Publications by authors named "Christopher Bachran"

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Sortase-A mediated chemoenzymatic lipidation of single-domain antibodies for cell membrane engineering.
Steffen Wöll, Christopher Bachran, Stefan Schiller, Lee Kim Swee, Regina Scherließ

Eur J Pharm Biopharm· August 2020

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Sortagging of liposomes with a murine CD11b-specific VHH increases in vitro and in vivo targeting specificity of myeloid cells.
Steffen Wöll, Christopher Bachran, Stefan Schiller, Matthias Schröder, Lena Conrad

Eur J Pharm Biopharm· January 2019

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Sortaggable liposomes: Evaluation of reaction conditions for single-domain antibody conjugation by Sortase-A and targeting of CD11b myeloid cells.
Steffen Wöll, Christopher Bachran, Stefan Schiller, Matthias Schröder, Lena Conrad

Eur J Pharm Biopharm· December 2018

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Genetic screen in myeloid cells identifies TNF-α autocrine secretion as a factor increasing MDSC suppressive activity via Nos2 up-regulation.
Matthias Schröder, Marit Krötschel, Lena Conrad, Svenja Kerstin Naumann, Christopher Bachran

Sci Rep· September 2018

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Pentaglycine lipid derivates - rp-HPLC analytics for bioorthogonal anchor molecules in targeted, multiple-composite liposomal drug delivery systems.
Steffen Wöll, Stefan Schiller, Christopher Bachran, Lee Kim Swee, Regina Scherließ

Int J Pharm· August 2018

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The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent.
Christopher Bachran, Matthias Schröder, Lena Conrad, Juan J Cragnolini, Fikadu G Tafesse

Sci Rep· December 2017

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Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical screening.
Matthias Schröder, Simone Loos, Svenja Kerstin Naumann, Christopher Bachran, Marit Krötschel

Oncoimmunology· November 2016

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Tumor Targeting and Drug Delivery by Anthrax Toxin.
Christopher Bachran, Stephen H Leppla

Toxins (Basel)· July 2016

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Triterpenoid saponin augmention of saporin-based immunotoxin cytotoxicity for human leukaemia and lymphoma cells is partially immunospecific and target molecule dependent.
Suzanne E Holmes, Christopher Bachran, Hendrik Fuchs, Alexander Weng, Matthias F Melzig

Immunopharmacol Immunotoxicol· February 2015

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Reductive methylation and mutation of an anthrax toxin fusion protein modulates its stability and cytotoxicity.
Christopher Bachran, Pradeep K Gupta, Silke Bachran, Clinton E Leysath, Benjamin Hoover

Sci Rep· April 2014

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Anthrax toxin-mediated delivery of the Pseudomonas exotoxin A enzymatic domain to the cytosol of tumor cells via cleavable ubiquitin fusions.
Christopher Bachran, Thomas Morley, Suzanne Abdelazim, Rasem J Fattah, Shihui Liu

mBio· April 2013

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Recombinant expression and purification of a tumor-targeted toxin in Bacillus anthracis.
Christopher Bachran, Suzanne Abdelazim, Rasem J Fattah, Shihui Liu, Stephen H Leppla

Biochem Biophys Res Commun· January 2013

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Targeted tumor therapy with a fusion protein of an antiangiogenic human recombinant scFv and yeast cytosine deaminase.
Nicole Schellmann, Hossein Panjideh, Patricia Fasold, Diana Bachran, Christopher Bachran

J Immunother· September 2012

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Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development.
Shihui Liu, Christopher Bachran, Pradeep Gupta, Sharmina Miller-Randolph, Hailun Wang

Proc Natl Acad Sci U S A· August 2012

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The toxin component of targeted anti-tumor toxins determines their efficacy increase by saponins.
Alexander Weng, Mayank Thakur, Figen Beceren-Braun, Diana Bachran, Christopher Bachran

Mol Oncol· June 2012

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The endocytic uptake pathways of targeted toxins are influenced by synergistically acting Gypsophila saponins.
Diana Bachran, Stefanie Schneider, Christopher Bachran, Alexander Weng, Matthias F Melzig

Mol Pharm· December 2011

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A lysine-free mutant of epidermal growth factor as targeting moiety of a targeted toxin.
Christopher Bachran, Stefanie Schneider, Sebastian B Riese, Diana Bachran, Romy Urban

Life Sci· January 2011

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Epidermal growth factor receptor expression affects the efficacy of the combined application of saponin and a targeted toxin on human cervical carcinoma cells.
Diana Bachran, Stefanie Schneider, Christopher Bachran, Romy Urban, Alexander Weng

Int J Cancer· September 2010

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Creation and characterization of a xenograft model for human cervical cancer.
Corinna Hoffmann, Christopher Bachran, Jonas Stanke, Sefer Elezkurtaj, Andreas M Kaufmann

Gynecol Oncol· July 2010

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A convenient method for saponin isolation in tumour therapy.
Alexander Weng, Kristina Jenett-Siems, Peter Schmieder, Diana Bachran, Christopher Bachran

J Chromatogr B Analyt Technol Biomed Life Sci· March 2010

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Meeting report on the second targeted tumor therapies.
Christopher Bachran, Hendrik Fuchs

Mol Cancer Ther· January 2010

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A simple method for isolation of Gypsophila saponins for the combined application of targeted toxins and saponins in tumor therapy.
Alexander Weng, Diana Bachran, Cornelia Görick, Christopher Bachran, Hendrik Fuchs

Planta Med· October 2009

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Inhibition of tumor growth by targeted toxins in mice is dramatically improved by saponinum album in a synergistic way.
Christopher Bachran, Horst Dürkop, Mark Sutherland, Diana Bachran, Christian Müller

J Immunother· September 2009

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The Fabisch-Symposium 2009 on Targeted Tumor Therapies.
Christopher Bachran, Hendrik Fuchs

Curr Drug Targets· February 2009

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Saponins in tumor therapy.
Christopher Bachran, Silke Bachran, Mark Sutherland, Diana Bachran, Hendrik Fuchs

Mini Rev Med Chem· June 2008

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