Publications by authors named "Christopher D Willey"

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No differences in therapeutic efficacy while sparing healthy tissue for orthotopic glioblastoma patient-derived xenografts in context of proton FLASH.
Taylor L Schanel, Manoj Kumar, Lauren C Nassour-Caswell, Sreelakshmi Cherakara, Rhea Pandit, Christopher D Willey

Clin Transl Radiat Oncol· January 2026

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Induro-seq to analyze subcellular enrichment of small RNAs.
Monima Anam, Xisheng Liu, Taylor L Schanel, Christopher D Willey, Zhangli Su

Methods Enzymol· December 2025

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Preoperative Stereotactic Radiosurgery for Brain Metastases: A Phase 1 Dose Escalation Study Demonstrating Reduced Leptomeningeal Disease.
John M Hoyle, James M Markert, Kristen O Riley, Christopher D Willey, Samuel R Marcrom

Adv Radiat Oncol· November 2025

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Frameless linac-based radiosurgery for benign intracranial tumors treated with HyperArc: analysis of tumor control and toxicity.
Whitney S Hotsinpiller, Evan M Thomas, Ian Tsekouras, Richard A Popple, Markus Bredel, Christopher D Willey

J Neurooncol· October 2025

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Requirements and Study Design for the Next Proton FLASH Clinical Trials: an International Multidisciplinary Delphi Consensus.
Yvonne L B Klaver, Mischa S Hoogeman, Q Richard Lu, Jeffrey D Bradley, J Isabelle Choi, Christopher D Willey

Int J Radiat Oncol Biol Phys· September 2025

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A Novel Serum-Free Triculture Model of Glioblastoma, Astrocytes, and Macrophages.
Hasan Alrefai, Lauren C Nassour-Caswell, Manoj Kumar, Benjamin Lin, Taylor L Schanel, Christopher D Willey

Int J Mol Sci· September 2025

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Acquired resistance in cancer: towards targeted therapeutic strategies.
Alice Soragni, Erik S Knudsen, Thomas N O'Connor, Cristina E Tognon, Jeffrey W Tyner, Christopher D Willey

Nat Rev Cancer· August 2025

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Xenoline-polarized macrophages as an alternative in vitro model of tumor-associated macrophages in glioblastoma.
Hasan Alrefai, Benjamin Lin, Amr Elkholy, Manoj Kumar, Taylor L Schanel, Christopher D Willey

Acta Neuropathol Commun· June 2025

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Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma.
Benjamin Lin, Abigail K Shelton, Erin Smithberger, Julia Ziebro, Kasey R Skinner, Christopher D Willey

Acta Neuropathol Commun· June 2025

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KinoViz: A User-Friendly Web Application for High-Throughput Kinome Profiling Analysis and Visualization in Cancer Research.
Ehsan Saghapour, Joshua C Anderson, Jake Y Chen, Christopher D Willey

Res Sq· June 2025

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Xenoline-polarized macrophages as a physiologically relevant in vitro model of tumor-associated macrophages in glioblastoma.
Hasan Alrefai, Benjamin Lin, Amr Elkohly, Manoj Kumar, Taylor L Schanel, Christopher D Willey

Res Sq· May 2025

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IDH status dictates oHSV mediated metabolic reprogramming affecting anti-tumor immunity.
Upasana Sahu, Matthew P Mullarkey, Sara A Murphy, Joshua C Anderson, Vasanta Putluri, Christopher D Willey

Nat Commun· April 2025

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Altering fractionation during radiation overcomes radio-resistance in patient-derived glioblastoma cells assessed using a novel longitudinal radiation cytotoxicity assay.
Lauren C Nassour-Caswell, Manoj Kumar, Christian T Stackhouse, Hasan Alrefai, Taylor L Schanel, Christopher D Willey

Radiother Oncol· January 2025

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A High-Throughput Neurosphere-Based Colony Formation Assay to Test Drug and Radiation Sensitivity of Different Patient-Derived Glioblastoma Lines.
Manoj Kumar, Lauren C Nassour-Caswell, Hasan Alrefai, Joshua C Anderson, Taylor L Schanel, Christopher D Willey

Cells· December 2024

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Exploring Gut Microbiota Alterations with Trimethoprim-Sulfamethoxazole and Dexamethasone in a Humanized Microbiome Mouse Model.
George B H Green, Alexis N Cox-Holmes, Olivia Backan, Olivia Valbak, Anna Claire E Potier, Christopher D Willey

Microorganisms· May 2024

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Explorative Discovery of Gene Signatures and Clinotypes in Glioblastoma Cancer Through GeneTerrain Knowledge Map Representation.
Ehsan Saghapour, Zongliang Yue, Rahul Sharma, Sidharth Kumar, Zhandos Sembay, Christopher D Willey

bioRxiv· April 2024

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Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations.
Amber N Habowski, Deepthi P Budagavi, Sandra D Scherer, Arin B Aurora, Giuseppina Caligiuri, Christopher D Willey

Cancers (Basel)· January 2024

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Understanding the Effect of Prescription Isodose in Single-Fraction Stereotactic Radiosurgery on Plan Quality and Clinical Outcomes for Solid Brain Metastases.
Matthew H Brown, Samuel R Marcrom, Mayank P Patel, Richard A Popple, Roman L Travis, Christopher D Willey

Neurosurgery· December 2023

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Carmofur prevents cell cycle progression by reducing E2F8 transcription in temozolomide-resistant glioblastoma cells.
Cyntanna C Hawkins, Amber B Jones, Emily R Gordon, Yuvika Harsh, Julia K Ziebro, Christopher D Willey

Cell Death Discov· December 2023

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Correction: Chen et al. Targeted Extracellular Vesicles Delivered Verrucarin A to Treat Glioblastoma. 2022, , 130.
Kai Chen, Yingnan Si, Jia-Shiung Guan, Zhuoxin Zhou, Seulhee Kim, Christopher D Willey

Biomedicines· December 2023

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Tumor Treating Fields Alter the Kinomic Landscape in Glioblastoma Revealing Therapeutic Vulnerabilities.
Amber B Jones, Taylor L Schanel, Mikayla R Rigsby, Corinne E Griguer, Braden C McFarland, Christopher D Willey

Cells· August 2023

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Using 3D-bioprinted models to study pediatric neural crest-derived tumors.
Colin H Quinn, Andee M Beierle, Janet R Julson, Michael E Erwin, Hasan Alrefai, Christopher D Willey

Int J Bioprint· March 2023

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A path to translation: How 3D patient tumor avatars enable next generation precision oncology.
Shree Bose, Margarida Barroso, Milan G Chheda, Hans Clevers, Elena Elez, Christopher D Willey

Cancer Cell· December 2022

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An in vivo model of glioblastoma radiation resistance identifies long noncoding RNAs and targetable kinases.
Christian T Stackhouse, Joshua C Anderson, Zongliang Yue, Thanh Nguyen, Nicholas J Eustace, Christopher D Willey

JCI Insight· August 2022

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Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling.
Hongxing Shen, Fengyuan Huang, Xiangmin Zhang, Oluwagbemiga A Ojo, Yuebin Li, Christopher D Willey

Nat Commun· August 2022

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