Publications by authors named "Christopher J Handley"

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Extracellular matrix proteins interact with cell-signaling pathways in modifying risk of achilles tendinopathy.
Colleen J Saunders, Lize van der Merwe, Jill Cook, Christopher J Handley, Malcolm Collins

J Orthop Res· June 2015

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Variants within the COMP and THBS2 genes are not associated with Achilles tendinopathy in a case-control study of South African and Australian populations.
Colleen J Saunders, Lize Van Der Merwe, Jill Cook, Christopher J Handley, Malcolm Collins

J Sports Sci· January 2015

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Polymorphic variation within the ADAMTS2, ADAMTS14, ADAMTS5, ADAM12 and TIMP2 genes and the risk of Achilles tendon pathology: a genetic association study.
Louis El Khoury, Michael Posthumus, Malcolm Collins, Christopher J Handley, Jill Cook

J Sci Med Sport· November 2013

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Association of type XI collagen genes with chronic Achilles tendinopathy in independent populations from South Africa and Australia.
Melanie Hay, Jon Patricios, Robert Collins, Andy Branfield, Jill Cook, Christopher J Handley

Br J Sports Med· June 2013

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Investigation of variants within the COL27A1 and TNC genes and Achilles tendinopathy in two populations.
Colleen J Saunders, Lize van der Merwe, Michael Posthumus, Jill Cook, Christopher J Handley

J Orthop Res· April 2013

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The apoptosis pathway and the genetic predisposition to Achilles tendinopathy.
Erica-Mari Nell, Lize van der Merwe, Jill Cook, Christopher J Handley, Malcolm Collins

J Orthop Res· November 2012

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Short- and long-term exposure of articular cartilage to curcumin or quercetin inhibits aggrecan loss.
Eileen Lay, Tom Samiric, Christopher J Handley, Mirna Z Ilic

J Nutr Biochem· February 2012

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A pathway-based approach investigating the genes encoding interleukin-1β, interleukin-6 and the interleukin-1 receptor antagonist provides new insight into the genetic susceptibility of Achilles tendinopathy.
Alison V September, Erica-Mari Nell, Kevin O'Connell, Jill Cook, Christopher J Handley

Br J Sports Med· October 2011

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Effectiveness of intra-articular hyaluronan (Synvisc, hylan G-F 20) for the treatment of first metatarsophalangeal joint osteoarthritis: a randomised placebo-controlled trial.
Shannon E Munteanu, Gerard V Zammit, Hylton B Menz, Karl B Landorf, Christopher J Handley

Ann Rheum Dis· October 2011

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Components of the transforming growth factor-beta family and the pathogenesis of human Achilles tendon pathology--a genetic association study.
Michael Posthumus, Malcolm Collins, Jill Cook, Christopher J Handley, William J Ribbans

Rheumatology (Oxford)· November 2010

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Change in proteoglycan metabolism is a characteristic of human patellar tendinopathy.
John Parkinson, Tom Samiric, Mirna Z Ilic, Jill Cook, Julian A Feller, Christopher J Handley

Arthritis Rheum· October 2010

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Changes in the composition of the extracellular matrix in patellar tendinopathy.
Tom Samiric, John Parkinson, Mirna Z Ilic, Jill Cook, Julian A Feller, Christopher J Handley

Matrix Biol· May 2009

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Efficacy of intra-articular hyaluronan (Synvisc(R)) for the treatment of osteoarthritis affecting the first metatarsophalangeal joint of the foot (hallux limitus): study protocol for a randomised placebo controlled trial.
Shannon E Munteanu, Hylton B Menz, Gerard V Zammit, Karl B Landorf, Christopher J Handley

J Foot Ankle Res· January 2009

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Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice.
Mirna Z Ilic, Charlotte J East, Fraser M Rogerson, Amanda J Fosang, Christopher J Handley

J Biol Chem· December 2007

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Structure, metabolism, and tissue roles of chondroitin sulfate proteoglycans.
Christopher J Handley, Tom Samiric, Mirna Z Ilic

Adv Pharmacol· March 2007

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Sulfated polysaccharides inhibit the catabolism and loss of both large and small proteoglycans in explant cultures of tendon.
Tom Samiric, Mirna Z Ilic, Christopher J Handley

FEBS J· August 2006

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Proteoglycans and catabolic products of proteoglycans present in ligament.
Mirna Z Ilic, Phillip Carter, Alicia Tyndall, Jayesh Dudhia, Christopher J Handley

Biochem J· January 2005

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Large aggregating and small leucine-rich proteoglycans are degraded by different pathways and at different rates in tendon.
Tom Samiric, Mirna Z Ilic, Christopher J Handley

Eur J Biochem· September 2004

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Characterisation of proteoglycans and their catabolic products in tendon and explant cultures of tendon.
Tom Samiric, Mirna Z Ilic, Christopher J Handley

Matrix Biol· May 2004

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Selective inhibition of ADAMTS-1, -4 and -5 by catechin gallate esters.
Mireille N Vankemmelbeke, Gavin C Jones, Cyprianne Fowles, Mirna Z Ilic, Christopher J Handley

Eur J Biochem· June 2003

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Distribution of newly synthesized aggrecan in explant cultures of bovine cartilage treated with retinoic acid.
Christopher J Handley, Gavin M Winter, Mirna Z Ilic, Jacqueline M Ross, C Anthony Poole

Matrix Biol· November 2002

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Highly sulfated glycosaminoglycans inhibit aggrecanase degradation of aggrecan by bovine articular cartilage explant cultures.
Shannon E Munteanu, Mirna Z Ilic, Christopher J Handley

Matrix Biol· August 2002

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