Publications by authors named "Christopher D Scharer"

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Human lung CD8 tissue-resident memory T cell-derived interferon-γ orchestrates subset-specific antiviral programming in airway epithelial cells.
Cameron L R Mattingly, Ariana R Jimenez, M Elliott Williams, Kirsten N Kost, Laurel A Lawrence, Christopher D Scharer

Immunity· December 2025

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Homotypic endoplasmic reticulum membrane tethering is critical for flavivirus replication.
Jonathan Einterz Owen, Cheyanne Lee Bemis, Qingyi Wang, Ambarish C Varadan, Jacob W Vander Velden, Christopher D Scharer

bioRxiv· November 2025

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Single-Cell Transcriptomics Reveals Depletion and Dysregulation of Mycobacterium tuberculosis-Specific Th1 and Th17 Cells Early After Acquisition of Human Immunodeficiency Virus.
Rachel A Pearson, Krista N Krish, Wendy E Whatney, Walter Jaoko, Kishor Mandaliya, Christopher D Scharer

J Infect Dis· October 2025

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G9a controls plasma cell differentiation through FOXO1 and ETS1 binding site regulatory networks.
Lou-Ella M M George-Alexander, Roshni Roy, Anna K Kania, Sakeenah L Hicks, Mansi Gupta, Christopher D Scharer

J Immunol· September 2025

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CXCR5 Signals Fine-Tune Dendritic Cell Transcription and Regulate T2 Development.
Miranda L Curtiss, Natalia Ballesteros Benavides, Alexander F Rosenberg, Christopher D Scharer, Beatriz León

Vaccines (Basel)· September 2025

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Transcription factor T-bet regulates the maintenance and differentiation potential of lymph node and lung effector memory B cell subsets.
Christopher A Risley, Michael D Schultz, S Rameeza Allie, Shanrun Liu, Jessica N Peel, Christopher D Scharer

Immunity· July 2025

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The Microbial Metabolite δ-Valerobetaine Strengthens the Gut Epithelial Barrier.
Lauren C Askew, C Anthony Gacasan, Maria E Barbian, Jaclyn Weinberg, Liping Luo, Christopher D Scharer

Am J Pathol· June 2025

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Murine modeling of menstruation identifies immune correlates of protection during Chlamydia muridarum challenge.
Laurel A Lawrence, Mark Elliott Williams, Paola Vidal, Richa S Varughese, Zheng-Rong Tiger Li, Christopher D Scharer

PLoS Pathog· June 2025

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EZH2 coordinates memory B-cell programming and recall responses.
Keenan J Wiggins, Mark E Williams, Sakeenah L Hicks, Herbey O Padilla-Quirarte, Jobaida Akther, Christopher D Scharer

J Immunol· May 2025

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An early precursor CD8 T cell that adapts to acute or chronic viral infection.
Daniel T McManus, Rajesh M Valanparambil, Christopher B Medina, Christopher D Scharer, Donald J McGuire

Nature· April 2025

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Fgl2 regulates FcγRIIB+CD8+ T cell responses during infection.
Anna B Morris, Max W Adelman, Kelsey B Bennion, Catherine D Martinez, Kem-Maria McCook, Christopher D Scharer

JCI Insight· April 2025

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MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulation.
Elizabeth M Kline, Janna E Jernigan, Christopher D Scharer, Jeffrey Maurer, Sakeenah L Hicks

Sci Rep· April 2025

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MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulation.
Elizabeth M Kline, Janna E Jernigan, Christopher D Scharer, Jeffrey Maurer, Sakeenah Hicks Sl

bioRxiv· March 2025

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Human immune organoids to decode B cell response in healthy donors and patients with lymphoma.
Zhe Zhong, Manuel Quiñones-Pérez, Zhonghao Dai, Valeria M Juarez, Eshant Bhatia, Christopher D Scharer

Nat Mater· February 2025

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Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Caterina E Faliti, Trinh T P Van, Fabliha A Anam, Narayanaiah Cheedarla, M Elliott Williams, Christopher D Scharer

Nat Immunol· January 2025

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Publisher Correction: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Caterina E Faliti, Trinh T P Van, Fabliha A Anam, Narayanaiah Cheedarla, M Elliott Williams, Christopher D Scharer

Nat Immunol· January 2025

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Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis.
Cody Elkins, Chengyu Ye, Pulavendran Sivasami, Roy Mulpur, Pamela P Diaz-Saldana, Christopher D Scharer

Sci Immunol· January 2025

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Nr4a1 and Nr4a3 redundantly control clonal deletion and contribute to an anergy-like transcriptome in auto-reactive thymocytes to impose tolerance in mice.
Hailyn V Nielsen, Letitia Yang, James L Mueller, Alexander J Ritter, Ryosuke Hiwa, Christopher D Scharer

Nat Commun· January 2025

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Xist RNA Dependent and Independent Mechanisms Regulate Dynamic X Chromosome Inactivation in B Lymphocytes.
Natalie E Toothacre, Kiara L Rodríguez-Acevedo, Keenan J Wiggins, Christopher D Scharer, Montserrat C Anguera

bioRxiv· January 2025

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Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4CD8αα intraepithelial T cells.
Naomi Rodriguez-Marino, Charlotte J Royer, Dormarie E Rivera-Rodriguez, Emma Seto, Isabelle Gracien, Christopher D Scharer

Mucosal Immunol· December 2024

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Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis.
Caterina E Faliti, Maria Mesina, Jinyong Choi, Simon Bélanger, Monique A Marshall, Christopher D Scharer

Immunity· December 2024

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Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control.
Sarah A Weiss, Amy Y Huang, Megan E Fung, Daniela Martinez, Alex C Y Chen, Christopher D Scharer

Nat Immunol· October 2024

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Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine.
Selene Meza-Perez, Mingyong Liu, Aaron Silva-Sanchez, Casey D Morrow, Peter G Eipers, Christopher D Scharer

Cell Host Microbe· July 2024

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Measuring B Cell Chromatin Accessibility by One-Step ATAC-seq.
Sakeenah L Hicks, Christopher D Scharer

Methods Mol Biol· July 2024

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Epigenomic Profiling of B Cell Subsets by CUT&Tag.
Bagdeser Akdogan-Ozdilek, Lou-Ella M M George-Alexander, Christopher D Scharer

Methods Mol Biol· July 2024

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