Publications by authors named "Christopher Heaphy"

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RECQL4 alterations in gliomas and nerve sheath tumors: Expression patterns and therapeutic implications.
Sarra Belakhoua, Gianluca Lopez, Swati Dubey, Simran Rai, Liam Chen, Christopher M Heaphy

J Neuropathol Exp Neurol· December 2025

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Recurrent BEND2 Fusion Genes Identified by Whole Transcriptome Sequencing of Nonfunctional Pancreatic Neuroendocrine Tumors Correlate With Poor Patient Prognosis.
Michelle A Wood-Trageser, C Tolson Nichols, Danielle A Hutchings, Diana Bell, Abigail I Wald, Christopher M Heaphy

Mod Pathol· October 2025

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Loss of DAXX/ATRX Protein Expression Results in Ischemia Resistance and Radiation Sensitivity in Pancreatic Neuroendocrine Tumor Cells and Is Associated with Improved Response to Trans-Arterial Radioembolization.

Neuroendocrinology· September 2025

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Distinct malignant cell states and myeloid glutamate signaling associated with aggressive pancreatic neuroendocrine tumors.
Jeanna M Arbesfeld-Qiu, Jae-Won Cho, Phuong T T Nguyen, Nicole A Lester, Jennifer Su, Christopher M Heaphy

bioRxiv· July 2025

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Management of patients with small pancreatic neuroendocrine tumors from a biomarker and surgical perspective.
Anna Vera D Verschuur, Lin Chen, Els J Nieveen van Dijkum, Claudio Luchini, Thorvardur R Halfdanarson, Christopher M Heaphy

Endocr Relat Cancer· May 2025

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Detection of Alternative Lengthening of Telomeres via Chromogenic In Situ Hybridization for the Prognostication of PanNETs and Other Neoplasms.
Christopher M Heaphy, Simmi Patel, Katelyn Smith, Anne R Wondisford, Michelle L Lynskey

Mod Pathol· March 2025

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Gradual telomere shortening in the tumorigenesis of pancreatic and hepatic mucinous cystic neoplasms.
You-Na Sung, Marija Stojanova, Seungbeom Shin, HyungJun Cho, Christopher M Heaphy

Hum Pathol· October 2024

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The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres.
Mindy K Graham, Beisi Xu, Christine Davis, Alan K Meeker, Christopher M Heaphy

Cancer Res Commun· June 2024

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Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer.
Joakin O Mori, Isra Elhussin, W Nathaniel Brennen, Mindy K Graham, Tamara L Lotan, Christopher M Heaphy

Nat Rev Urol· May 2024

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Longer prostate stromal cell telomere length is associated with increased risk of death from other cancers.
Joakin O Mori, Elizabeth A Platz, Jiayun Lu, Alexandria Brame, Misop Han, Christopher M Heaphy

Front Med (Lausanne)· May 2024

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Chromogenic detection of telomere lengths in situ aids the identification of precancerous lesions in the prostate.
Onur Ertunc, Erica Smearman, Qizhi Zheng, Jessica L Hicks, Jacqueline A Brosnan-Cashman, Christopher M Heaphy

Prostate· February 2024

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DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.
Lia M Pinto, Alexandros Pailas, Max Bondarchenko, Abhishek Bharadwaj Sharma, Katrin Neumann, Christopher M Heaphy

Nucleic Acids Res· February 2024

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Alternative lengthening of telomeres: mechanism and the pathogenesis of cancer.
Joakin O Mori, Joshua Keegan, Rachel L Flynn, Christopher M Heaphy

J Clin Pathol· January 2024

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Predicting recurrence in pancreatic neuroendocrine tumours: role of ARX and alternative lengthening of telomeres (ALT).
Azfar Neyaz, Rory Crotty, Steffen Rickelt, Amaya Pankaj, Marija Stojanova, Christopher M Heaphy

Histopathology· October 2023

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Chromogenic detection of telomere lengths in situ aids the identification of precancerous lesions in the prostate.
Onur Ertunc, Erica Smearman, Qizhi Zheng, Jessica L Hicks, Jacqueline A Brosnan-Cashman, Christopher M Heaphy

bioRxiv· April 2023

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Reprint of: The Diagnostic and Prognostic Utility of Incorporating DAXX, ATRX, and Alternative Lengthening of Telomeres (ALT) to the Evaluation of Pancreatic Neuroendocrine Tumors (PanNETs).
Christopher M Heaphy, Aatur D Singhi

Hum Pathol· February 2023

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Genomic Characterization of Prostatic Basal Cell Carcinoma.
Jin-Yih Low, Minjeong Ko, Brian Hanratty, Radhika A Patel, Akshay Bhamidipati, Christopher M Heaphy

Am J Pathol· January 2023

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Novel plasma exosome biomarkers for prostate cancer progression in co-morbid metabolic disease.
Naser Jafari, Andrew Chen, Manohar Kolla, Isabella R Pompa, Yuhan Qiu, Christopher M Heaphy

Adv Cancer Biol Metastasis· December 2022

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The diagnostic and prognostic utility of incorporating DAXX, ATRX, and alternative lengthening of telomeres to the evaluation of pancreatic neuroendocrine tumors.
Christopher M Heaphy, Aatur D Singhi

Hum Pathol· November 2022

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The prostate tissue-based telomere biomarker as a prognostic tool for metastasis and death from prostate cancer after prostatectomy.
Christopher M Heaphy, Corinne E Joshu, John R Barber, Christine Davis, Jiayun Lu

J Pathol Clin Res· September 2022

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Prognostic and Predictive Biomarkers for Pancreatic Neuroendocrine Tumors.
Wenzel M Hackeng, Hussein A Assi, Florine H M Westerbeke, Lodewijk A A Brosens, Christopher M Heaphy

Surg Pathol Clin· September 2022

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Mutational Landscape and Outcomes of Conjunctival Melanoma in 101 Patients.
Sara E Lally, Tatyana Milman, Marlana Orloff, Lauren A Dalvin, Charles G Eberhart, Christopher M Heaphy

Ophthalmology· June 2022

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Novel forms of prostate cancer chemoresistance to successful androgen deprivation therapy demand new approaches: Rationale for targeting BET proteins.
Joakin O Mori, Jordan S Shafran, Marija Stojanova, Mark H Katz, Gretchen A Gignac, Christopher M Heaphy

Prostate· June 2022

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Therapeutic Vulnerability to ATR Inhibition in Concurrent and -Deficient/ALT-Positive High-Grade Solid Tumors.
Ming Yuan, Charles G Eberhart, Christine A Pratilas, Jaishri O Blakeley, Christine Davis, Christopher M Heaphy

Cancers (Basel)· June 2022

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Correction: Absence of Cytomegalovirus in Glioblastoma and Other High-grade Gliomas by Real-time PCR, Immunohistochemistry, and In Situ Hybridization.
Matthias Holdhoff, Gunes Guner, Fausto J Rodriguez, Jessica L Hicks, Qizhi Zheng, Christopher M Heaphy

Clin Cancer Res· April 2022

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