Publications by authors named "Christophe Le Clorennec"

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Correction: The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation.
Christophe Le Clorennec, Yassamine Lazrek, Olivier Dubreuil, Christel Larbouret, Marie-Alix Poul

Oncotarget· October 2024

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UBE4B interacts with the ITCH E3 ubiquitin ligase to induce Ku70 and c-FLIPL polyubiquitination and enhanced neuroblastoma apoptosis.
Christophe Le Clorennec, Divya Subramonian, Yuchen Huo, Peter E Zage

Cell Death Dis· November 2023

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USP7 Inhibition Suppresses Neuroblastoma Growth via Induction of p53-Mediated Apoptosis and EZH2 and N-Myc Downregulation.
Christophe Le Clorennec, Karen Lee, Yuchen Huo, Peter E Zage

Int J Mol Sci· September 2023

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Identification of a novel gene signature for neuroblastoma differentiation using a Boolean implication network.
Peter E Zage, Yuchen Huo, Divya Subramonian, Christophe Le Clorennec, Pradipta Ghosh

Genes Chromosomes Cancer· June 2023

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ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells.
Christophe Le Clorennec, Yassamine Lazrek, Olivier Dubreuil, Carla Sampaio, Christel Larbouret

Cell Commun Signal· August 2019

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Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3.
Christophe Le Clorennec, Hervé Bazin, Olivier Dubreuil, Christel Larbouret, Charline Ogier

Mol Cancer Ther· July 2017

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The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation.
Christophe Le Clorennec, Yassamine Lazrek, Olivier Dubreuil, Christel Larbouret, Marie-Alix Poul

Oncotarget· June 2016

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Anti-HER3 domain 1 and 3 antibodies reduce tumor growth by hindering HER2/HER3 dimerization and AKT-induced MDM2, XIAP, and FoxO1 phosphorylation.
Yassamine Lazrek, Olivier Dubreuil, Véronique Garambois, Nadège Gaborit, Christel Larbouret, Christophe Le Clorennec

Neoplasia· March 2013

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Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway.
Nathalie Faumont, Christophe Le Clorennec, Pierre Teira, Gauthier Goormachtigh, Jean Coll

Cancer Res· June 2009

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Molecular basis of cytotoxicity of Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) in EBV latency III B cells: LMP1 induces type II ligand-independent autoactivation of CD95/Fas with caspase 8-mediated apoptosis.
Christophe Le Clorennec, Tan-Sothéa Ouk, Ibtissam Youlyouz-Marfak, Stéphanie Panteix, Catherine-Claude Martin

J Virol· July 2008

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Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways.
Gautier Goormachtigh, Tan-Sothéa Ouk, Alexandra Mougel, Denis Tranchand-Bunel, Eric Masy, Christophe Le Clorennec

J Virol· August 2006

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EBV latency III immortalization program sensitizes B cells to induction of CD95-mediated apoptosis via LMP1: role of NF-kappaB, STAT1, and p53.
Christophe Le Clorennec, Ibtissam Youlyouz-Marfak, Eric Adriaenssens, Jean Coll, Georg W Bornkamm

Blood· March 2006

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Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells.
Imen Najjar, Fanny Baran-Marszak, Christophe Le Clorennec, Christelle Laguillier, Olivier Schischmanoff

J Virol· April 2005

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Indolent lymphoplasmacytic and marginal zone B-cell lymphomas: absence of both IRF4 and Ki67 expression identifies a better prognosis subgroup.
Barbara Petit, Marie-Pierre Chaury, Christophe Le Clorennec, Arnaud Jaccard, Nathalie Gachard

Haematologica· February 2005

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Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells.
Fanny Baran-Marszak, Jean Feuillard, Imen Najjar, Christophe Le Clorennec, Jean-Marie Béchet

Blood· October 2004

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