Publications by authors named "Christian Pichlo"

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Phenotypic screening converges on CDK9 inhibition as a therapeutic strategy in translocation renal cell carcinoma.
Dharma R Thapa, Riva Deodhar, Adam Skepner, Prathyusha Konda, Meng Zhou, Christian Pichlo

bioRxiv· August 2025

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Phenotypic Discovery of Triazolo[1,5-]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype.
Fabian Wesseler, Stefan Lohmann, Daniel Riege, Jonas Halver, Aileen Roth, Christian Pichlo

J Med Chem· November 2022

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A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family.
Thomas Hermanns, Christian Pichlo, Ulrich Baumann, Kay Hofmann

Nat Commun· January 2022

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Proteasomal degradation induced by DPP9-mediated processing competes with mitochondrial protein import.
Yannik Finger, Markus Habich, Sarah Gerlich, Sophia Urbanczyk, Erik van de Logt, Christian Pichlo

EMBO J· October 2020

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Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis.
Sabine Ruegenberg, Moritz Horn, Christian Pichlo, Kira Allmeroth, Ulrich Baumann

Nat Commun· February 2020

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Molecular determinants of the mechanism and substrate specificity of proline-proline endopeptidase-1.
Christian Pichlo, Linda Juetten, Fabian Wojtalla, Magdalena Schacherl, Dolores Diaz

J Biol Chem· July 2019

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2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach.
Miriam Schehr, Chiara Ianes, Jörn Weisner, Linda Heintze, Matthias P Müller, Christian Pichlo

Photochem Photobiol Sci· June 2019

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Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.
Andreas Luxenburger, Dorian Schmidt, Chiara Ianes, Christian Pichlo, Marc Krüger

Molecules· March 2019

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Heterologous expression and characterization of a novel serine protease from Daphnia magna: A possible role in susceptibility to toxic cyanobacteria.
Jacqueline Lange, Fatih Demir, Pitter F Huesgen, Ulrich Baumann, Eric von Elert, Christian Pichlo

Aquat Toxicol· December 2018

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Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.
Balbina García-Reyes, Lydia Witt, Björn Jansen, Ebru Karasu, Tanja Gehring, Christian Pichlo

J Med Chem· May 2018

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Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer.
Christian Pichlo, Christine Toelzer, Konrad Chojnacki, Sinan Öcal, Matthias Uthoff

Acta Crystallogr F Struct Biol Commun· May 2018

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Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function.
Natalia Mendoza-Ferreira, Marie Coutelier, Eva Janzen, Seyyedmohsen Hosseinibarkooie, Heiko Löhr, Christian Pichlo

Neurol Genet· February 2018

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A family of unconventional deubiquitinases with modular chain specificity determinants.
Thomas Hermanns, Christian Pichlo, Ilka Woiwode, Karsten Klopffleisch, Katharina F Witting

Nat Commun· February 2018

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Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.
Jakob Halekotte, Lydia Witt, Chiara Ianes, Marc Krüger, Mike Bührmann, Christian Pichlo

Molecules· March 2017

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Production, Crystallization and Structure Determination of C. difficile PPEP-1 via Microseeding and Zinc-SAD.
Christian Pichlo, Angelika A Montada, Magdalena Schacherl, Ulrich Baumann

J Vis Exp· December 2016

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Structural Basis of Proline-Proline Peptide Bond Specificity of the Metalloprotease Zmp1 Implicated in Motility of Clostridium difficile.
Magdalena Schacherl, Christian Pichlo, Ines Neundorf, Ulrich Baumann

Structure· September 2015

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