Publications by authors named "Wenzel M Hackeng"

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Should we worry about high-grade pancreatic neuroendocrine tumor progression and alkylating agents?.
Wenzel M Hackeng, Koen Ma Dreijerink, Lodewijk Aa Brosens

J Pathol· May 2025

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Clinical Relevance of ATRX/DAXX Gene Mutations and ALT in Functioning Pancreatic Neuroendocrine Tumors.
Brenna R van T Veld, Wenzel M Hackeng, Claudio Luchini, Lodewijk A A Brosens, Koen M A Dreijerink

Endocr Pathol· February 2025

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Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres).
Paola Mattiolo, Michele Bevere, Andrea Mafficini, Anna Vera D Verschuur, Martina Calicchia, Wenzel M Hackeng

Endocr Pathol· December 2024

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DNA Methylation Profiling Enables Accurate Classification of Nonductal Primary Pancreatic Neoplasms.
Anna Vera D Verschuur, Wenzel M Hackeng, Florine Westerbeke, Jamal K Benhamida, Olca Basturk

Clin Gastroenterol Hepatol· June 2024

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Druggable growth dependencies and tumor evolution analysis in patient-derived organoids of neuroendocrine neoplasms from multiple body sites.
Talya L Dayton, Nicolas Alcala, Laura Moonen, Lisanne den Hartigh, Veerle Geurts, Wenzel M Hackeng

Cancer Cell· December 2023

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Diagnostic Utility of Menin Immunohistochemistry in Patients With Multiple Endocrine Neoplasia Type 1 Syndrome.
Anna Vera D Verschuur, Aranxa S M Kok, Folkert H M Morsink, Wendy W J de Leng, Medard F M van den Broek, Wenzel M Hackeng

Am J Surg Pathol· July 2023

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Aggressive versus indolent insulinomas: new clinicopathological insights.
Wenzel M Hackeng, Lodewijk A A Brosens, Koen M A Dreijerink

Endocr Relat Cancer· May 2023

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Prognostic and Predictive Biomarkers for Pancreatic Neuroendocrine Tumors.
Wenzel M Hackeng, Hussein A Assi, Florine H M Westerbeke, Lodewijk A A Brosens, Christopher M Heaphy

Surg Pathol Clin· September 2022

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The Impact of Clinical and Pathological Features on Intraductal Papillary Mucinous Neoplasm Recurrence After Surgical Resection: Long-Term Follow-Up Analysis.
Michael J Pflüger, James F Griffin, Wenzel M Hackeng, Satomi Kawamoto, Jun Yu

Ann Surg· June 2022

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Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size.
Wenzel M Hackeng, Lodewijk A A Brosens, Joo Young Kim, Roderick O'Sullivan, You-Na Sung

Gut· May 2022

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Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System.
Shinichi Yachida, Yasushi Totoki, Michaël Noë, Yoichiro Nakatani, Masafumi Horie, Wenzel M Hackeng

Cancer Discov· March 2022

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Metastatic Patterns of Duodenopancreatic Neuroendocrine Tumors in Patients With Multiple Endocrine Neoplasia Type 1.
Wenzel M Hackeng, Dirk-Jan van Beek, Aranxa S M Kok, Madelon van Emst, Folkert H M Morsink

Am J Surg Pathol· February 2022

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Clinical implications of cell-of-origin epigenetic characteristics in non-functional pancreatic neuroendocrine tumors.
Koen Ma Dreijerink, Wenzel M Hackeng, Aatur D Singhi, Christopher M Heaphy, Lodewijk Aa Brosens

J Pathol· February 2022

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Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer.
Paloma Cejas, Yingtian Xie, Alba Font-Tello, Klothilda Lim, Sudeepa Syamala, Wenzel M Hackeng

Nat Commun· October 2021

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A Parathyroid-Gut Axis: Hypercalcemia and the Pathogenesis of Gastrinoma in Multiple Endocrine Neoplasia 1.
Wenzel M Hackeng, Koen M A Dreijerink, G Johan A Offerhaus, Lodewijk A A Brosens

Mol Cancer Res· June 2021

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Genome Methylation Accurately Predicts Neuroendocrine Tumor Origin: An Online Tool.
Wenzel M Hackeng, Koen M A Dreijerink, Wendy W J de Leng, Folkert H M Morsink, Gerlof D Valk

Clin Cancer Res· March 2021

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The Management of Neuroendocrine Tumors of the Lung in MEN1: Results From the Dutch MEN1 Study Group.
Medard F M van den Broek, Joanne M de Laat, Rachel S van Leeuwaarde, Annenienke C van de Ven, Wouter W de Herder, Wenzel M Hackeng

J Clin Endocrinol Metab· January 2021

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Genomic characterization of malignant progression in neoplastic pancreatic cysts.
Michaël Noë, Noushin Niknafs, Catherine G Fischer, Wenzel M Hackeng, Violeta Beleva Guthrie

Nat Commun· August 2020

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The decisive role of molecular pathology in presumed somatic metastases of type II testicular germ cell tumors: report of 2 cases.
Mariëtte E G Kranendonk, Wenzel M Hackeng, G Johan A Offerhaus, Folkert H M Morsink, Geertruida N Jonges

Diagn Pathol· July 2020

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Alternative Lengthening of Telomeres and Differential Expression of Endocrine Transcription Factors Distinguish Metastatic and Non-metastatic Insulinomas.
Wenzel M Hackeng, Willemien Schelhaas, Folkert H M Morsink, Charlotte M Heidsma, Susanne van Eeden

Endocr Pathol· June 2020

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Assessment of ARX expression, a novel biomarker for metastatic risk in pancreatic neuroendocrine tumors, in endoscopic ultrasound fine-needle aspiration.
Wenzel M Hackeng, Folkert H M Morsink, Leon M G Moons, Christopher M Heaphy, G Johan A Offerhaus

Diagn Cytopathol· April 2020

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Clear cell chondrosarcoma in Von Hippel-Lindau disease.
Koen M A Dreijerink, Rachel S van Leeuwaarde, Wenzel M Hackeng, Rachel H Giles, Wendy W J de Leng

Fam Cancer· January 2020

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Well-differentiated Pancreatic Neuroendocrine Tumor in a Patient With Familial Atypical Multiple Mole Melanoma Syndrome (FAMMM).
Michaël Noë, Wenzel M Hackeng, Wendy W J de Leng, Menno Vergeer, Frank P Vleggaar

Am J Surg Pathol· September 2019

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Pseudomyxoma Peritonei After a Total Pancreatectomy for Intraductal Papillary Mucinous Neoplasm With Colloid Carcinoma in Lynch Syndrome.
Wenzel M Hackeng, Livia E V M de Guerre, Karel C Kuypers, Alexander M Snoek, Folkert H Morsink

Pancreas· January 2019

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Morphology and genetics of pyloric gland adenomas in familial adenomatous polyposis.
Wenzel M Hackeng, Elizabeth A Montgomery, Francis M Giardiello, Aatur D Singhi, Marija Debeljak

Histopathology· March 2017

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