Publications by authors named "Christopher McCann"

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Rerouting the drug response: Overcoming metabolic adaptation in KRAS-mutant cancers.
Deborah Y Moss, Christopher McCann, Emma M Kerr

Sci Signal· October 2022

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Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists.
Vera Grinkevitch, Mark Wappett, Nyree Crawford, Stacey Price, Andrea Lees, Christopher McCann

Mol Cancer Ther· April 2022

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Development of a protein signature to enable clinical positioning of IAP inhibitors in colorectal cancer.
Christopher McCann, Anna Matveeva, Katherine McAllister, Sandra Van Schaeybroeck, Tamas Sessler

FEBS J· September 2021

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Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer.
Nyree Crawford, Katie J Stott, Tamas Sessler, Christopher McCann, William McDaid

Mol Cancer Ther· September 2021

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Metabolic Reprogramming: A Friend or Foe to Cancer Therapy?
Christopher McCann, Emma M Kerr

Cancers (Basel)· July 2021

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Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant.
Michael Fichtner, Emir Bozkurt, Manuela Salvucci, Christopher McCann, Katherine A McAllister

Cell Death Dis· November 2020

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The pseudo-caspase FLIP(L) regulates cell fate following p53 activation.
Andrea Lees, Alexander J McIntyre, Nyree T Crawford, Fiammetta Falcone, Christopher McCann

Proc Natl Acad Sci U S A· July 2020

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A revised model of TRAIL-R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis.
Luke M Humphreys, Jennifer P Fox, Catherine A Higgins, Joanna Majkut, Tamas Sessler, Christopher McCann

EMBO Rep· March 2020

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Heterogeneous responses to low level death receptor activation are explained by random molecular assembly of the Caspase-8 activation platform.
Anna Matveeva, Michael Fichtner, Katherine McAllister, Christopher McCann, Marc Sturrock

PLoS Comput Biol· September 2019

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Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists.
Christopher McCann, Nyree Crawford, Joanna Majkut, Caitriona Holohan, Chris W D Armstrong

Cell Death Dis· October 2018

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Detection of physiological deterioration by the SNAP40 wearable device compared to standard monitoring devices in the emergency department: the SNAP40-ED study.
Matthew J Reed, Megan McGrath, Polly L Black, Steff Lewis, Christopher McCann

Diagn Progn Res· September 2018

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PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy.
Chris W D Armstrong, Pamela J Maxwell, Chee Wee Ong, Kelly M Redmond, Christopher McCann

Oncotarget· February 2016

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Dying other, dying self: creating culture and meaning in palliative healthcare.
Christopher J McCann, Hector Y Adames

Palliat Support Care· August 2013

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Abnormal cytology in 2012: management of atypical squamous cells, low-grade intraepithelial neoplasia, and high-grade intraepithelial neoplasia.
Leslie A Garrett, Christopher K McCann

Clin Obstet Gynecol· March 2013

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Laparoscopic surgical staging of early ovarian cancer.
Sarah Weber, Christopher K McCann, David M Boruta, John O Schorge, Whitfield B Growdon

Rev Obstet Gynecol· October 2012

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Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.
Christopher K McCann, Whitfield B Growdon, Kashmira Kulkarni-Datar, Michael D Curley, Anne M Friel

PLoS One· April 2012

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Evolution of surgical management of early-stage endometrial cancer.
David M Boruta, Whitfield B Growdon, Christopher K McCann, Leslie A Garrett, Marcela G del Carmen

Am J Obstet Gynecol· December 2011

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Prognostic significance of splenectomy as part of initial cytoreductive surgery in ovarian cancer.
Christopher K McCann, Whitfield B Growdon, Elizabeth G Munro, Marcela G Del Carmen, David M Boruta

Ann Surg Oncol· October 2011

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Surgical debulking of ovarian cancer: what difference does it make?
John O Schorge, Christopher McCann, Marcela G Del Carmen

Rev Obstet Gynecol· July 2011

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Prognostic determinants in patients with stage IIIC and IV uterine papillary serous carcinoma.
J Alejandro Rauh-Hain, Whitfield B Growdon, John O Schorge, A K Goodman, David M Boruta, Christopher McCann

Gynecol Oncol· November 2010

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Mouse models of uterine corpus tumors: clinical significance and utility.
Anne M Friel, Whitfield B Growdon, Christopher K McCann, Alexander B Olawaiye, Elizabeth G Munro

Front Biosci (Elite Ed)· June 2010

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