Publications by authors named "Christopher D Wiley"

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Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.
Azar Asadi Shahmirzadi, Daniel Edgar, Chen-Yu Liao, Yueh-Mei Hsu, Mark Lucanic, Arash Asadi Shahmirzadi, Christopher D Wiley, Garbo Gan, Dong Eun Kim, Herbert G Kasler

Cell Metab· September 2020

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Propagation of senescent phenotypes by extracellular HMGB1 is dependent on its redox state.
Ji-Won Shin, Dong-Hyun Jang, So Young Kim, Je-Jung Lee, Tae-Hwan Gil, Christopher D Wiley

Metabolism· July 2025

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Mitochondria-Targeted Catalase Does Not Suppress Development of Cellular Senescence during Aging.
Bronwyn A Mogck, Samantha T Jezak, Christopher D Wiley

Biomedicines· February 2024

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Senescent cells at the crossroads of aging, disease, and tissue homeostasis.
Chisaka Kuehnemann, Christopher D Wiley

Aging Cell· January 2024

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Rate-Limiting Enzymes in Cardiometabolic Health and Aging in Humans.
Laurence D Parnell, Kira S McCaffrey, Athena W Brooks, Caren E Smith, Chao-Qiang Lai, Christopher D Wiley

Lifestyle Genom· December 2023

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Characterization of novel mouse models to study the role of necroptosis in aging and age-related diseases.
Ramasamy Selvarani, Hoang Van Michelle Nguyen, Nidheesh Thadathil, Roman F Wolf, Willard M Freeman, Christopher D Wiley

Geroscience· December 2023

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Chow diet in mouse aging studies: nothing regular about it.
Jennifer Lee, Chloe Purello, Sarah L Booth, Brian Bennett, Christopher D Wiley

Geroscience· June 2023

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Cholesterol drives inflammatory senescence.
Chisaka Kuehnemann, Christopher D Wiley

Nat Metab· March 2023

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Cellular Senescence, a Novel Area of Investigation for Metastatic Diseases.
Francesca Faggioli, Michael C Velarde, Christopher D Wiley

Cells· March 2023

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Antiretroviral protease inhibitors induce features of cellular senescence that are reversible upon drug removal.
Chisaka Kuehnemann, Jun-Wei B Hughes, Pierre-Yves Desprez, Simon Melov, Christopher D Wiley

Aging Cell· January 2023

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Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype.
Chisaka Kuehnemann, Kang-Quan Hu, Kayla Butera, Sandip K Patel, Joanna Bons, Christopher D Wiley

Front Endocrinol (Lausanne)· August 2022

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The metabolic roots of senescence: mechanisms and opportunities for intervention.
Christopher D Wiley, Judith Campisi

Nat Metab· October 2021

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Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis.
Christopher D Wiley, Rishi Sharma, Sonnet S Davis, Jose Alberto Lopez-Dominguez, Kylie P Mitchell, Samantha Wiley

Cell Metab· June 2021

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Author Correction: Senescent cells promote tissue NAD decline during ageing via the activation of CD38 macrophages.
Anthony J Covarrubias, Abhijit Kale, Rosalba Perrone, Jose Alberto Lopez-Dominguez, Angela Oliveira Pisco, Christopher D Wiley

Nat Metab· January 2021

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Senescent cells promote tissue NAD decline during ageing via the activation of CD38 macrophages.
Anthony J Covarrubias, Abhijit Kale, Rosalba Perrone, Jose Alberto Lopez-Dominguez, Angela Oliveira Pisco, Christopher D Wiley

Nat Metab· November 2020

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Cellular Senescence Promotes Skin Carcinogenesis through p38MAPK and p44/42MAPK Signaling.
Fatouma Alimirah, Tanya Pulido, Alexis Valdovinos, Sena Alptekin, Emily Chang, Christopher D Wiley

Cancer Res· September 2020

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Bubble Bubble, Senescent Cells Are a Cauldron of Tumor Trouble.
Christopher D Wiley

Cancer Res· August 2020

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Role of Senescent Renal Cells in Pathophysiology of Diabetic Kidney Disease.
Christopher D Wiley

Curr Diab Rep· June 2020

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Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin.
Dong Eun Kim, Martijn E T Dollé, Wilbert P Vermeij, Akos Gyenis, Katharina Vogel, Christopher D Wiley

Aging Cell· March 2020

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Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis.
Christopher D Wiley, Alexis N Brumwell, Sonnet S Davis, Julia R Jackson, Alexis Valdovinos

JCI Insight· December 2019

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SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells.
Christopher D Wiley, Su Liu, Chandani Limbad, Anna M Zawadzka, Jennifer Beck

Cell Rep· September 2019

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Measurement of Metabolite Changes in Senescent Cells by Mass Spectrometry.
Christopher D Wiley, Sonnet Davis, Arvind Ramanathan

Methods Mol Biol· August 2019

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Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype.
Christopher D Wiley, Nicholas Schaum, Fatouma Alimirah, Jose Alberto Lopez-Dominguez, Arturo V Orjalo

Sci Rep· February 2018

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Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence.
Christopher D Wiley, James M Flynn, Christapher Morrissey, Ronald Lebofsky, Joe Shuga

Aging Cell· October 2017

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Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells.
Kevin M Perrott, Christopher D Wiley, Pierre-Yves Desprez, Judith Campisi

Geroscience· April 2017

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