goos, Mario Dejung, Christian J Janzen, Falk Butter, Susanne Kramer

PLoS One· September 2017

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A quorum sensing-independent path to stumpy development in Trypanosoma brucei.
Henriette Zimmermann, Ines Subota, Christopher Batram, Susanne Kramer, Christian J Janzen

PLoS Pathog· April 2017

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Two flagellar BAR domain proteins in Trypanosoma brucei with stage-specific regulation.
Zdenka Cicova, Mario Dejung, Tomas Skalicky, Nicole Eisenhuth, Steffen Hanselmann, Christian J Janzen

Sci Rep· October 2016

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Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi.
Teresa Cristina Leandro de Jesus, Vinícius Santana Nunes, Mariana de Camargo Lopes, Daiana Evelin Martil, Leo Kei Iwai, Christian Janzen

J Proteome Res· June 2016

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Quantitative Proteomics Uncovers Novel Factors Involved in Developmental Differentiation of Trypanosoma brucei.
Mario Dejung, Ines Subota, Ferdinand Bucerius, Gülcin Dindar, Anja Freiwald, Christian J Janzen

PLoS Pathog· February 2016

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Fragment ion patchwork quantification for measuring site-specific acetylation degrees.
Rasha ElBashir, Jens T Vanselow, Amelie Kraus, Christian J Janzen, T Nicolai Siegel

Anal Chem· October 2015

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Structure-guided mutational analysis reveals the functional requirements for product specificity of DOT1 enzymes.
Gülcin Dindar, Andreas M Anger, Christine Mehlhorn, Sandra B Hake, Christian J Janzen

Nat Commun· November 2014

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Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei.
Christopher Batram, Nicola G Jones, Christian J Janzen, Sebastian M Markert, Markus Engstler

Elife· May 2014

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Characterization of two different Asf1 histone chaperones with distinct cellular localizations and functions in Trypanosoma brucei.
Bruno Pascoalino, Gülcin Dindar, João P Vieira-da-Rocha, Carlos Renato Machado, Christian J Janzen

Nucleic Acids Res· March 2014

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Comparative proteomics of two life cycle stages of stable isotope-labeled Trypanosoma brucei reveals novel components of the parasite's host adaptation machinery.
Falk Butter, Ferdinand Bucerius, Margaux Michel, Zdenka Cicova, Matthias Mann, Christian J Janzen

Mol Cell Proteomics· January 2013

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DOT1A-dependent H3K76 methylation is required for replication regulation in Trypanosoma brucei.
Alwine Gassen, Doris Brechtefeld, Niklas Schandry, J Manuel Arteaga-Salas, Lars Israel, Christian J Janzen

Nucleic Acids Res· November 2012

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Regulation and spatial organization of PCNA in Trypanosoma brucei.
Doris Kaufmann, Alwine Gassen, Andreas Maiser, Heinrich Leonhardt, Christian J Janzen

Biochem Biophys Res Commun· March 2012

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Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei.
Floor Frederiks, Tibor van Welsem, Gideon Oudgenoeg, Albert J R Heck, Christian J Janzen

J Cell Sci· December 2010

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