Publications by authors named "Christian Oefner"

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I
Inhibitory properties and X-ray crystallographic study of the binding of AR-101, AR-102 and iclaprim in ternary complexes with NADPH and dihydrofolate reductase from Staphylococcus aureus.
Christian Oefner, Sandro Parisi, Henk Schulz, Sergio Lociuro, Glenn E Dale

Acta Crystallogr D Biol Crystallogr· August 2009

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Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity.
Christian Oefner, Monica Bandera, Andreas Haldimann, Heike Laue, Henk Schulz

J Antimicrob Chemother· April 2009

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Structure of human endothelin-converting enzyme I complexed with phosphoramidon.
Henk Schulz, Glenn E Dale, Yasmin Karimi-Nejad, Christian Oefner

J Mol Biol· January 2009

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Structural studies of a bifunctional inhibitor of neprilysin and DPP-IV.
Christian Oefner, Sabine Pierau, Henk Schulz, Glenn E Dale

Acta Crystallogr D Biol Crystallogr· September 2007

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Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography.
Christian Oefner, Henk Schulz, Allan D'Arcy, Glenn E Dale

Acta Crystallogr D Biol Crystallogr· June 2006

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The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.
Aengus Mac Sweeney, Roland Lange, Roberta P M Fernandes, Henk Schulz, Glenn E Dale, Christian Oefner

J Mol Biol· January 2005

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Structure-based design, synthesis, and in vitro evaluation of nonpeptidic neprilysin inhibitors.
Stefan Sahli, Bernhard Stump, Tobias Welti, Denise Blum-Kaelin, Johannes D Aebi, Christian Oefner

Chembiochem· July 2004

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Crystal structures of Staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate.
Alice Douangamath, Glenn E Dale, Allan D'Arcy, Michael Almstetter, Robert Eckl, Christian Oefner

J Med Chem· March 2004

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Structural analysis of neprilysin with various specific and potent inhibitors.
Christian Oefner, Bernard P Roques, Marie-Claude Fournie-Zaluski, Glenn E Dale

Acta Crystallogr D Biol Crystallogr· February 2004

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The 1.15A crystal structure of the Staphylococcus aureus methionyl-aminopeptidase and complexes with triazole based inhibitors.
Christian Oefner, Alice Douangamath, Allan D'Arcy, Sascha Häfeli, Daniel Mareque

J Mol Biol· September 2003

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High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrolidine.
Christian Oefner, Allan D'Arcy, Aengus Mac Sweeney, Sabine Pierau, Rana Gardiner

Acta Crystallogr D Biol Crystallogr· July 2003

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The protein as a variable in protein crystallization.
Glenn E Dale, Christian Oefner, Allan D'Arcy

J Struct Biol· April 2003

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