Publications by authors named "Christoph Gerle"

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The Mitochondrial Permeability Transition Pore: Past, Present, and Future.
Michela Carraro, Christoph Gerle, Paolo Bernardi

Annu Rev Biophys· December 2025

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Cryo-EM structure of the ATP11C Q79E mutant reveals the structural basis for altered Phospholipid recognition.
Yuheng Qian, Chai C Gopalasingam, Christoph Gerle, Hideki Shigematsu, Kazuhiro Abe

J Biol Chem· November 2025

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A unique gating mechanism revealed by the cryo-EM structure of monomeric ATP9A flippase.
Kazuhiro Abe, Parthiban Marimuthu, Yuheng Qian, Chai C Gopalasingam, Christoph Gerle

J Biol Chem· October 2025

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Structures of rotary ATP synthase from during proton powered ATP synthesis.
Atsuki Nakano, Jun-Ichi Kishikawa, Nishida Yui, Kyosuke Sugawara, Yuto Kan, Christoph Gerle

Sci Adv· October 2025

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From benchmarking alignment of genome assemblies to IMGT annotation: the paradigm of the bovine Bos taurus T cell receptor (TRG) locus.
Hao Zhou, Chimari Jiko, Christoph Gerle, Marie-Paule Lefranc, Kazutaka Katoh

BMC Genomics· September 2025

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High-resolution cryo-EM analysis visualizes hydrated type I and IV pilus structures from enterotoxigenic Escherichia coli.
Kazuki Kawahara, Hiroya Oki, Minato Iimori, Ryuki Muramoto, Tomoya Imai, Christoph Gerle

Structure· June 2025

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Human F-ATP synthase as a drug target.
Christoph Gerle, Chimari Jiko, Atsuki Nakano, Ken Yokoyama, Chai C Gopalasingam

Pharmacol Res· November 2024

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Corrigendum to "Human F-ATP synthase as a drug target" [Pharmacol. Res. 209 (2024) 107423].
Christoph Gerle, Chimari Jiko, Atsuki Nakano, Ken Yokoyama, Chai C Gopalasingam

Pharmacol Res· November 2024

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N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase.
Gabriele Coluccino, Alessandro Negro, Antonio Filippi, Camilla Bean, Valentina Pia Muraca, Christoph Gerle

Commun Biol· November 2024

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Molecular Structure of the Na,K-ATPase α4β1 Isoform in Its Ouabain-Bound Conformation.
Kazuhiro Abe, Jeff McDermott, Hridya Valia Madapally, Parthiban Marimuthu, Chai C Gopalasingam, Christoph Gerle

Int J Mol Sci· November 2024

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NDT-C11 as a Viable Novel Detergent for Single Particle Cryo-EM.
Chimari Jiko, Jiannan Li, Youngsun Moon, Yoshito Tanaka, Chai C Gopalasingam, Christoph Gerle

Chempluschem· October 2024

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Diatom pyrenoids are encased in a protein shell that enables efficient CO fixation.
Ginga Shimakawa, Manon Demulder, Serena Flori, Akihiro Kawamoto, Yoshinori Tsuji, Christoph Gerle

Cell· October 2024

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Structural insights into thermophilic chaperonin complexes.
Zengwei Liao, Chai C Gopalasingam, Masafumi Kameya, Christoph Gerle, Hideki Shigematsu

Structure· June 2024

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Large-scale column-free purification of bovine F-ATP synthase.
Chimari Jiko, Yukio Morimoto, Tomitake Tsukihara, Christoph Gerle

J Biol Chem· February 2024

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Three structures of PSI-LHCI from Chlamydomonas reinhardtii suggest a resting state re-activated by ferredoxin.
Christoph Gerle, Yuko Misumi, Akihiro Kawamoto, Hideaki Tanaka, Hisako Kubota-Kawai

Biochim Biophys Acta Bioenerg· November 2023

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Deep learning driven de novo drug design based on gastric proton pump structures.
Kazuhiro Abe, Mami Ozako, Miki Inukai, Yoe Matsuyuki, Shinnosuke Kitayama, Christoph Gerle

Commun Biol· September 2023

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Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions.
Paolo Bernardi, Christoph Gerle, Andrew P Halestrap, Elizabeth A Jonas, Jason Karch

Cell Death Differ· August 2023

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Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.
Rebeca Acin-Perez, Cristiane Benincá, Lucia Fernandez Del Rio, Cynthia Shu, Siyouneh Baghdasarian, Christoph Gerle

EMBO J· May 2023

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Rapid and Highly Stable Membrane Reconstitution by LAiR Enables the Study of Physiological Integral Membrane Protein Functions.
Albert Godoy-Hernandez, Amer H Asseri, Aiden J Purugganan, Chimari Jiko, Carol de Ram, Christoph Gerle

ACS Cent Sci· March 2023

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The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation.
Giuseppe Cannino, Andrea Urbani, Marco Gaspari, Mariaconcetta Varano, Alessandro Negro, Christoph Gerle

Cell Death Differ· December 2022

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Structures of multisubunit membrane complexes with the CRYO ARM 200.
Christoph Gerle, Jun-Ichi Kishikawa, Tomoko Yamaguchi, Atsuko Nakanishi, Orkun Çoruh

Microscopy (Oxf)· October 2022

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Structure of cyanobacterial photosystem I complexed with ferredoxin at 1.97 Å resolution.
Jiannan Li, Noriyuki Hamaoka, Fumiaki Makino, Akihiro Kawamoto, Yuxi Lin, Christoph Gerle

Commun Biol· September 2022

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Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump.
Saki Tanaka, Mikio Morita, Tatsuya Yamagishi, Hridya Valia Madapally, Kenichi Hayashida, Christoph Gerle

J Med Chem· June 2022

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Cryo-EM structure of a functional monomeric Photosystem I from Thermosynechococcus elongatus reveals red chlorophyll cluster.
Orkun Çoruh, Anna Frank, Hideaki Tanaka, Akihiro Kawamoto, Eithar El-Mohsnawy, Christoph Gerle

Commun Biol· March 2021

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Mitochondrial F-ATP synthase as the permeability transition pore.
Christoph Gerle

Pharmacol Res· October 2020

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