Publications by authors named "Christoph Springfeld"

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NQO1 as a predictor of response to adjuvant GemCap treatment for pancreatic cancer.
Dylan Williams, Chandni Patel, Kate Murray, Lucy Oldfield, Benjamin Small, Christoph Springfeld

J Natl Cancer Inst· December 2025

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New implications from long-term outcomes of perioperative therapy in resectable pancreatic cancer.
Christoph Springfeld, Thilo Hackert, Daniel H Palmer, Daniel Öhlund, Teresa Peccerella

Br J Cancer· December 2025

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Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling-The CATCH experience.
Mario Hlevnjak, Sabine Heublein, Verena Thewes, Lukas Wagener, Constantin Pixberg, Christoph Springfeld

Int J Cancer· October 2025

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Protocol: Faecal microbiota transfer in liver cancer to overcome resistance to atezolizumab/bevacizumab - a multicentre, randomised, placebo-controlled, double-blind phase II trial (the FLORA trial).
Conrad Rauber, Maria Paula Roberti, Maria Jgt Vehreschild, Anastasia Tsakmaklis, Christoph Springfeld

BMJ Open· September 2025

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A phase III randomized study of first-line NUC-1031/cisplatin vs. gemcitabine/cisplatin in advanced biliary tract cancer.
Jennifer J Knox, Mairéad G McNamara, Igor S Bazin, Do-Youn Oh, Oleksii Zubkov, Christoph Springfeld

J Hepatol· August 2025

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Longitudinal CE-MRI-based Siamese network with machine learning to predict tumor response in HCC after DEB-TACE.
Nan Wei, René Michael Mathy, De-Hua Chang, Philipp Mayer, Jakob Liermann, Christoph Springfeld

Cancer Imaging· August 2025

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Reply to: Adjuvant Treatment Options and Modalities in Pancreatic Adenocarcinoma: Insights From ESPAC4.
Daniel H Palmer, Richard J Jackson, Christoph Springfeld, Thilo Hackert, Christoph W Michalski

J Clin Oncol· July 2025

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De novo induction of tertiary lymphoid structures: an immunotherapeutic strategy in pancreatic cancer.
Azaz Ahmed, Christoph Springfeld, Niels Halama

Signal Transduct Target Ther· May 2025

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Pancreatic Adenocarcinoma: Long-Term Outcomes of Adjuvant Therapy in the ESPAC4 Phase III Trial.
Daniel H Palmer, Richard Jackson, Christoph Springfeld, Paula Ghaneh, Charlotte Rawcliffe

J Clin Oncol· April 2025

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Efficacy of Zenocutuzumab in Fusion-Positive Cancer.
Alison M Schram, Koichi Goto, Dong-Wan Kim, Teresa Macarulla, Antoine Hollebecque, Christoph Springfeld

N Engl J Med· February 2025

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Stereotactic body radiotherapy with carbon ions as local ablative treatment in patients with primary liver cancer.
Paula Hoffmeister-Wittmann, Philipp Hoegen-Saßmannshausen, Livia Wicklein, Fabian Weykamp, Katharina Seidensaal, Christoph Springfeld

Radiat Oncol· February 2025

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Tumour plasticity and tumour microenvironment interactions as potential immunologic targets for pancreatic cancer treatment.
Xu Zhou, Christoph Springfeld, Susanne Roth, Teresa Peccerella, Peter Bailey

Chin Clin Oncol· December 2024

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Lymphotoxin beta-activated LTBR/NIK/RELB axis drives proliferation in cholangiocarcinoma.
Kaiyu Xu, Annika Kessler, Federico Nichetti, Paula Hoffmeister-Wittmann, Anna-Lena Scherr, Christoph Springfeld

Liver Int· November 2024

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Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response.
Jingyu An, Roma Kurilov, Teresa Peccerella, Frank Bergmann, Mouad Edderkaoui, Christoph Springfeld

Transl Oncol· November 2024

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Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCC.
Anna-Lena Scherr, Luisa Nader, Kaiyu Xu, Christin Elssner, Dirk A Ridder, Christoph Springfeld

Hepatology· August 2024

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The phase I/II eNRGy trial: Zenocutuzumab in patients with cancers harboring gene fusions.
Dong-Wan Kim, Alison M Schram, Antoine Hollebecque, Kazumi Nishino, Teresa Macarulla, Christoph Springfeld

Future Oncol· June 2024

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Carbon ion radiotherapy of hepatocellular carcinoma provides excellent local control: The prospective phase I PROMETHEUS trial.
Philipp Hoegen-Saßmannshausen, Patrick Naumann, Paula Hoffmeister-Wittmann, Semi Ben Harrabi, Katharina Seidensaal, Christoph Springfeld

JHEP Rep· June 2024

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ESMO 2023 pancreatic cancer guidelines signal stepwise progress.
Christoph Springfeld, Peter Bailey, Markus W Büchler, John P Neoptolemos

Hepatobiliary Surg Nutr· April 2024

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A phase Ib/II trial of capmatinib plus spartalizumab spartalizumab alone in patients with pretreated hepatocellular carcinoma.
Armando Santoro, Eric Assenat, Thomas Yau, Jean-Pierre Delord, Michela Maur, Christoph Springfeld

JHEP Rep· April 2024

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Durvalumab Plus Gemcitabine and Cisplatin in Patients with Advanced Biliary Tract Cancer: An Exploratory Analysis of Real-World Data.
Alexander Olkus, Aurelie Tomczak, Anne Katrin Berger, Conrad Rauber, Philip Puchas, Christoph Springfeld

Target Oncol· March 2024

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Repotrectinib in Fusion-Positive Non-Small-Cell Lung Cancer.
Alexander Drilon, D Ross Camidge, Jessica J Lin, Sang-We Kim, Benjamin J Solomon, Christoph Springfeld

N Engl J Med· January 2024

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Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy.
Nicolas Hohmann, Martin Ronald Sprick, Moritz Pohl, Azaz Ahmed, Jürgen Burhenne, Christoph Springfeld

Clin Transl Sci· December 2023

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Promising Outcomes of Modified ALPPS for Staged Hepatectomy in Cholangiocarcinoma.
Arianeb Mehrabi, Mohammad Golriz, Ali Ramouz, Elias Khajeh, Ahmed Hammad, Christoph Springfeld

Cancers (Basel)· November 2023

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Association of perioperative use of statins, metformin, and aspirin with recurrence after curative liver resection in patients with hepatocellular carcinoma: A propensity score matching analysis.
Elias Khajeh, Ehsan Aminizadeh, Arash Dooghaie Moghadam, Ali Ramouz, Rosa Klotz, Christoph Springfeld

Cancer Med· October 2023

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Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC.
Xu Zhou, Jingyu An, Roma Kurilov, Benedikt Brors, Kai Hu, Christoph Springfeld

Nat Cancer· September 2023

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