Publications by authors named "Christopher D Chien"

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International consensus guidelines for the conduct and reporting of CAR T-cell clinical trials in AML.
Swati Naik, Richard Aplenc, Susanne H C Baumeister, Marco Becilli, Anand S Bhagwat, Christopher D Chien

Blood Adv· December 2025

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Manufacture of CD22 CAR T cells following positive versus negative selection results in distinct cytokine secretion profiles and γδ T cell output.
Hannah W Song, Mehdi Benzaoui, Alka Dwivedi, Sarah Underwood, Lipei Shao, Christopher D Chien

Mol Ther Methods Clin Dev· March 2024

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Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against - mutant acute myeloid leukemia and -rearranged acute lymphoblastic leukemia.
Lisa M Niswander, Zachary T Graff, Christopher D Chien, John A Chukinas, Christina A Meadows

Haematologica· February 2023

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CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR.
Haneen Shalabi, Haiying Qin, Angela Su, Bonnie Yates, Pamela L Wolters, Christopher D Chien

Blood· August 2022

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Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design.
Haiying Qin, Lila Yang, John A Chukinas, Nirali Shah, Samiksha Tarun, Christopher D Chien

J Immunother Cancer· September 2021

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Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients.
Kazusa Ishii, Marie Pouzolles, Christopher D Chien, Rebecca A Erwin-Cohen, M Eric Kohler

J Clin Invest· October 2020

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TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance.
Yinmeng Yang, M Eric Kohler, Christopher D Chien, Christopher T Sauter, Elad Jacoby

Sci Transl Med· November 2017

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The functional interplay between systemic cancer and the hematopoietic stem cell niche.
Amber J Giles, Christopher D Chien, Caitlin M Reid, Terry J Fry, Deric M Park

Pharmacol Ther· December 2016

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CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Elad Jacoby, Sang M Nguyen, Thomas J Fountaine, Kathryn Welp, Berkley Gryder, Christopher D Chien

Nat Commun· July 2016

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Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD.
Elad Jacoby, Yinmeng Yang, Haiying Qin, Christopher D Chien, James N Kochenderfer

Blood· March 2016

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Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD.
Christian M Capitini, Nicole M Nasholm, Christopher D Chien, Shannon M Larabee, Haiying Qin

Blood· September 2014

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Regulation of HER2 oncogene transcription by a multifunctional coactivator/corepressor complex.
Jason P Garee, Christopher D Chien, Jordan V Li, Anton Wellstein, Anna T Riegel

Mol Endocrinol· June 2014

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Murine models of acute leukemia: important tools in current pediatric leukemia research.
Elad Jacoby, Christopher D Chien, Terry J Fry

Front Oncol· June 2014

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Transcriptional repression of AIB1 by FoxG1 leads to apoptosis in breast cancer cells.
Jordan V Li, Christopher D Chien, Jason P Garee, Jianming Xu, Anton Wellstein

Mol Endocrinol· July 2013

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An acetylation switch regulates SUMO-dependent protein interaction networks.
Rebecca Ullmann, Christopher D Chien, Maria Laura Avantaggiati, Stefan Muller

Mol Cell· June 2012

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Role of the nuclear receptor coactivator AIB1-Delta4 splice variant in the control of gene transcription.
Christopher D Chien, Alexander Kirilyuk, Jordan V Li, Wentao Zhang, Tyler Lahusen

J Biol Chem· July 2011

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Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.
Annabell S Oh, John T Lahusen, Christopher D Chien, Mark P Fereshteh, Xiaolong Zhang

Mol Cell Biol· November 2008

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Maximizing CD8+ T cell responses elicited by peptide vaccines containing CpG oligodeoxynucleotides.
James N Kochenderfer, Christopher D Chien, Jessica L Simpson, Ronald E Gress

Clin Immunol· August 2007

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Vaccination regimens incorporating CpG-containing oligodeoxynucleotides and IL-2 generate antigen-specific antitumor immunity from T-cell populations undergoing homeostatic peripheral expansion after BMT.
James N Kochenderfer, Jessica L Simpson, Christopher D Chien, Ronald E Gress

Blood· July 2007

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Synergism between CpG-containing oligodeoxynucleotides and IL-2 causes dramatic enhancement of vaccine-elicited CD8+ T cell responses.
James N Kochenderfer, Christopher D Chien, Jessica L Simpson, Ronald E Gress

J Immunol· December 2006

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Platelet FcgammaRIIA binds and internalizes IgG-containing complexes.
Randall G Worth, Christopher D Chien, Paul Chien, Michael P Reilly, Steven E McKenzie

Exp Hematol· November 2006

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In vivo magnetic resonance volumetric and spectroscopic analysis of mouse prostate cancer models.
Stanley T Fricke, Olga Rodriguez, John Vanmeter, Luis E Dettin, Mathew Casimiro, Christopher D Chien

Prostate· May 2006

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