Publications by authors named "Christopher A Rajkumar"

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N-of-1 Trial of Angina Verification Before Percutaneous Coronary Intervention.
Christopher A Rajkumar, Michael J Foley, Fiyyaz Ahmed-Jushuf, Florentina A Simader, Muhammad Mohsin, Sashiananthan Ganesananthan, Alexandra N Nowbar, Shayna Chotai, Sayan Sen, Ricardo Petraco

July 2024

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A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina.
Christopher A Rajkumar, Michael J Foley, Fiyyaz Ahmed-Jushuf, Alexandra N Nowbar, Florentina A Simader, John R Davies, Peter D O'Kane, Peter Haworth, Helen Routledge, Tushar Kotecha

N Engl J Med· December 2023

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Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No Treatment.
James P Howard, Frances A Wood, Judith A Finegold, Alexandra N Nowbar, David M Thompson, Ahran D Arnold, Christopher A Rajkumar, Susan Connolly, Jaimini Cegla, Chris Stride

J Am Coll Cardiol· September 2021

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N-of-1 Trial of a Statin, Placebo, or No Treatment to Assess Side Effects.
Frances A Wood, James P Howard, Judith A Finegold, Alexandra N Nowbar, David M Thompson, Ahran D Arnold, Christopher A Rajkumar, Susan Connolly, Jaimini Cegla, Chris Stride

N Engl J Med· November 2020

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'Faith Healing' and 'Subtraction Anxiety' in Unblinded Trials of Procedures: Lessons from DEFER and FAME-2 for End Points in the ISCHEMIA Trial.
Christopher A Rajkumar, Sukhjinder S Nijjer, Graham D Cole, Rasha Al-Lamee, Darrel P Francis

Circ Cardiovasc Qual Outcomes· March 2018

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The Role of the Collateral Circulation in Stable Angina: An Invasive Placebo-Controlled Study.
Christopher A Rajkumar, Michael J Foley, Fiyyaz Ahmed-Jushuf, Shayna Chotai, Florentina A Simader

Circulation· December 2025

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Reproducibility, Accuracy, and Treatment Impact of Ischemia Severity Assessment From Coronary Angiography　- An ORBITA Study Analysis.
Masafumi Nakayama, Michael Foley, Christopher A Rajkumar, James P Howard, Darrel P Francis

Circ Rep· November 2025

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Microbubble Contrast Agent Use During Invasive Coronary Microvascular Assessment.
Rahul Bahl, Samay Mehta, Henry Seligman, Christopher A Rajkumar, Suraya Gafore

J Soc Cardiovasc Angiogr Interv· October 2025

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Safety, Efficacy, and Effectiveness of Coronary Sinus Reducer Implantation in Refractory Angina: A Meta-Analysis.
Utkarsh Ojha, Muhammad Mohsin, Krzysztof Macierzanka, Fiyyaz Ahmed-Jushuf, Christopher A Rajkumar

JACC Cardiovasc Interv· August 2025

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Ischemia on Dobutamine Stress Echocardiography Predicts Efficacy of PCI: Results From the ORBITA-2 Trial.
Fiyyaz Ahmed-Jushuf, Michael J Foley, Christopher A Rajkumar, Shayna Chotai, Florentina A Simader

J Am Coll Cardiol· May 2025

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Redefining the Rules of Revascularization: Lessons From ISCHEMIA for the Future of Appropriate Use Criteria.
Christopher A Rajkumar

Circ Cardiovasc Qual Outcomes· March 2025

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Fractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Coronary Artery Disease.
Michael J Foley, Christopher A Rajkumar, Fiyyaz Ahmed-Jushuf, Florentina Simader, Shayna Chotai

Circulation· January 2025

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A systematic review of enrolment criteria and treatment efficacy for microvascular angina.
Matthew Hammond-Haley, Kayla Chiew, Fiyyaz Ahmed-Jushuf, Christopher A Rajkumar, Michael J Foley

EuroIntervention· January 2025

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REPLY: Let Us Focus on Angina Mechanisms in Many, Not Just Typical Symptoms in a Few.
Christopher A Rajkumar, Rasha K Al-Lamee

J Am Coll Cardiol· November 2024

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Do Current Clinical Guidelines Set Percutaneous Coronary Intervention Up to Fail? Insights From the ORBITA-2 Trial.
Christopher A Rajkumar, Rasha K Al-Lamee

Circ Cardiovasc Qual Outcomes· September 2024

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Placebo Control and Blinding in Randomized Trials of Procedural Interventions: A Systematic Review and Meta-Regression.
Christopher A Rajkumar, Katharine E Thomas, Michael Foley, Sashiananthan Ganesananthan, Holli Evans

JAMA Surg· July 2024

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Symptoms as a Predictor of the Placebo-Controlled Efficacy of PCI in Stable Coronary Artery Disease.
Florentina A Simader, Christopher A Rajkumar, Michael J Foley, Fiyyaz Ahmed-Jushuf, Shayna Chotai

J Am Coll Cardiol· July 2024

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Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial.
Michael J Foley, Christopher A Rajkumar, Fiyyaz Ahmed-Jushuf, Florentina A Simader, Shayna Chotai

Lancet· April 2024

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Why Does a Cardiologist Believe in a Therapy? The Role of Intuitiveness and Understanding the Mechanism.
Michael J Foley, Christopher A Rajkumar, Fiyyaz Ahmed-Jushuf, Alexandra N Nowbar, Florentina Simader

Circ Cardiovasc Qual Outcomes· March 2024

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A Placebo-Controlled Trial of PCI for Stable Angina. Reply.
Rasha K Al-Lamee, Christopher A Rajkumar

N Engl J Med· March 2024

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The ability of contemporary cardiologists to judge the ischemic impact of a coronary lesion visually.
Michael Foley, Christopher A Rajkumar, Fiyyaz Ahmed-Jushuf, Daniel Nour, Chi Ho Fung

Cardiovasc Revasc Med· February 2024

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A double-blind, randomised, placebo-controlled trial of the coronary sinus Reducer in refractory angina: design and rationale of the ORBITA-COSMIC trial.
Michael J Foley, Christopher A Rajkumar, Fiyyaz Ahmed-Jushuf, Florentina Simader, Rachel H Pathimagaraj

EuroIntervention· February 2024

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Development of artificial intelligence tools for invasive Doppler-based coronary microvascular assessment.
Henry Seligman, Sapna B Patel, Anissa Alloula, James P Howard, Christopher M Cook, Christopher A Rajkumar

Eur Heart J Digit Health· August 2023

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Remote digital smart device follow-up in prospective clinical trials: early insights from ORBITA-2, ORBITA-COSMIC, and ORBITA-STAR.
Sashiananthan Ganesananthan, Christopher A Rajkumar, Michael Foley, Darrel Francis, Rasha Al-Lamee

Eur Heart J Suppl· November 2022

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Cardiopulmonary exercise testing and efficacy of percutaneous coronary intervention: a substudy of the ORBITA trial.
Sashiananthan Ganesananthan, Christopher A Rajkumar, Michael Foley, David Thompson, Alexandra N Nowbar

Eur Heart J· September 2022

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Revascularization in stable coronary artery disease.
Rasha K Al-Lamee, Michael Foley, Christopher A Rajkumar, Darrel P Francis

BMJ· June 2022

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Association Between High-Sensitivity Cardiac Troponin, Myocardial Ischemia, and Revascularization in Stable Coronary Artery Disease.
Christopher A Rajkumar, Ryan Wereski, William Parsonage, Louise Cullen, Ramzi Khamis

J Am Coll Cardiol· May 2022

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Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis.
Mihir A Kelshiker, Henry Seligman, James P Howard, Haseeb Rahman, Michael Foley, Christopher A Rajkumar

Eur Heart J· April 2022

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