Publications by authors named "Christopher Hupfeld"

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SGLT2 Inhibitor-Induced Low-Grade Ketonemia Ameliorates Retinal Hypoxia in Diabetic Retinopathy-A Novel Hypothesis.
Sunder Mudaliar, Christopher Hupfeld, Daniel L Chao

J Clin Endocrinol Metab· April 2021

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Sodium-Glucose Cotransporter Type 2 (SGLT-2) Inhibitors and Ketogenesis: the Good and the Bad.
Preethika Ekanayake, Christopher Hupfeld, Sunder Mudaliar

Curr Diab Rep· November 2020

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VISUAL VIGNETTE.
Brad H Kimura, Farhad Farjoudi, Christopher J Hupfeld

Endocr Pract· August 2019

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Navigating the "MACE" in Cardiovascular Outcomes Trials and decoding the relevance of Atherosclerotic Cardiovascular Disease benefits versus Heart Failure benefits.
Christopher Hupfeld, Sunder Mudaliar

Diabetes Obes Metab· August 2019

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Regulation of receptor tyrosine kinase signaling by GRKs and beta-arrestins.
Christopher J Hupfeld, Jerrold M Olefsky

Annu Rev Physiol· April 2007

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G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes.
Isao Usui, Takeshi Imamura, Jennie L Babendure, Hiroaki Satoh, Juu-Chin Lu, Christopher J Hupfeld

Mol Endocrinol· November 2005

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Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes.
Jin Zhang, Christopher J Hupfeld, Susan S Taylor, Jerrold M Olefsky, Roger Y Tsien

Nature· September 2005

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Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors.
Christopher J Hupfeld, Jamie L Resnik, Satoshi Ugi, Jerrold M Olefsky

J Biol Chem· January 2005

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beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1.
Isao Usui, Takeshi Imamura, Jie Huang, Hiroaki Satoh, Sudha K Shenoy, Christopher J Hupfeld

Mol Cell Biol· October 2004

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GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation.
Isao Usui, Takeshi Imamura, Hiroaki Satoh, Jie Huang, Jennie L Babendure, Christopher J Hupfeld

EMBO J· July 2004

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Current recommendations for prevention of cardiovascular disease in patients with diabetes mellitus. Part II of II.
Christopher J Hupfeld, Gail A Wong

Prev Cardiol· April 2003

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Beta -Arrestin 1 down-regulation after insulin treatment is associated with supersensitization of beta 2 adrenergic receptor Galpha s signaling in 3T3-L1 adipocytes.
Christopher J Hupfeld, Stephane Dalle, Jerrold M Olefsky

Proc Natl Acad Sci U S A· January 2003

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Molecular mechanisms of diabetic cardiovascular disease.
Christopher J Hupfeld, Gail A Wong

Prev Cardiol· December 2002

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Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1.
Stéphane Dalle, Takeshi Imamura, David W Rose, Dorothy Sears Worrall, Satoshi Ugi, Christopher J Hupfeld

Mol Cell Biol· September 2002

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