Publications by authors named "Christopher D Bruno"

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Physiologically-based pharmacokinetic model for predicting drug-drug interactions perpetrated by posaconazole in healthy subjects with normal weight and obesity: Concomitant use and washout.
Christopher D Bruno, Ahmed Elmokadem, David J Greenblatt, Christina R Chow

J Pharmacokinet Pharmacodyn· July 2025

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Incomplete Data and Potential Risks of Drugs in People with Obesity.
Caroline M Apovian, Christopher D Bruno, Theodore K Kyle, Christina R Chow, David J Greenblatt

Curr Obes Rep· December 2023

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Estimation of Absolute and Relative Body Fat Content Using Noninvasive Surrogates: Can DXA Be Bypassed?
David J Greenblatt, Christopher D Bruno, Jerold S Harmatz, Bess Dawson-Hughes, Qingchen Zhang

J Clin Pharmacol· November 2023

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Clinical Consequences of Altered Drug Disposition in Obesity: Call for Change.
Christopher D Bruno, David J Greenblatt, Jerold S Harmatz, Christina R Chow

J Clin Pharmacol· November 2023

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Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies.
Eli Hatchwell, Edward B Smith, Shapour Jalilzadeh, Christopher D Bruno, Yassine Taoufik, Bruno Stankoff

Front Neurol· December 2022

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Drug Disposition in Subjects With Obesity: The Research Work of Darrell R. Abernethy.
David J Greenblatt, Christopher D Bruno, Jerold S Harmatz, Qingchen Zhang, Christina R Chow

J Clin Pharmacol· November 2022

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Brexpiprazole Pharmacokinetics in CYP2D6 Poor Metabolizers: Using Physiologically Based Pharmacokinetic Modeling to Optimize Time to Effective Concentrations.
Ahmed Elmokadem, Christopher D Bruno, Conrad Housand, Eric Burroughs Jordie, Christina R Chow

J Clin Pharmacol· January 2022

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Impact of Obesity on Brexpiprazole Pharmacokinetics: Proposal for Improved Initiation of Treatment.
Christopher D Bruno, Ahmed Elmokadem, Conrad Housand, Eric Burroughs Jordie, Christina R Chow

J Clin Pharmacol· January 2022

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Effect of lipophilicity on drug distribution and elimination: Influence of obesity.
Christopher D Bruno, Jerold S Harmatz, Su X Duan, Qingchen Zhang, Christina R Chow

Br J Clin Pharmacol· August 2021

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HLA associations with infliximab-induced liver injury.
Christopher D Bruno, Brandon Fremd, Rachel J Church, Ann K Daly, Guruprasad P Aithal

Pharmacogenomics J· October 2020

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Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy.
Peggy S Eis, Christopher D Bruno, Todd A Richmond, Igor J Koralnik, Barbara A Hanson, Bruno Stankoff

Front Neurol· March 2020

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