Publications by authors named "Christopher D Brown"

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A deep dive into statistical modeling of RNA splicing QTLs reveals variants that explain neurodegenerative disease.
David Wang, Matthew R Gazzara, San Jewell, Benjamin D Wales-McGrath, Kevin Yang, Christopher D Brown

Am J Hum Genet· December 2025

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QRS morphology and electrical dyssynchrony in patients before and after cardiac resynchronization therapy and after device optimization.
Michelle M Harbin, Christopher D Brown, Kevin V Burns, Emanuel A Espinoza, Donald R Dengel

J Electrocardiol· September 2025

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Expanded Chromatin Accessibility Mapping Explains Genetic Variation Associated with Complex Traits in Liver.
Brandon M Wenz, Max F Dudek, Shweta Ramdas, Kate Townsend Creasy, Dong Xin, Christopher D Brown

medRxiv· September 2025

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Electrical dyssynchrony mapping and optimization of nonresponders in patients programmed with the adaptive cardiac resynchronization therapy algorithm.
Alan J Bank, Kevin V Burns, Christopher D Brown, Evan Walser-Kuntz, Madeline A Czeck

Heart Rhythm· July 2025

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Characterization of non-coding variants associated with transcription-factor binding through ATAC-seq-defined footprint QTLs in liver.
Max F Dudek, Brandon M Wenz, Christopher D Brown, Benjamin F Voight, Laura Almasy

Am J Hum Genet· June 2025

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Genotype inference from aggregated chromatin accessibility data reveals genetic regulatory mechanisms.
Brandon M Wenz, Yuan He, Nae-Chyun Chen, Joseph K Pickrell, Jeremiah H Li, Christopher D Brown

Genome Biol· March 2025

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Effectiveness of Platelet-Rich Plasma in Reducing Pain and Increasing Function After Acute Lateral Ankle Sprain: A Critically Appraised Topic.
Erin Frey, Christopher D Brown, Brady Tripp

J Sport Rehabil· September 2024

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A Deep Dive into Statistical Modeling of RNA Splicing QTLs Reveals New Variants that Explain Neurodegenerative Disease.
David Wang, Matthew R Gazzara, San Jewell, Benjamin Wales-McGrath, Christopher D Brown

bioRxiv· September 2024

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Genotype inference from aggregated chromatin accessibility data reveals genetic regulatory mechanisms.
Brandon M Wenz, Yuan He, Nae-Chyun Chen, Joseph K Pickrell, Jeremiah H Li, Christopher D Brown

bioRxiv· September 2024

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Characterization of non-coding variants associated with transcription factor binding through ATAC-seq-defined footprint QTLs in liver.
Max F Dudek, Brandon M Wenz, Christopher D Brown, Benjamin F Voight, Laura Almasy

bioRxiv· September 2024

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Variant-to-function mapping of late-onset Alzheimer's disease GWAS signals in human microglial cell models implicates at the locus.
Elizabeth A Burton, Mariana Argenziano, Kieona Cook, Molly Ridler, Sumei Lu, Christopher D Brown

bioRxiv· August 2024

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Total synthesis of dissectol A, using an enediolate-based Tsuji-Trost reaction.
Ruben L H Andringa, Nittert Marinus, Daan V Bunt, Elizabeth R Haiderer, Robert B Abramovitch, Christopher D Brown

Chem Sci· July 2024

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Determination of sensed and paced atrial-ventricular delay in cardiac resynchronization therapy.
Alan J Bank, Christopher D Brown, Kevin V Burns, Katie M Johnson

Pacing Clin Electrophysiol· April 2024

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Field-portable detection of fentanyl and its analogs: A review.
Richard A Crocombe, Greg Giuntini, David W Schiering, Luisa T M Profeta, Michael D Hargreaves, Christopher D Brown

J Forensic Sci· September 2023

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Genome-wide association studies and fine-mapping identify genomic loci for n-3 and n-6 polyunsaturated fatty acids in Hispanic American and African American cohorts.
Chaojie Yang, Jenna Veenstra, Traci M Bartz, Matthew C Pahl, Brian Hallmark, Christopher D Brown

Commun Biol· August 2023

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Evaluating the Contribution of Cell Type-Specific Alternative Splicing to Variation in Lipid Levels.
Katerina A B Gawronski, William P Bone, YoSon Park, Evanthia E Pashos, Brandon M Wenz, Christopher D Brown

Circ Genom Precis Med· June 2023

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids.
Sarah E Graham, Shoa L Clarke, Kuan-Han H Wu, Stavroula Kanoni, Greg J M Zajac, Michael R Brown, Morris Brown, Christopher D Brown

Nature· June 2023

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A Nucleophilic Activity-Based Probe Enables Profiling of PLP-Dependent Enzymes.
Scott I Brody, Joseph A Buonomo, Moyosore O Orimoloye, Ziyi Jia, Sachin Sharma, Christopher D Brown

Chembiochem· April 2023

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The genetic and evolutionary basis of gene expression variation in East Africans.
Derek E Kelly, Shweta Ramdas, Rong Ma, Renata A Rawlings-Goss, Gregory R Grant, Christopher D Brown

Genome Biol· February 2023

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Cardiac resynchronization therapy optimization in nonresponders and incomplete responders using electrical dyssynchrony mapping.
Christopher D Brown, Kevin V Burns, Michelle M Harbin, Emanuel A Espinosa, Matthew D Olson

Heart Rhythm· December 2022

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Electrical dyssynchrony mapping and cardiac resynchronization therapy.
Alan J Bank, Christopher D Brown, Kevin V Burns, Emanuel A Espinosa, Michelle M Harbin

J Electrocardiol· December 2022

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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Stavroula Kanoni, Sarah E Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Michael R Brown, Morris Brown, Christopher D Brown

Genome Biol· December 2022

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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Shweta Ramdas, Jonathan Judd, Sarah E Graham, Stavroula Kanoni, Yuxuan Wang, Michael R Brown, Morris Brown, Christopher D Brown

Am J Hum Genet· August 2022

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Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease.
Hongbo Liu, Tomohito Doke, Dong Guo, Xin Sheng, Ziyuan Ma, Christopher D Brown

Nat Genet· July 2022

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A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.
Marijana Vujkovic, Shweta Ramdas, Kim M Lorenz, Xiuqing Guo, Rebecca Darlay, Christopher D Brown

Nat Genet· June 2022

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