Publications by authors named "Christian Leguern"

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PD-L1 on ex-vivo Expanded Toll-like-receptor-Bregs Prevents Allograft Rejection by Breg Viability Promotion, CD4T Effector Cell Suppression, and Tregs Induction.
Minxue Liao, Jing Liu, Kang Mi Lee, Katsuhiro Tomofuji, Naoki Tanimine, Christian Leguern

Am J Transplant· September 2025

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The inhibitory receptor Siglec-E controls antigen-presenting cell activation and T cell-mediated transplant rejection.
Thiago J Borges, Karina Lima, Rodrigo B Gassen, Kaifeng Liu, Yoshikazu Ganchiku, Christian LeGuern

Sci Transl Med· May 2025

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A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models.
Orhan Efe, Rodrigo B Gassen, Leela Morena, Yoshikazu Ganchiku, Ayman Al Jurdi, Christian LeGuern

J Clin Invest· March 2024

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Regulatory CD4 T cells: permanent or temporary suppressors of immunity.
Christian LeGuern, James F Markmann

Front Immunol· February 2024

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Lack of IFN-γ Receptor Signaling Inhibits Graft-versus-Host Disease by Potentiating Regulatory T Cell Expansion and Conversion.
Naicui Zhai, Wentao Liu, Chun-Hui Jin, Yanan Ding, Liguang Sun, Christian LeGuern

J Immunol· September 2023

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Leveraging the tolerogenic potential of TNF-α and regulatory B cells in organ transplantation.
Sonya A Poznansky, Matthew Yu, Kevin Deng, Qiang Fu, James F Markmann, Christian LeGuern

Front Immunol· May 2023

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Suppression of allograft rejection by regulatory B cells induced via TLR signaling.
Kang Mi Lee, Qiang Fu, Guoli Huai, Kevin Deng, Ji Lei, Christian LeGuern

JCI Insight· September 2022

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The 2022 FASEB virtual Catalyst Conference on B Cells in Injury and Regeneration, March 30, 2022.
Liam J Dwyer, Ann M Stowe, Kristian Doyle, Phillip Popovich, Elizabeth Engler-Chiurazzi, Christian LeGuern

FASEB J· August 2022

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Interleukin-27 in liver xenotransplantation: A rational target to mitigate ischemia reperfusion injury and increase xenograft survival.
Rudy Matheson, Kevin Deng, Guoli Huai, Kang Mi Lee, Noel Feeney, Christian LeGuern

Transplant Rev (Orlando)· January 2022

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Properties of regulatory B cells regulating B cell targets.
Qiang Fu, Kang Mi Lee, Guoli Huai, Kevin Deng, Divyansh Agarwal, Christian LeGuern

Am J Transplant· December 2021

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Detection of alloreactive T cells from cryopreserved human peripheral blood mononuclear cells.
Naoki Tanimine, Bryna E Burrell, Kevin Deng, Charles Rickert, Kang Mi Lee, Christian LeGuern

J Immunol Methods· April 2021

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On the elusive TCR specificity of thymic regulatory T cells.
Christian LeGuern, Sharon Germana

Am J Transplant· January 2019

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Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation.
Jose Marino, Mohamed H Babiker-Mohamed, Patrick Crosby-Bertorini, Joshua T Paster, Christian LeGuern

Sci Immunol· July 2016

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Primary vascularization of allografts governs their immunogenicity and susceptibility to tolerogenesis.
Cavit D Kant, Yoshinobu Akiyama, Katsunori Tanaka, Susan Shea, Sarah E Connolly, Christian LeGuern

J Immunol· August 2013

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Regulatory T cells for tolerance therapy: revisiting the concept.
Christian Leguern

Crit Rev Immunol· November 2011

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Intracellular MHC class II controls regulatory tolerance to allogeneic transplants.
Christian LeGuern, Yoshinobu Akiyama, Sharon Germana, Katsunori Tanaka, Luis Fernandez

J Immunol· March 2010

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Tolerogenic property of MHC class I and class II molecules: lessons from a gene therapy approach.
Christian LeGuern

Front Biosci· May 2007

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Switching on immune regulation to prevent graft rejection.
Christian LeGuern

Transplantation· May 2005

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Potential role of major histocompatibility complex class II peptides in regulatory tolerance to vascularized grafts.
Christian LeGuern

Transplantation· January 2004

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Histomorphometric comparison of cardiac allograft vasculopathy in miniature swine.
Stuart L Houser, Isabel M McMorrow, Christian LeGuern, Margaret L Schwarze, Yasuli Fuchimoto

J Heart Lung Transplant· January 2004

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Human Fas-ligand expression on porcine endothelial cells does not protect against xenogeneic natural killer cytotoxicity.
Ulrike B Matter-Reissmann, Kai-Christian Sonntag, Urs O Gilli, Christian Leguern, Mårten K J Schneider

Xenotransplantation· January 2004

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Regulation of T-cell functions by MHC class II self-presentation.
Christian LeGuern

Trends Immunol· December 2003

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Engraftment of quiescent progenitors and conversion to full chimerism after nonmyelosuppressive conditioning and hematopoietic cell transplantation in miniature swine.
Brian Lima, Zachary L Gleit, Andrew M Cameron, Sharon Germana, Michael C Murphy, Christian LeGuern

Biol Blood Marrow Transplant· September 2003

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Expression of MHC class II DQ alpha/beta heterodimers from recombinant polycistronic retroviral genomes.
Hideaki Shimada, Sharon Germana, Hideki Hayashi, David H Sachs, Christian LeGuern

Surg Today· July 2003

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Nonmyeloablative conditioning is sufficient to allow engraftment of EGFP-expressing bone marrow and subsequent acceptance of EGFP-transgenic skin grafts in mice.
Goran Andersson, Ben M W Illigens, Kevin W Johnson, David Calderhead, Christian LeGuern

Blood· June 2003

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