Cell Metab September 2020 PMID 32877690

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.

Azar Asadi Shahmirzadi, Daniel Edgar, Chen-Yu Liao, Yueh-Mei Hsu, Mark Lucanic, Arash Asadi Shahmirzadi, Christopher D Wiley, Garbo Gan, Dong Eun Kim, Herbert G Kasler, Chisaka Kuehnemann, Brian Kaplowitz, Dipa Bhaumik, Rebeccah R Riley, Brian K Kennedy

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Mentions

192

Peak: 79 in Sep 2020

across 5 sources since Sep 2020

Extended reach

695,331

potential audience

Total likes

3,884

Video views

144,449

Mentions per month

Sep 2020 – Aug 2025

Where it's discussed

X / Twitter140 posts
News39 articles
Blogs6 articles
Reddit4 posts
YouTube3 videos

AI synopsis

What people are saying

Numerous discussions highlight the benefits of AKG, with posts mentioning its role in reducing chronic inflammation and its promising effects on lifespan in mice. Phrases like 'healthspan extender' and references to personal programs integrating AKG supplements underscore the overall excitement and potential applications of the findings, suggesting a positive tone toward the research.

AgreementStrong agreement

Most posts reflect strong support for the research findings about alpha-ketoglutarate (AKG) extending lifespan.

InterestHigh interest

The discussion shows a high level of interest, with many contributors referencing the study and expressing curiosity about its implications.

EngagementModerate engagement

While there are thoughtful exchanges about the research, many posts are largely promotional or reiterative without deep analysis.

ImpactHigh impact

Participants perceive the research as having significant potential implications for healthspan and longevity.

Abstract in brief

Alpha-ketoglutarate (CaAKG), a metabolite involved in the TCA cycle, was studied for its impact on healthspan and lifespan in aging mice.
The research revealed that CaAKG leads to a longer, healthier life by lowering inflammatory cytokines, particularly through the induction of IL-10 which helps to mitigate chronic inflammation.
In this mouse model, CaAKG not only reduces frailty but also compresses morbidity, meaning it extends lifespan while improving overall health during aging.

Read the full abstract

All mentions

Impact of Alpha-Ketoglutarate on Healthspan and Aging Biomarkers

In this video, I speak with Prof Brian Kennedy about his research at The Centre for Healthy Aging. We explore how alpha-ketoglutarate influences human aging, its role in clinical trials, and its potential to extend…

The Sheekey Science Show · May 14, 2021 73,187 views

CaAKG: Enhancing Lifespan and Healthspan in Aging Mice

Alpha-ketoglutarate (CaAKG) is a crucial metabolite in the TCA cycle. It has been shown to extend healthspan and lifespan in aging mice by reducing inflammation and frailty. This video delves into the significant…

The Sheekey Science Show · Sep 1, 2020 70,943 views

Impact of Calcium AKG on Longevity and Healthspan

Discover the power of Calcium AKG (CaAKG) and its transformative impact on longevity and lifespan. Research shows CaAKG reduces inflammation and improves health during aging. Watch now to explore the science behind this…

Outlive · Jan 24, 2025 320 views

Mike Muldoon

@doonerjax · X

@davidasinclair Rejuvant!! Azar Asadi Shahmirzadi, et al. “Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice.” doi: https://t.co/WFbuKEV2aK. https://t.co/Notnmpe4He

Aug 30, 2025 · 1 like · 304 followers View post →

Mike Muldoon

@doonerjax · X

@biluhuang @greek_scientist @bryan_johnson Azar Asadi Shahmirzadi, et al. “Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice.” doi: https://t.co/WFbuKEV2aK. https://t.co/Notnmpe4He

Aug 13, 2025 · 304 followers View post →

Madam Mitochondria

@Madam_Mito · X

May 25, 2024 · 6 likes · 10,521 followers View post →

Bioecomatics

@bioecomatic · X

RT @agingdoc1: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020) https://t.co/…

Apr 26, 2024 · 7 shares · 106 followers View post →

Bayar Jaff

@JaffBayar · X

RT @agingdoc1: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020) https://t.co/…

Apr 26, 2024 · 7 shares · 605 followers View post →

AngryPhDstudent❗️❗️❗️

@ONNESHA092 · X

RT @agingdoc1: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020) https://t.co/…

Apr 26, 2024 · 7 shares · 184 followers View post →

Mind Your Science!

@MindYourSci · X

RT @agingdoc1: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020) https://t.co/…

Apr 26, 2024 · 7 shares · 132 followers View post →

Science

@Long_life_sci · X

RT @agingdoc1: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020) https://t.co/…

Apr 25, 2024 · 7 shares · 33 followers View post →

Dr L Boominathan PhD

@DrLBoominathan · X

RT @agingdoc1: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020) https://t.co/…

Apr 25, 2024 · 7 shares · 879 followers View post →

Dieter

@Wuhle · X

RT @agingdoc1: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020) https://t.co/…

Apr 25, 2024 · 7 shares · 490 followers View post →

Agingdoc

@agingdoc1 · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020) https://t.co/ejVuam3chc | @Cell_Metabolism https://t.co/bRzXUwUdDF

Apr 25, 2024 · 25 likes · 7 shares · 41,671 followers View post →

キムチ牛どん

@kimuchi04 · X

RT @okamura_yt: https://t.co/9dmLBf73Vu αケトグルタル酸（AKG）はTCA回路を構成する代謝物の一つ。線虫やハエで寿命延長効果が認められている。高齢マウスのエサに入れて投与したところ、寿命、健康寿命が延長した。AKG投与で慢性炎症の抑制…

Oct 22, 2023 · 1 share · 705 followers View post →

岡村勇輝　Yuki T. Okamura

@okamura_yt · X

https://t.co/9dmLBf73Vu αケトグルタル酸（AKG）はTCA回路を構成する代謝物の一つ。線虫やハエで寿命延長効果が認められている。高齢マウスのエサに入れて投与したところ、寿命、健康寿命が延長した。AKG投与で慢性炎症の抑制、in vitroでSASPの抑制も観察されている。Cell Metabolism, 2020.

Oct 21, 2023 · 1 like · 1 share · 7 followers View post →

Dave's not here, Man

@davidfamlawyer · X

@Oleander209 Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/GWL26PJXbF

Oct 21, 2023 · 1,513 followers View post →

Julie Parker

@JulieParker144 · X

CaAKG - the healthspan extender you need to know about? https://t.co/s82ByTiYAC via @YouTube https://t.co/9yj1PaedBd

Aug 20, 2023 · 25,905 followers View post →

MamaMcBear

@mamamcbear1 · X

CaAKG - the healthspan extender you need to know about? https://t.co/l2D3dGpSv5 via @YouTube

Aug 19, 2023 · 2,362 followers View post →

AMERICA'S BEST PATRIOT☄️

@AlisonBoxxer · X

https://t.co/AjYSH7ULRk

Jul 8, 2023 · 9,656 followers View post →

Advanced Health Center | Integrative Medicine

@advhealthctr · X

Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice https://t.co/d6oO9Lap1u Advanced Health Center | Integrative & Functional Medicine. @advhealthctr @louis_lziegler3 #DMV #arlingtonva #alexandriava #Nutrition

May 26, 2023 · 319 followers View post →

Marx

@Marx04882911 · X

RT @Marx04882911: ผู้ผลิตชีวภาพสูงวัยและ #ความคาดหวังในอนาคตสำหรับการขยายอายุขัย ของมนุษย์ https://t.co/2DFD8OKCkl

Mar 28, 2023 · 1 share · 981 followers View post →

Marx

@Marx04882911 · X

ผู้ผลิตชีวภาพสูงวัยและ #ความคาดหวังในอนาคตสำหรับการขยายอายุขัย ของมนุษย์ https://t.co/2DFD8OKCkl

Mar 28, 2023 · 1 share · 981 followers View post →

Longevity

@LongevityTao · X

Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice https://t.co/L5hoOVu6zr

Mar 11, 2023 · 332 followers View post →

C.T. Freeman

@c_t_freeman · X

Extending healthspan: AKG, human clinical trials & aging biomarkers (Pro... https://t.co/kiXWREcYk6 via @YouTube

Mar 8, 2023 · 383 followers View post →

Sharah Mae Capinpin

@Capinpin_S · X

RT @HealthyLongeviT: First off on our series of #AgeingHighlights, we have a 2020 paper from @BKennedy_aging on how AKG supplementation ext…

May 24, 2022 · 1 share · 102 followers View post →

Centre for Healthy Longevity

@LongevitySG · X

First off on our series of #AgeingHighlights, we have a 2020 paper from @BKennedy_aging on how AKG supplementation extended healthspan and lifespan in mice. Read all about it here: https://t.co/DB4RTgurbq

May 24, 2022 · 3 likes · 1 share · 2,479 followers View post →

Orlando_uy

@Orlando_uy · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. https://t.co/8jTA37IIBX

Apr 20, 2022 · 2 likes · 694 followers View post →

KELLY SULLIVAN

@KELLYGIRL9 · X

Extending healthspan: AKG, human clinical trials & aging biomarkers (Pro... https://t.co/APGZLIaPdq via @YouTube

Jan 17, 2022 · 584 followers View post →

İskender-i Zülkarneyn

@zuci313 · X

RT @EleanorSheekey: Second interview!! I recently had the pleasure to speak with Prof Brian Kennedy @NUSingapore about human aging clinical…

Dec 8, 2021 · 5 shares · 158 followers View post →

Liz Rose

@LizRose14449371 · X

https://t.co/2kzQYFOykS

Dec 1, 2021 · 1 like · 148 followers View post →

realneil

@realneil3 · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/6pmcAHN46o

Oct 31, 2021 · 676 followers View post →

TopologicApple

@topologic_apple · X

@runsalot48 @mkaeberlein They all have very strong data. https://t.co/D7LtaWV3XL https://t.co/MP8xP5cRFs https://t.co/FnUudT72qX

Oct 17, 2021 · 2,920 followers View post →

Rene Sugar

@renesugar · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/oHK8BtRvld https://t.co/aTTfS1l3BJ "AKG reduces chronic inflammation and induces IL-10 in T cells of female mice"

Sep 7, 2021 · 3,971 followers View post →

Eleanor Sheekey

@EleanorSheekey · X

RT @BKennedy_aging: Had fun talking with @EleanorSheekey about AKG, clinical trials and #biomarkers. https://t.co/rSmY2JTPkn

Jul 27, 2021 · 2 shares · 4,885 followers View post →

Diogo Barardo, Geroscientist

@BarardoD · X

RT @BKennedy_aging: Had fun talking with @EleanorSheekey about AKG, clinical trials and #biomarkers. https://t.co/rSmY2JTPkn

Jul 27, 2021 · 2 shares · 683 followers View post →

Brian Kennedy

@BKennedy_aging · X

Had fun talking with @EleanorSheekey about AKG, clinical trials and #biomarkers. https://t.co/rSmY2JTPkn

Jul 27, 2021 · 13 likes · 2 shares · 7,168 followers View post →

Ricky

@ricky89449195 · X

RT @1LEOOEL1: [

Jul 26, 2021 · 1 share · 310 followers View post →

QuantumAI+Crispr3D=QuInCy=QAI&C3D=LA

@1LEOOEL1 · X

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Jul 25, 2021 · 3 likes · 1 share · 2,940 followers View post →

Based Hatter

@BasedHatter · X

RT @EleanorSheekey: Second interview!! I recently had the pleasure to speak with Prof Brian Kennedy @NUSingapore about human aging clinical…

Jun 28, 2021 · 5 shares · 4,511 followers View post →

ScienceStop

@B0tSci · X

RT @EleanorSheekey: Second interview!! I recently had the pleasure to speak with Prof Brian Kennedy @NUSingapore about human aging clinical…

Jun 28, 2021 · 5 shares · 4,074 followers View post →

DomTheBoss

@uberrimaefidei1 · X

RT @EleanorSheekey: Second interview!! I recently had the pleasure to speak with Prof Brian Kennedy @NUSingapore about human aging clinical…

Jun 28, 2021 · 5 shares · 625 followers View post →

Tuyen Nguyen

@CodementorJS · X

RT @Rejuvant: Great interview from @EleanorSheekey with our Chief Science Officer, Dr. Brian Kennedy. Check her show out - The Sheekey Sci…

May 22, 2021 · 4 shares · 366 followers View post →

Eve.S.

@yeeseak · X

RT @Rejuvant: Great interview from @EleanorSheekey with our Chief Science Officer, Dr. Brian Kennedy. Check her show out - The Sheekey Sci…

May 15, 2021 · 4 shares · 875 followers View post →

Agingdoc

@agingdoc1 · X

@EleanorSheekey + @BKennedy_aging ( & neither are cartoons) = https://t.co/eAQZSYm479 A New Sheeky Science Show format @LongevityTech @TheAgingField @longevityleader @BuckInstitute

May 14, 2021 · 1 like · 41,621 followers View post →

Bill Walker

@BWalkerTTAGGG · X

RT @Rejuvant: Great interview from @EleanorSheekey with our Chief Science Officer, Dr. Brian Kennedy. Check her show out - The Sheekey Sci…

May 14, 2021 · 4 shares · 1,376 followers View post →

Eleanor Sheekey

@EleanorSheekey · X

RT @Rejuvant: Great interview from @EleanorSheekey with our Chief Science Officer, Dr. Brian Kennedy. Check her show out - The Sheekey Sci…

May 14, 2021 · 4 shares · 4,885 followers View post →

The Science to Resist Aging

@Rejuvant · X

Great interview from @EleanorSheekey with our Chief Science Officer, Dr. Brian Kennedy. Check her show out - The Sheekey Science Show with great interviews and explainer videos! https://t.co/xFDlR8jfPt

May 14, 2021 · 6 likes · 4 shares · 235 followers View post →

Academic YouTubers

@YTacademics · X

RT @EleanorSheekey: Second interview!! I recently had the pleasure to speak with Prof Brian Kennedy @NUSingapore about human aging clinical…

May 14, 2021 · 5 shares · 2,106 followers View post →

Eleanor Sheekey

@EleanorSheekey · X

May 14, 2021 · 27 likes · 5 shares · 4,885 followers View post →

OpenSci Talk

@OpenSciTalk · X

RT @RobotRrid: RRIDs were included in the Cell Metabolism paper "Alpha-Ketoglutarate, an Endogenous Metabolite, Ext…" (https://t.co/fVrHxRW…

Apr 30, 2021 · 1 share · 4,089 followers View post →

RRID Robot

@RobotRrid · X

RRIDs were included in the Cell Metabolism paper "Alpha-Ketoglutarate, an Endogenous Metabolite, Ext…" (https://t.co/fVrHxRWOKQ). RRIDs like this improve reproducibility in scientific research. #STMpublishing #OpenScience

Apr 30, 2021 · 1 share · 161 followers View post →

Agingdoc

@agingdoc1 · X

RT @agingdoc1: @FinnemoreRobb @BKennedy_aging Hi Robb, yes I periodically cover @BKennedy_aging's w/ you @ PDLH & via @NUSingapore/@BuckIns…

Jan 15, 2021 · 1 share · 41,621 followers View post →

Agingdoc

@agingdoc1 · X

@FinnemoreRobb @BKennedy_aging @NUSingapore @BuckInstitute @EleanorSheekey For those not aware of the work, refer to https://t.co/wt2Dzhunk6 which Brian discussed at ARDD [hosted @biogerontology]: https://t.co/wgXGzoOx8I . As Background, the @Rejuvant LifeTabs caAKG @ PDLH PR (other in develop.): https://t.co/6LPX2K75Lw. (Robb is CFO) -@agingdoc1

Jan 15, 2021 · 1 like · 41,671 followers View post →

Agingdoc

@agingdoc1 · X

@FinnemoreRobb @BKennedy_aging Hi Robb, yes I periodically cover @BKennedy_aging's w/ you @ PDLH & via @NUSingapore/@BuckInstitute (https://t.co/YItoOxgLMP & more recently link➡️@EleanorSheekey's vid https://t.co/83r6O2E2xv). Quality AKG work: Refreshing to see a supplement comp. work w/

Jan 15, 2021 · 2 likes · 1 share · 41,621 followers View post →

Albert J. Sarmentero.

@AlSarmentero · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/5oV5SivIs2

Dec 16, 2020 · 614 followers View post →

Saskia

@Saskia51012764 · X

CaAKG - the healthspan extender you need to know about? https://t.co/kcAshqsbB1 via @YouTube

Dec 5, 2020 · 315 followers View post →

Rapamycin News

@RapaNews · X

@drbstanfield Do you have any idea why Brian Kennedy/Buck Inst. chose the Calcium version of AKG in their study (over the many other versions of AKG)? https://t.co/fFeWPxMDUY

Nov 13, 2020 · 5,312 followers View post →

Rapamycin News

@RapaNews · X

@Orlando_uy Do you have any idea why they chose the Ca-AKG variant for the Buck Institute study? https://t.co/fFeWPxMDUY

Nov 13, 2020 · 1 like · 5,312 followers View post →

Agingdoc

@agingdoc1 · X

@nick_krontiris @BKennedy_aging @Rejuvant @BuckInstitute @NUSingapore ...work is solid though many details of translation remain to be worked out ( which population/setting, etc). See @BKennedy_aging & Gordon Lithgow’s @BuckInstitute collaboration https://t.co/vbxEbyAA9o & his #ardd2020 talk https://t.co/wgXGzoOx8I . Likely ⬆️RBC glutathione also.

Oct 31, 2020 · 41,671 followers View post →

Rene Sugar

@renesugar · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Oct 28, 2020 · 41 shares · 3,971 followers View post →

Rene Sugar

@renesugar · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Oct 23, 2020 · 41 shares · 3,971 followers View post →

Ciência Pra Você - UFMG

@cienciapravoce · X

Lembrem-se: essa suplementação deve ser feita com acompanhamento de médico ou de um nutricionista!! O consumo desse suplemento pode trazer efeitos adversos, como: levar a uma queda excessiva da pressão arterial, causar náuseas, vômitos e diarreias. Fonte: https://t.co/vdUqJivftH

Oct 23, 2020 · 200 followers View post →

Omid Mashinchian, PhD | BMeD

@OMID_MASH · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice: Cell Metabolism https://t.co/vnUxADFVtk

Oct 11, 2020 · 3 likes · 701 followers View post →

Goose

@virus_dog_lover · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice

Oct 10, 2020 · 105 followers View post →

Czech Centre for Phenogenomics

@CZphenogenomics · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 29, 2020 · 41 shares · 657 followers View post →

りっくる

@rikkururikkuru · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 27, 2020 · 41 shares · 1 followers View post →

Viviana

@VivianAya93 · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 22, 2020 · 41 shares · 134 followers View post →

john morley

@drjohnmorley · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/ZXehJyGUDM

Sep 21, 2020 · 1 like · 8,319 followers View post →

Claudio de Lucia, M.D., Ph.D.

@cladelucia · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 1,757 followers View post →

Lagarde Damien

@DamienLagarde · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 83 followers View post →

Hamidullah Khan, PhD

@IamKhanPhD · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 1,863 followers View post →

@DomenicoSergi

@Domenico_Sergi9 · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 218 followers View post →

Vern Dolinsky

@VernDolinsky · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 857 followers View post →

Celia P. Martinez-Jimenez

@celia4science · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 395 followers View post →

SNZK

@shinopp · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 723 followers View post →

Chris B

@Chris_theAI_Guy · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 465 followers View post →

Philippe Froguel

@philippefroguel · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 5,024 followers View post →

Dieter

@Wuhle · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 490 followers View post →

Shubhrajyoti Das (Nontu)

@ShubhraJ_Das · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 255 followers View post →

Aguilar-Arnal lab

@lwrena · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 568 followers View post →

Gilles Gouspillou

@GGouspillou · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 21, 2020 · 41 shares · 1,824 followers View post →

Danielle Hammond, MD

@DanielleHammo20 · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 2,689 followers View post →

Dr. Helen E. Collins

@DrHelenECollin1 · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 2,203 followers View post →

Lum Lab

@lum_lab · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 1,205 followers View post →

Luis Saraiva

@saraivalmr · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 1,121 followers View post →

Maribel Hernandez Alvarez

@Maribel_h_a · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 272 followers View post →

Hugo Angulo

@thermotronica · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 2,990 followers View post →

Coralie Sengenès

@CoraSen · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 103 followers View post →

Jim Johnson, PhD

@JimJohnsonSci · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 12,811 followers View post →

Andrés Caicedo Lab

@CaicedoLab · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 1,651 followers View post →

Spencer Haws

@SpencerHaws · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 194 followers View post →

JV Cabral-Costa

@jvccosta · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 870 followers View post →

P Kritsiligkou

@Parikki · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 763 followers View post →

Keto Brainz Nootropics

@ketobrainz · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 1,733 followers View post →

marcelo flores opazo

@flowersmarcelo · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 185 followers View post →

Rig-like receptor

@pakoTriana · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 165 followers View post →

Ron June

@ronjune2 · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 1,056 followers View post →

Pavithra Viswanath

@Dr_PViswanath · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 502 followers View post →

João Albuquerque

@Albuquerquejp85 · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 235 followers View post →

Geoffroy Mallaret

@MallaretG · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 623 followers View post →

Eduardo Silva-Pavez

@EduSilvaPavez · X

RT @Cell_Metabolism: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qD…

Sep 20, 2020 · 41 shares · 134 followers View post →

Cell Metabolism

@Cell_Metabolism · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/qDk8XsDioh

Sep 20, 2020 · 143 likes · 41 shares · 53,854 followers View post →

DesignedByNature

@DesignedNature · X

I just posted "Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice - Sep 2020" on Reddit https://t.co/ydMsPqOf3Z

Sep 8, 2020 · 439 followers View post →

AntonioM

@saludatm · X

ALFA-CETOGLUTARATO y aumento de la esperanza de vida. (Ratones). https://t.co/6HO3L8Cj3R

Sep 7, 2020 · 382 followers View post →

the paper link

@the_paper_link · X

RT @the_paper_link: Trend up+12: **Asadi Shahmirzadi A** et al (Cell Metab) __Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifesp…

Sep 5, 2020 · 1 share · 136 followers View post →

devrim öz arslan

@ozarsland · X

RT @FrezzaLab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/Bt1jE2Vs…

Sep 4, 2020 · 18 shares · 98 followers View post →

Bruno Ramos-Molina, PhD

@Brunorm84 · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice @Cell_Metabolism https://t.co/sGsP4oJi0y

Sep 4, 2020 · 3 likes · 6,443 followers View post →

Rahm Ramanathan MD, PhD

@Rahm_Ramanathan · X

Nice study on AKG metabolite supplementation to ameliorate aging in mouse models. Looking forward to results from the ongoing human trial https://t.co/sPSq2MC94q

Sep 4, 2020 · 1 like · 198 followers View post →

the paper link

@the_paper_link · X

Trend up+12: **Asadi Shahmirzadi A** et al (Cell Metab) __Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice__ https://t.co/3xAuPEf1DH

Sep 4, 2020 · 1 share · 136 followers View post →

UpToPhate

@UpToPhate · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. https://t.co/jIX4QWWDs1

Sep 3, 2020 · 196 followers View post →

Juhana Harju

@JuhanaHarju · X

RT @manish_chamoli: Checkout this fantastic work from our lab @Cell_Metabolism by Asadi Shahmirzadi et al. showing Alpha-Ketoglutarate, an…

Sep 3, 2020 · 1 share · 1,691 followers View post →

M3 - Molecular Metabolism and Metabolomics

@M3_Faergeman · X

RT @BartolomucciLab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/w…

Sep 3, 2020 · 1 share · 575 followers View post →

Alessandro Bartolomucci Lab

@BartolomucciLab · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/wLWLwHXv9c

Sep 3, 2020 · 2 likes · 1 share · 1,519 followers View post →

Joelle Allouche

@berjoalb · X

RT @MyAgeGroup: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in #Aging Mice L.P. https://t.co/…

Sep 3, 2020 · 4 shares · 257 followers View post →

Bérénice A. Benayoun, PhD

@BBParis1984 · X

RT @MyAgeGroup: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in #Aging Mice L.P. https://t.co/…

Sep 2, 2020 · 4 shares · 3,418 followers View post →

Ron June

@ronjune2 · X

RT @KFW_Lab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/YYrUNgrtJw

Sep 2, 2020 · 1 share · 1,056 followers View post →

Edward Anderton

@EdwardAnderton7 · X

RT @MyAgeGroup: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in #Aging Mice L.P. https://t.co/…

Sep 2, 2020 · 4 shares · 1,490 followers View post →

George Dawson

@dawso007 · X

"Mice given the substance—alpha-ketoglutarate (AKG)—were healthier as they aged, and females lived longer than mice not on the supplement." Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/iMfkDHd5Ws

Sep 2, 2020 · 6 likes · 7,806 followers View post →

Carbon Knowledge

@CarbonKnowledge · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/kjOkJ9v491

Sep 2, 2020 · 63 followers View post →

Ashish Kumar

@CddrAshu · X

RT @FrezzaLab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/Bt1jE2Vs…

Sep 2, 2020 · 18 shares · 15 followers View post →

Fernando Martin-Belmonte

@Fernand49142950 · X

Very interesting work investigating AKG effect in health spam in mice Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/rvzB1a9WUe

Sep 2, 2020 · 2 likes · 177 followers View post →

Joan Miro-Blanch

@jmirobla · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/5Mkdz5BAIw

Sep 2, 2020 · 3 likes · 625 followers View post →

Raghav Ramabadran

@BMSplice · X

RT @FrezzaLab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/Bt1jE2Vs…

Sep 2, 2020 · 18 shares · 195 followers View post →

Kelly A. Hogan Ph.D.

@Loose_Lab_Rat · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/VQwVlW8VHP

Sep 2, 2020 · 1 like · 1 share · 2,240 followers View post →

Jun-Liszt Li

@poppingjun · X

RT @FrezzaLab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/Bt1jE2Vs…

Sep 2, 2020 · 18 shares · 1,021 followers View post →

いと

@ponponpokotin · X

ぜひこの代謝前のアルギニンでも辿ってほしい。それで同等の効果が示されれば…ごくり……。。 Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice: Cell Metabolism https://t.co/6MTbVhqNOp

Sep 2, 2020 · 1 like · 395 followers View post →

Anika Wagner

@anikaewagner · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends #Lifespan and Compresses Morbidity in #Aging Mice https://t.co/6jo33jdQ2I

Sep 2, 2020 · 2 likes · 324 followers View post →

Martin Denzel

@MartinD79 · X

RT @MyAgeGroup: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in #Aging Mice L.P. https://t.co/…

Sep 2, 2020 · 4 shares · 2,911 followers View post →

Giorgia D’Este

@GiorgiaDeste · X

RT @FrezzaLab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/Bt1jE2Vs…

Sep 2, 2020 · 18 shares · 171 followers View post →

Felix Zajitschek

@zajitschek · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/yM3sqUQBVV

Sep 2, 2020 · 239 followers View post →

LIB

@L_I_B · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice: Cell Metabolism https://t.co/STIFsnz7f0

Sep 2, 2020 · 2,155 followers View post →

Nutriop Longevity

@nutriop · X

Alpha-Ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice #DrugAge https://t.co/1Cns1EZvXu https://t.co/bUnCwRGVqf

Sep 2, 2020 · 80 followers View post →

BrainEnergyMetabolism

@BrainMetabolism · X

Having your CaAKG and eating it too! Alpha-ketoglutarate improves healthspan in mice @Cell_Metabolism ? by suppressing inflammation? https://t.co/qcUWc46wwu https://t.co/pJuVpnNVTD

Sep 2, 2020 · 1,251 followers View post →

Eve Beavers

@espacetimeCO · X

RT @FrezzaLab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/Bt1jE2Vs…

Sep 2, 2020 · 18 shares · 900 followers View post →

Isabelle ADER

@isaperarnau · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice - ScienceDirect https://t.co/H7gVlirBBj

Sep 2, 2020 · 1 like · 492 followers View post →

MyAgeGroup

@MyAgeGroup · X

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in #Aging Mice L.P. https://t.co/lhOFLpsv6J

Sep 1, 2020 · 3 likes · 4 shares · 1,549 followers View post →

Dr. Helen E. Collins

@DrHelenECollin1 · X

RT @FrezzaLab: Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice https://t.co/Bt1jE2Vs…

Sep 1, 2020 · 18 shares · 2,203 followers View post →

Eleanor Sheekey

@EleanorSheekey · X

RT @Rejuvant: Thanks @EleanorSheekey for the wonderful video about our first publication in Cell Metabolism... Cheers to the Sheekey Scienc…

Sep 1, 2020 · 1 share · 4,885 followers View post →

Ret Serofer

@retserofer · X

@davidasinclair @Cell_Metabolism @BuckInstitute Well explained for laymen (like me) here: https://t.co/rxYgGU1Lxl

Sep 1, 2020 · 25 likes · 1 share · 1,305 followers View post →

The Science to Resist Aging

@Rejuvant · X

Thanks @EleanorSheekey for the wonderful video about our first publication in Cell Metabolism... Cheers to the Sheekey Science Show! https://t.co/k8PnIvBZfE

Sep 1, 2020 · 4 likes · 1 share · 235 followers View post →

shivani (she/her)

@algaevani · X

RT @EleanorSheekey: Latest video --> CaAKG - the healthspan extender you need to know about? https://t.co/MheNgLZuAj via @YouTube #aging #b…

Sep 1, 2020 · 1 share · 989 followers View post →

Eleanor Sheekey

@EleanorSheekey · X

Latest video --> CaAKG - the healthspan extender you need to know about? https://t.co/MheNgLZuAj via @YouTube #aging #biochemistry #AKG #alphaketoglutarate #healthspan #scicomm #longevity

Sep 1, 2020 · 6 likes · 1 share · 4,885 followers View post →

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.

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