Publications by authors named "Christopher A MacRaild"

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Validation of solvent proteome profiling for antimalarial drug target deconvolution.
Yijia Ji, Joshua P Morrow, Christopher A MacRaild, Haijian Zhang, Carlo Giannangelo

Int J Parasitol Drugs Drug Resist· December 2025

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Novel heterospirocyclic antimalarials with activity against artemisinin- and multidrug-resistant P. falciparum malaria.
Liana Theodoridis, Carlo Giannangelo, Farrah El-Saafin, Mr Ranga Prabhath, Christopher A Macraild

Int J Parasitol Drugs Drug Resist· December 2025

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Alba protein-mediated gene and protein regulation in protozoan parasites.
Meghan E Zadow, Christopher A MacRaild, Darren J Creek, Danny W Wilson

Int J Parasitol· September 2025

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Optimization and Characterization of N-Acetamide Indoles as Antimalarials That Target PfATP4.
Jon Kyle Awalt, Zi Kang Ooi, Trent D Ashton, Mahta Mansouri, Petar P S Calic, Christopher A MacRaild

J Med Chem· April 2025

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Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4.
Trent D Ashton, Petar P S Calic, Madeline G Dans, Zi Kang Ooi, Qingmiao Zhou, Christopher A MacRaild

J Med Chem· August 2024

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Systematic Down-Selection of Repurposed Drug Candidates for COVID-19.
Christopher A MacRaild, Muzaffar-Ur-Rehman Mohammed, Faheem, Sankaranarayanan Murugesan, Ian K Styles

Int J Mol Sci· October 2022

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Use of Human Lung Tissue Models for Screening of Drugs against SARS-CoV-2 Infection.
Alexander J McAuley, Petrus Jansen van Vuren, Muzaffar-Ur-Rehman Mohammed, Faheem, Sarah Goldie, Christopher A MacRaild

Viruses· October 2022

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Genetic and chemical validation of aminopeptidase A-M17 as a drug target in the hemoglobin digestion pathway.
Rebecca C S Edgar, Ghizal Siddiqui, Katheryn Hjerrild, Tess R Malcolm, Natalie B Vinh, Christopher A MacRaild

Elife· September 2022

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A new mass spectral library for high-coverage and reproducible analysis of the Plasmodium falciparum-infected red blood cell proteome.
Ghizal Siddiqui, Amanda De Paoli, Christopher A MacRaild, Anna E Sexton, Coralie Boulet

Gigascience· March 2022

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Peroxide Antimalarial Drugs Target Redox Homeostasis in Infected Red Blood Cells.
Ghizal Siddiqui, Carlo Giannangelo, Amanda De Paoli, Anna Katharina Schuh, Kim C Heimsch, Christopher A MacRaild

ACS Infect Dis· January 2022

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Discovery and development of 2-aminobenzimidazoles as potent antimalarials.
Shane M Devine, Matthew P Challis, Jomo K Kigotho, Ghizal Siddiqui, Amanda De Paoli, Christopher A MacRaild

Eur J Med Chem· October 2021

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Guiding the Immune Response to a Conserved Epitope in MSP2, an Intrinsically Disordered Malaria Vaccine Candidate.
Jeffrey Seow, Sreedam C Das, Rodrigo A V Morales, Ricardo Ataide, Bankala Krishnarjuna, Christopher A MacRaild

Vaccines (Basel)· August 2021

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Liposome engraftment and antigen combination potentiate the immune response towards conserved epitopes of the malaria vaccine candidate MSP2.
Sreedam C Das, Jason D Price, Katharine Gosling, Nicola MacLennan, Ricardo Ataíde, Christopher A MacRaild

Vaccine· March 2021

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Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.
Alessia Belgi, James V Burnley, Christopher A MacRaild, Sandeep Chhabra, Khaled A Elnahriry

J Med Chem· March 2021

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Merozoite surface protein 2 adsorbed onto acetalated dextran microparticles for malaria vaccination.
Rebeca T Stiepel, Cole J Batty, Christopher A MacRaild, Raymond S Norton, Eric Bachelder

Int J Pharm· January 2021

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A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Xiaochun Xiong, John G Menting, Maria M Disotuar, Nicholas A Smith, Carlie A Delaine, Christopher A MacRaild

Nat Struct Mol Biol· July 2020

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Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Xiaochun Xiong, John G Menting, Maria M Disotuar, Nicholas A Smith, Carlie A Delaine, Christopher A MacRaild

Nat Struct Mol Biol· July 2020

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Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa.
Khaled A Elnahriry, Dorothy C C Wai, Bankala Krishnarjuna, Noha N Badawy, Balasubramanyam Chittoor, Christopher A MacRaild

Toxicon· October 2019

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Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
Mansura Akter, Nyssa Drinkwater, Shane M Devine, Simon C Drew, Bankala Krishnarjuna, Christopher A MacRaild

ChemMedChem· March 2019

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Interaction of merozoite surface protein 2 with lipid membranes.
Chenghui Lu, Xue Zheng, Wei Zhang, Hongxin Zhao, Christopher A MacRaild

FEBS Lett· February 2019

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Modulation of the aggregation of an amyloidogenic sequence by flanking-disordered region in the intrinsically disordered antigen merozoite surface protein 2.
Wei Zhang, Jiahai Zhang, Christopher A MacRaild, Raymond S Norton, Robin F Anders

Eur Biophys J· January 2019

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Probing the correlation between insulin activity and structural stability through introduction of the rigid A6-A11 bond.
Shee Chee Ong, Alessia Belgi, Bianca van Lierop, Carlie Delaine, Sofianos Andrikopoulos, Christopher A MacRaild

J Biol Chem· July 2018

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Disordered epitopes as peptide vaccines.
Christopher A MacRaild, Jeffrey Seow, Sreedam C Das, Raymond S Norton

Pept Sci (Hoboken)· May 2018

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Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope.
Bankala Krishnarjuna, Toshihiko Sugiki, Rodrigo A V Morales, Jeffrey Seow, Toshimichi Fujiwara, Christopher A MacRaild

Commun Biol· May 2018

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Corrigendum to "Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK" [Peptides 99 (2018) 169-178].
Bankala Krishnarjuna, Christopher A MacRaild, Punnepalli Sunanda, Rodrigo A V Morales, Steve Peigneur

Peptides· March 2018

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