Publications by authors named "Christiane D Much"

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Calculating Future 10-Year Breast Cancer Risks in Risk-Adapted Surveillance: A Method Comparison and Application in Clinical Practice.
Silke Zachariae, Anne S Quante, Marion Kiechle, Kerstin Rhiem, Tanja N Fehm, Christiane D Much

Cancer Prev Res (Phila)· February 2025

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Cas9-Mediated Nanopore Sequencing Enables Precise Characterization of Structural Variants in Genes.
Dariush Skowronek, Robin A Pilz, Loisa Bonde, Ole J Schamuhn, Janne L Feldmann, Christiane D Much

Int J Mol Sci· December 2022

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Bringing CCM into a dish: cell culture models for cerebral cavernous malformations.
Dariush Skowronek, Robin A Pilz, Konrad Schwefel, Christiane D Much, Ute Felbor

Med Genet· September 2021

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Inactivation of Cerebral Cavernous Malformation Genes Results in Accumulation of von Willebrand Factor and Redistribution of Weibel-Palade Bodies in Endothelial Cells.
Christiane D Much, Barbara S Sendtner, Konrad Schwefel, Eric Freund, Sander Bekeschus

Front Mol Biosci· July 2021

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CRISPR/Cas9-mediated Generation of Human Endothelial Cell Knockout Models of CCM Disease.
Konrad Schwefel, Stefanie Spiegler, Christiane D Much, Ute Felbor, Matthias Rath

Methods Mol Biol· March 2021

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Fibronectin rescues aberrant phenotype of endothelial cells lacking either CCM1, CCM2 or CCM3.
Konrad Schwefel, Stefanie Spiegler, Bettina C Kirchmaier, Patricia K E Dellweg, Christiane D Much

FASEB J· July 2020

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Novel Pathogenic Variants in a Cassette Exon of in Patients With Cerebral Cavernous Malformations.
Christiane D Much, Konrad Schwefel, Dariush Skowronek, Loay Shoubash, Felix von Podewils

Front Neurol· November 2019

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Precise CCM1 gene correction and inactivation in patient-derived endothelial cells: Modeling Knudson's two-hit hypothesis in vitro.
Stefanie Spiegler, Matthias Rath, Christiane D Much, Barbara S Sendtner, Ute Felbor

Mol Genet Genomic Med· July 2019

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Biallelic CCM3 mutations cause a clonogenic survival advantage and endothelial cell stiffening.
Konrad Schwefel, Stefanie Spiegler, Sabine Ameling, Christiane D Much, Robin A Pilz

J Cell Mol Med· March 2019

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