Publications by authors named "Christophe Redon"

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Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer.
Christopher W Schultz, Sourav Saha, Anjali Dhall, Yang Zhang, Parth Desai, Christophe Redon

Proc Natl Acad Sci U S A· October 2025

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Tumor-targeted top1 inhibitor delivery with optimized parp inhibition in advanced solid tumors: a phase i trial of gapped scheduling.
Anish Thomas, Nobuyuki Takahashi, Lenka Oplustil O'Connor, Christophe E Redon, Chirayu Mohindroo

Nat Commun· October 2025

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NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING.
Yoo Sun Kim, Barzin Y Nabet, Briana N Cortez, Nai-Yun Sun, Robin Sebastian, Christophe E Redon

J Clin Invest· September 2025

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Bimodal Genomic Approach Predicting Semaphorin 7A (SEMA7A) as Prognostic Biomarker in Adrenocortical Carcinoma.
Anjali Dhall, Daiki Taniyama, Fathi Elloumi, Augustin Luna, Sudhir Varma, Christophe E Redon

Cancers (Basel)· June 2025

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Selective interactions at pre-replication complexes categorize baseline and dormant origins.
Bhushan L Thakur, Christophe E Redon, Haiqing Fu, Robin Sebastian, Nana A Kusi

Nat Commun· May 2025

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Lamin A/C Deficiency Drives Genomic Instability and Poor Survival in Small-Cell Lung Cancer through Increased R-loop Accumulation.
Christopher W Schultz, Sourav Saha, Anjali Dhall, Yang Zhang, Parth Desai, Christophe Redon

bioRxiv· May 2025

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Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma.
Anjali Dhall, Daiki Taniyama, Fathi Elloumi, Augustin Luna, Sudhir Varma, Christophe E Redon

bioRxiv· April 2025

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Mechanism for local attenuation of DNA replication at double-strand breaks.
Robin Sebastian, Eric G Sun, Michael Fedkenheuer, Haiqing Fu, SeolKyoung Jung, Christophe E Redon

Nature· March 2025

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Metastatic organotropism in small cell lung cancer.
Manan Krishnamurthy, Anjali Dhall, Sarthak Sahoo, Christopher W Schultz, Michelle A Baird, Christophe Redon

bioRxiv· January 2025

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RepID as a potential biomarker and therapeutic target for lung neuroendocrine tumor.
Jong-Uk Park, Jae-Hyun Jo, Sangjune Kim, Christophe E Redon, Mirit I Aladjem

Sci Rep· November 2024

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Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRPM4.
Makito Mizunuma, Christophe E Redon, Liton Kumar Saha, Andy D Tran, Anjali Dhall

Cancer Res Commun· August 2024

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Berzosertib Plus Topotecan vs Topotecan Alone in Patients With Relapsed Small Cell Lung Cancer: A Randomized Clinical Trial.
Nobuyuki Takahashi, Zhonglin Hao, Liza C Villaruz, Jun Zhang, Jimmy Ruiz, Christophe E Redon

JAMA Oncol· December 2023

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SIRT1 Prevents R-Loops during Chronological Aging by Modulating DNA Replication at rDNA Loci.
Bhushan L Thakur, Nana A Kusi, Sara Mosavarpour, Roger Zhu, Christophe E Redon

Cells· November 2023

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Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial.
Melissa L Abel, Nobuyuki Takahashi, Cody Peer, Christophe E Redon, Samantha Nichols

Clin Cancer Res· September 2023

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Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication.
Junko Murai, Michele Ceribelli, Haiqing Fu, Christophe E Redon, Ukhyun Jo

Mol Cancer Ther· August 2023

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RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter.
Jae-Hyun Jo, Jong-Uk Park, Yeong-Mu Kim, Seon-Mi Ok, Dong-Kyu Kim, Christophe E Redon

Cell Commun Signal· August 2023

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RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter.
Jae-Hyun Jo, Seon-Mi Ok, Dong-Kyu Kim, Yeong-Mu Kim, Jong-Uk Park, Christophe E Redon

Res Sq· June 2023

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Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.
Lőrinc Sándor Pongor, Christopher W Schultz, Lorenzo Rinaldi, Darawalee Wangsa, Christophe E Redon

Cancer Discov· April 2023

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The differentially expressed gene signatures of the Cullin 3-RING ubiquitin ligases in neuroendocrine cancer.
Jong-Uk Park, Dong-Kyu Kim, Ji-Ye Kim, Jae-Hyun Jo, Yeong-Mu Kim, Christophe E Redon

Biochem Biophys Res Commun· December 2022

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Replication stress defines distinct molecular subtypes across cancers.
Nobuyuki Takahashi, Sehyun Kim, Christopher W Schultz, Vinodh N Rajapakse, Yang Zhang, Christophe E Redon

Cancer Res Commun· June 2022

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Convergence of SIRT1 and ATR signaling to modulate replication origin dormancy.
Bhushan L Thakur, Adrian M Baris, Haiqing Fu, Christophe E Redon, Lorinc S Pongor

Nucleic Acids Res· May 2022

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BEND3 safeguards pluripotency by repressing differentiation-associated genes.
Fredy Kurniawan, Neha Chetlangia, Mohammad Kamran, Christophe E Redon, Lorinc Pongor

Proc Natl Acad Sci U S A· March 2022

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Preventing excess replication origin activation to ensure genome stability.
Bhushan L Thakur, Anagh Ray, Christophe E Redon, Mirit I Aladjem

Trends Genet· February 2022

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BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.
Zhihua Kang, Pan Fu, Allen L Alcivar, Haiqing Fu, Christophe Redon

Nat Commun· October 2021

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Histone Variant H2A.J Is Enriched in Luminal Epithelial Gland Cells.
Christophe E Redon, Zoe Schmal, Gargi Tewary, Adèle Mangelinck, Régis Courbeyrette

Genes (Basel)· October 2021

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