Publications by authors named "Christopher A Pohl"

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The current state-of-the-art approaches and emerging opportunities for hydrophobic interaction chromatography for the characterization of intact proteins and biotherapeutics.
Sebastiaan Eeltink, Raphael Ewonde Ewonde, Daniel Papp, Quang-Dong Bui, Ken Broeckhoven, Christopher A Pohl

J Chromatogr A· August 2025

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Mitigating the effects of organic solvents in sample diluents for ion chromatography: A comprehensive study and guidelines for optimization.
Mingwan Leng, Frank Bernardoni, Heather Wang, Sachin Lohani, Erik L Regalado, Christopher A Pohl

J Chromatogr A· July 2025

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Universal ion chromatography method for anions in active pharmaceutical ingredients enabled by computer-assisted separation modeling.
Tianyu Yuan, Dolee Merai, Matthew J Gunsch, Ryan Peters, Sachin Lohani, Christopher A Pohl

J Pharm Biomed Anal· April 2024

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Selectivity and Resolving Power of Hydrophobic Interaction Chromatography Targeting the Separation of Monoclonal Antibody Variants.
Raphael Ewonde Ewonde, Katharina Böttinger, Jelle De Vos, Nico Lingg, Alois Jungbauer, Christopher A Pohl

Anal Chem· January 2024

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Hybrid grafted and hyperbranched anion exchangers for ion chromatography.
Alexandra V Zatirakha, Christopher A Pohl

J Chromatogr A· September 2023

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A Universal Eluent System for Method Scouting and Separation of Biotherapeutic Proteins by Ion-Exchange, Size-Exclusion, and Hydrophobic Interaction Chromatography.
Alexander B Schwahn, Julia Baek, Shanhua Lin, Christopher A Pohl, Ken Cook

Anal Chem· November 2022

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Preparation of ion exchange columns with longitudinal stationary phase gradients.
Christopher A Pohl

Heliyon· May 2021

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New Insights into the Chromatography Mechanisms of Ion-Exchange Charge Variant Analysis: Dispelling Myths and Providing Guidance for Robust Method Optimization.
Julia Baek, Alexander B Schwahn, Shanhua Lin, Christopher A Pohl, Mauro De Pra

Anal Chem· October 2020

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Localised quantitative structure-retention relationship modelling for rapid method development in reversed-phase high performance liquid chromatography.
Soo Hyun Park, Mauro De Pra, Paul R Haddad, Sylvia Grosse, Christopher A Pohl

J Chromatogr A· January 2020

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Ultra-High-Pressure Ion Chromatography with Suppressed Conductivity Detection at 70 MPa Using Columns Packed with 2.5 μm Anion-Exchange Particles.
Sam Wouters, José Luís Dores-Sousa, Yan Liu, Christopher A Pohl, Sebastiaan Eeltink

Anal Chem· November 2019

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Retention prediction using quantitative structure-retention relationships combined with the hydrophobic subtraction model in reversed-phase liquid chromatography.
Yabin Wen, Ruth I J Amos, Mohammad Talebi, Roman Szucs, John W Dolan, Christopher A Pohl

Electrophoresis· September 2019

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A new suppressor design for low noise performance with carbonate eluents for Ion Chromatography.
Kannan Srinivasan, Brittany K Omphroy, Rong Lin, Christopher A Pohl

Talanta· October 2018

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Retention Index Prediction Using Quantitative Structure-Retention Relationships for Improving Structure Identification in Nontargeted Metabolomics.
Yabin Wen, Ruth I J Amos, Mohammad Talebi, Roman Szucs, John W Dolan, Christopher A Pohl

Anal Chem· August 2018

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Electrostatically attached highly branched anion-exchange phases derived from diamines and diepoxides.
Christopher A Pohl, Kannan Srinivasan

Talanta· July 2018

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Ion exchange column capacities. Predicting retention behavior of open tubular columns coated with the same phase.
Weixiong Huang, Christopher A Pohl, Purnendu K Dasgupta

J Chromatogr A· May 2018

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Retention prediction in reversed phase high performance liquid chromatography using quantitative structure-retention relationships applied to the Hydrophobic Subtraction Model.
Yabin Wen, Mohammad Talebi, Ruth I J Amos, Roman Szucs, John W Dolan, Christopher A Pohl

J Chromatogr A· March 2018

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Chemometric-assisted method development in hydrophilic interaction liquid chromatography: A review.
Maryam Taraji, Paul R Haddad, Ruth I J Amos, Mohammad Talebi, Roman Szucs, Christopher A Pohl

Anal Chim Acta· February 2018

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Novel method for manipulation of anion-exchange selectivity by derivatizing hydroxyl groups in the proximity of quaternary nitrogen ion-exchange sites with glycidol.
Christopher A Pohl

Talanta· January 2018

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Towards a chromatographic similarity index to establish localised quantitative structure-retention relationships for retention prediction. II Use of Tanimoto similarity index in ion chromatography.
Soo Hyun Park, Mohammad Talebi, Ruth I J Amos, Eva Tyteca, Paul R Haddad, Christopher A Pohl

J Chromatogr A· November 2017

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Benchmarking of Computational Methods for Creation of Retention Models in Quantitative Structure-Retention Relationships Studies.
Ruth I J Amos, Eva Tyteca, Mohammad Talebi, Paul R Haddad, Roman Szucs, Christopher A Pohl

J Chem Inf Model· November 2017

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Error measures in quantitative structure-retention relationships studies.
Maryam Taraji, Paul R Haddad, Ruth I J Amos, Mohammad Talebi, Roman Szucs, Christopher A Pohl

J Chromatogr A· November 2017

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Towards a chromatographic similarity index to establish localised Quantitative Structure-Retention Relationships for retention prediction. III Combination of Tanimoto similarity index, logP, and retention factor ratio to identify optimal analyte training sets for ion chromatography.
Soo Hyun Park, Paul R Haddad, Ruth I J Amos, Mohammad Talebi, Roman Szucs, Christopher A Pohl

J Chromatogr A· October 2017

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Use of dual-filtering to create training sets leading to improved accuracy in quantitative structure-retention relationships modelling for hydrophilic interaction liquid chromatographic systems.
Maryam Taraji, Paul R Haddad, Ruth I J Amos, Mohammad Talebi, Roman Szucs, Christopher A Pohl

J Chromatogr A· July 2017

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Prediction of retention in hydrophilic interaction liquid chromatography using solute molecular descriptors based on chemical structures.
Maryam Taraji, Paul R Haddad, Ruth I J Amos, Mohammad Talebi, Roman Szucs, Christopher A Pohl

J Chromatogr A· February 2017

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Retention prediction of low molecular weight anions in ion chromatography based on quantitative structure-retention relationships applied to the linear solvent strength model.
Soo Hyun Park, Paul R Haddad, Mohammad Talebi, Eva Tyteca, Ruth I J Amos, Christopher A Pohl

J Chromatogr A· February 2017

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