Publications by authors named "Christopher Loewen"

Claim this Profile
R
Revealing function-altering MECP2 mutations in individuals with autism spectrum disorder using yeast and Drosophila.
Eric Chen, Jessica Schmitt, Graeme McIntosh, Barry P Young, Tianshun Lian, Christopher J R Loewen

Genetics· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-wide screen identifies new set of genes for improved heterologous laccase expression in Saccharomyces cerevisiae.
Garrett Strawn, Ryan W K Wong, Barry P Young, Michael Davey, Corey Nislow, Christopher J R Loewen

Microb Cell Fact· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.
Rosanne Persaud, Sheena C Li, Joseph D Chao, Roberto Forestieri, Elizabeth Donohue, Christopher J R Loewen

Cell Chem Biol· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Ist2 recruits the lipid transporters Osh6/7 to ER-PM contacts to maintain phospholipid metabolism.
Andrew King On Wong, Barry Paul Young, Christopher J R Loewen

J Cell Biol· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation.
Payel Ganguly, Landiso Madonsela, Jesse T Chao, Christopher J R Loewen, Timothy P O'Connor

PLoS Genet· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MAPS: machine-assisted phenotype scoring enables rapid functional assessment of genetic variants by high-content microscopy.
Jesse T Chao, Calvin D Roskelley, Christopher J R Loewen

BMC Bioinformatics· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Premalignant Cell-Based Model for Functionalization and Classification of Variants.
Jesse T Chao, Rocio Hollman, Warren M Meyers, Fabian Meili, Kenneth A Matreyek, Christopher J R Loewen

Cancer Res· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sentinel interaction mapping - a generic approach for the functional analysis of human disease gene variants using yeast.
Barry P Young, Kathryn L Post, Jesse T Chao, Fabian Meili, Kurt Haas, Christopher Loewen

Dis Model Mech· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.
Kathryn L Post, Manuel Belmadani, Payel Ganguly, Fabian Meili, Riki Dingwall, Christopher J R Loewen

Nat Commun· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
pH Biosensing by PI4P Regulates Cargo Sorting at the TGN.
John J H Shin, Peter Liu, Leslie J Chan, Azmat Ullah, Jingxi Pan, Christopher J R Loewen

Dev Cell· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mechanisms of PTPσ-Mediated Presynaptic Differentiation.
Claire Bomkamp, Nirmala Padmanabhan, Benyamin Karimi, Yuan Ge, Jesse T Chao, Christopher J R Loewen

Front Synaptic Neurosci· May 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Viral proteins as a potential driver of histone depletion in dinoflagellates.
Nicholas A T Irwin, Benjamin J E Martin, Barry P Young, Martin J G Browne, Andrew Flaus, Christopher J R Loewen

Nat Commun· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress.
Veena Mathew, Annie S Tam, Karissa L Milbury, Analise K Hofmann, Christopher S Hughes, Christopher J R Loewen

J Cell Biol· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes.
Matthew Hayes, Vineet Choudhary, Namrata Ojha, John Jh Shin, Gil-Soo Han, Christopher Jr Loewen

Microb Cell· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Histone Acetylation, Not Stoichiometry, Regulates Linker Histone Binding in .
Mackenzie B D Lawrence, Nicolas Coutin, Jennifer K Choi, Benjamin J E Martin, Nicholas A T Irwin, Christopher Loewen

Genetics· September 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Systematic identification of genes involved in metabolic acid stress resistance in yeast and their potential as cancer targets.
John J Shin, Qurratulain Aftab, Pamela Austin, Jennifer A McQueen, Tak Poon, Christopher J R Loewen

Dis Model Mech· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility.
Sophie A Comyn, Barry P Young, Christopher J Loewen, Thibault Mayor

PLoS Genet· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Global reorganization of budding yeast chromosome conformation in different physiological conditions.
Elisa Dultz, Harianto Tjong, Elodie Weider, Mareike Herzog, Barry Young, Christopher Loewen

J Cell Biol· February 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A role for the budding yeast separase, Esp1, in Ty1 element retrotransposition.
Krystina L Ho, Lina Ma, Stephanie Cheung, Savrina Manhas, Nancy Fang, Christopher Loewen

PLoS Genet· March 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria.
Sujoy Lahiri, Jesse T Chao, Shabnam Tavassoli, Andrew K O Wong, Vineet Choudhary, Christopher J R Loewen

PLoS Biol· October 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Barriers to uniformity within the endoplasmic reticulum.
Andrew K O Wong, Jesse T Chao, Christopher J R Loewen

Curr Opin Cell Biol· August 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Polarization of the endoplasmic reticulum by ER-septin tethering.
Jesse T Chao, Andrew K O Wong, Shabnam Tavassoli, Barry P Young, Adam Chruscicki, Christopher J R Loewen

Cell· July 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae.
Wayne R Riekhof, Wen-I Wu, Jennifer L Jones, Mrinalini Nikrad, Mallory M Chan, Christopher J R Loewen

J Biol Chem· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Balony: a software package for analysis of data generated by synthetic genetic array experiments.
Barry P Young, Christopher J R Loewen

BMC Bioinformatics· December 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Plasma membrane--endoplasmic reticulum contact sites regulate phosphatidylcholine synthesis.
Shabnam Tavassoli, Jesse T Chao, Barry P Young, Ruud C Cox, William A Prinz, Christopher J R Loewen

EMBO Rep· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis