Publications by authors named "Christian Wolfrum"

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Adipose tissue retains an epigenetic memory of obesity after weight loss.
Laura C Hinte, Daniel Castellano-Castillo, Adhideb Ghosh, Kate Melrose, Emanuel Gasser, Falko Noé, Lucas Massier, Hua Dong, Wenfei Sun, Anne Hoffmann

Nature· December 2024

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Short-term feeding of a ketogenic diet induces more severe hepatic insulin resistance than an obesogenic high-fat diet.
Gerald Grandl, Leon Straub, Carla Rudigier, Myrtha Arnold, Stephan Wueest, Daniel Konrad, Christian Wolfrum

J Physiol· October 2018

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Glucagon controls obesity-specific energy expenditure via persistent cAMP/PKA signaling.
Fen Long, Tenagne Delessa Challa, Lianggong Ding, Anand Kumar Sharma, Chunyan Wu, Christian Wolfrum

J Hepatol· December 2025

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Adipose Triglyceride Lipase Knockout Increases Anticontractile Effects of Perivascular Adipose Tissue.
Astrid Schrammel, Gerald Wölkart, Elisabeth Ableitner, Martina Derler, Isabella Potoschnig, Christian Wolfrum

Arterioscler Thromb Vasc Biol· December 2025

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Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo.
Inka Rapöhn, Helen Broghammer, Anne Hoffmann, Kevin Möhlis, Anna Moormann, Christian Wolfrum

Nat Commun· December 2025

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Hepatic GCGR is required for the superior weight loss and metabolic effects of a structurally related analogue of the dual GCGR/GLP-1R agonist survodutide in mice.
Fen Long, Tenagne D Challa, Vissarion Efthymiou, Manuel Klug, Thomas Klein, Christian Wolfrum

Diabetes Obes Metab· December 2025

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Antibiotic-induced gut microbiota depletion enhances glucose tolerance linked to GLP-1 signaling.
Alexandra Kellenberger, Revati Sumukh Dewal, Alice de Wouters d'Oplinter, Andreas Sichert, Markus Heine, Christian Wolfrum

Front Endocrinol (Lausanne)· December 2025

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Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism.
Jérémy Dufau, Emeline Recazens, Laura Bottin, Camille Bergoglio, Aline Mairal, Christian Wolfrum

Cell Metab· November 2025

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Integrative analysis of gene expression and histone modifications for DES, DSP, GJA1 and SMOC2 in adipose tissue reveals potential relationship to cardiometabolic health.
Sadia Saeed, Anne Hoffmann, Stina Ingrid Alice Svensson, Tina Visnovska, Tobias Hagemann, Christian Wolfrum

Mol Med· November 2025

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Regulators of RNA mC methylation are adipose tissue depot-specific expressed and correlate with clinical variables of obesity in humans.
Stina Ingrid Alice Svensson, Anne Hoffmann, Tobias Hagemann, Akin Cayir, Sadia Saeed, Christian Wolfrum

Front Endocrinol (Lausanne)· October 2025

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MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes.
Chunyan Wu, Tongtong Wang, Adhideb Ghosh, Fen Long, Anand Kumar Sharma, Christian Wolfrum

Nat Commun· October 2025

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Age- and sex-specific transcriptomic changes drive the prothrombotic potential of megakaryocytes.
Pratintip Lee, Carolina Balbi, Meret S Allemann, Adhideb Ghosh, Tongtong Wang, Christian Wolfrum

Biomark Res· October 2025

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Secretory kinase FAM20C triggers adipocyte dysfunction inciting insulin resistance and inflammation in obesity.
Ankit Gilani, Benjamin D Stein, Anne Hoffmann, Renan Pereira de Lima, Elizabeth E Ha, Christian Wolfrum

J Clin Invest· October 2025

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Sarcospan, a candidate gene of fat distribution, may affect lipid storage in adipocytes.
Katharina Anastasia Dinter, Samantha Aurich, Luise Müller, Adhideb Ghosh, Falko Noé, Christian Wolfrum

Mol Cell Endocrinol· September 2025

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An epigenome atlas of mouse adipocytes.
Laura C Hinte, Adhideb Ghosh, Daniel Castellano-Castillo, Christian Wolfrum, Ferdinand von Meyenn

Mol Metab· September 2025

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NRAC controls CD36-mediated fatty acid uptake in adipocytes and lipid clearance in vivo.
Inderjeet Singh, Yasuhiro Onogi, Filipe Menezes, Dina Khasanova, Lingru Kang, Christian Wolfrum

EMBO J· September 2025

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Adipocyte-specific deletion of gp130 prevents ketogenic diet-induced hepatic steatosis.
Berkay Senkalfa, Melanie Gloor, Ronja Podlaszewski, Revati S Dewal, Carla Horvath, Christian Wolfrum

Hepatol Commun· September 2025

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Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome.
Ximena Hildebrandt, Önay Veli, Armel Hyoubi, Julia Zinngrebe, Ali T Abdallah, Christian Wolfrum

Sci Adv· September 2025

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A consensus guide to preclinical indirect calorimetry experiments.
Alexander S Banks, David B Allison, Thierry Alquier, Ansarullah, Steven N Austad, Christian Wolfrum

Nat Metab· September 2025

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Deletion of PPARα in mouse brown adipocytes increases their De Novo Lipogenesis.
Pierre-Louis Batrow, Sylvie Caspar-Bauguil, Nathalie Rochet, Nadine Gautier, Anne-Sophie Rousseau, Christian Wolfrum

Mol Metab· August 2025

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The TBLR1/TBL1 Co-Factor Complex Acts as a Transcriptional Checkpoint in the Brown Adipose Tissue Response to Prolonged Cold Exposure.
Sahika Cingir Köker, Foivos-Filippos Tsokanos, Rabih El-Merahbi, Ankush Kumar Jha, Karin Cicatelli, Christian Wolfrum

FASEB J· August 2025

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Genkwanin glycosides are major active compounds in Phaleria nisidai extract mediating improved glucose homeostasis by stimulating glucose uptake into adipose tissues.
Carla Horvath, Joëlle Houriet, Alexandra Kellenberger, Caroline Moser, Lucia Balazova, Christian Wolfrum

Nat Commun· August 2025

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Downregulation of microRNA-494 drives mitochondrial biogenesis and function in trained muscle.
Natália Pálešová, Klára Gabrišová, Jana Babulicová, Patrik Krumpolec, Zuzana Kovaničová, Christian Wolfrum

Exp Physiol· August 2025

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Author Correction: Adipose tissue retains an epigenetic memory of obesity after weight loss.
Laura C Hinte, Daniel Castellano-Castillo, Adhideb Ghosh, Kate Melrose, Emanuel Gasser, Christian Wolfrum

Nature· July 2025

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B cell-derived nociceptin/orphanin FQ contributes to impaired glucose tolerance and insulin resistance in obesity.
Stephanie C Puente-Ruiz, Leona Ide, Julia Schuller, Adel Ben-Kraiem, Anne Hoffmann, Christian Wolfrum

iScience· July 2025

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HOOK1 Gene Expression and DNA Methylation in Obesity and Related Cardiometabolic Traits.
Stina Ingrid Alice Svensson, Sadia Saeed, Anne Hoffmann, Adhideb Ghosh, Christian Wolfrum

Obes Facts· July 2025

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Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution.
Anne Loft, Margo P Emont, Ada Weinstock, Adeline Divoux, Adhideb Ghosh, Christian Wolfrum

Nat Metab· May 2025

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