Publications by authors named "Christopher Nicol"

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Alexidine is a TAZ-specific small-molecule inhibitor that suppresses breast cancer invasion and metastasis.
Anni Ge, Lishui Niu, Rachel Rubino, Kimberly Seaman, Xin Song, Christopher J B Nicol

iScience· December 2025

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MassVision: An Open-Source End-to-End Platform for AI-Driven Mass Spectrometry Imaging Analysis.
Amoon Jamzad, Jade Warren, Ayesha Syeda, Martin Kaufmann, Natasha Iaboni, Christopher J B Nicol

Anal Chem· October 2025

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Evaluating rapid evaporative ionization mass spectrometry profiles of human breast cancer cells using a 3D in vitro assay.
Rachel E Rubino, Martin Kaufmann, Amoon Jamzad, Natasha Iaboni, Kevin Yi Mi Ren, Christopher J B Nicol

Anal Bioanal Chem· September 2025

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The α-MG exhibits neuroprotective potential by reducing amyloid beta peptide-induced inflammation, oxidative stress, and tau aggregation in human neural stem cells.
Ming-Chang Chiang, Christopher J B Nicol, Yu-Ping Yang, Tairui Chiang, Chiahui Yen

Brain Res· April 2025

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A Review of the Neuroprotective Properties of Exosomes Derived from Stem Cells and Exosome-Coated Nanoparticles for Treating Neurodegenerative Diseases and Stroke.
Yu-Ping Yang, Christopher J B Nicol, Ming-Chang Chiang

Int J Mol Sci· April 2025

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Protective effects of resveratrol against PM-induced damage in hNSCs and its mitigation of PM-induced mitochondrial dysfunction in a 3D scaffold system.
Ming-Chang Chiang, Christopher J B Nicol, Yu-Ping Yang, Tairui Chiang, Chiahui Yen

Neuroscience· March 2025

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Resveratrol-Enhanced Human Neural Stem Cell-Derived Exosomes Mitigate MPP+-Induced Neurotoxicity Through Activation of AMPK and Nrf2 Pathways and Inhibition of the NLRP3 Inflammasome in SH-SY5Y Cells.
Ming-Chang Chiang, Yu-Ping Yang, Christopher J B Nicol, Tairui Chiang, Chiahui Yen

Life (Basel)· February 2025

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A Novel Bioluminescent Biosensor Quantifying Intramolecular Interaction and Levels of Pyroptosis Effector GSDMD.
Tynan Kelly, Simran Bhandari, Madeleine Carew, Rachel Rubino, Christopher Nicol

Cells· September 2024

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Identification of PTPN12 Phosphatase as a Novel Negative Regulator of Hippo Pathway Effectors YAP/TAZ in Breast Cancer.
Sahar Sarmasti Emami, Anni Ge, Derek Zhang, Yawei Hao, Min Ling, Christopher J B Nicol

Int J Mol Sci· April 2024

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Gold Nanoparticles in Neurological Diseases: A Review of Neuroprotection.
Ming-Chang Chiang, Yu-Ping Yang, Christopher J B Nicol, Chieh-Ju Wang

Int J Mol Sci· February 2024

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Development of Novel Bioluminescent Biosensors Monitoring the Conformation and Activity of the Merlin Tumour Suppressor.
Alexander Pipchuk, Tynan Kelly, Madeleine Carew, Christopher Nicol, Xiaolong Yang

Int J Mol Sci· January 2024

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Molecular characterization of human peripheral nerves using desorption electrospray ionization mass spectrometry imaging.
Diane Tomalty, Olivia Giovannetti, Leah Velikonja, Jasica Munday, Martin Kaufmann, Christopher J B Nicol

J Anat· November 2023

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Metabolically Active Zones Involving Fatty Acid Elongation Delineated by DESI-MSI Correlate with Pathological and Prognostic Features of Colorectal Cancer.
Martin Kaufmann, Natasha Iaboni, Amoon Jamzad, David Hurlbut, Kevin Yi Mi Ren, Christopher J B Nicol

Metabolites· March 2023

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Resveratrol Mitigates Oxygen and Glucose Deprivation-Induced Inflammation, NLRP3 Inflammasome, and Oxidative Stress in 3D Neuronal Culture.
Ming-Chang Chiang, Christopher J B Nicol, Shy-Shyong Lo, Shiang-Wei Hung, Chieh-Ju Wang

Int J Mol Sci· October 2022

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GSH-AuNP anti-oxidative stress, ER stress and mitochondrial dysfunction in amyloid-beta peptide-treated human neural stem cells.
Ming-Chang Chiang, Christopher J B Nicol

Free Radic Biol Med· July 2022

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Targeting the Ezrin Adaptor Protein Sensitizes Metastatic Breast Cancer Cells to Chemotherapy and Reduces Neoadjuvant Therapy-induced Metastasis.
Victoria Hoskin, Abdi Ghaffari, Brian J Laight, Sandip SenGupta, Yolanda Madarnas, Christopher J B Nicol

Cancer Res Commun· June 2022

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Novel MicroRNA-Regulated Transcript Networks Are Associated with Chemotherapy Response in Ovarian Cancer.
Danai G Topouza, Jihoon Choi, Sean Nesdoly, Anastasiya Tarnouskaya, Christopher J B Nicol

Int J Mol Sci· April 2022

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Exposure to PM induces neurotoxicity, mitochondrial dysfunction, oxidative stress and inflammation in human SH-SY5Y neuronal cells.
Chien-Hung Lin, Christopher J B Nicol, Chuan Wan, Shiang-Jiuun Chen, Rong-Nan Huang

Neurotoxicology· January 2022

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TO901317 activation of LXR-dependent pathways mitigate amyloid-beta peptide-induced neurotoxicity in 3D human neural stem cell culture scaffolds and AD mice.
Ming-Chang Chiang, Christopher J B Nicol, Shiang-Jiuun Chen, Rong-Nan Huang

Brain Res Bull· January 2022

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Nanogold induces anti-inflammation against oxidative stress induced in human neural stem cells exposed to amyloid-beta peptide.
Ming-Chang Chiang, Christopher J B Nicol, Chien-Hung Lin, Shiang-Jiuun Chen, Chiahui Yen

Neurochem Int· May 2021

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A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells.
Xiaojing Yang, Jina Nanayakkara, Duncan Claypool, Sadegh Saghafinia, Justin J M Wong, Christopher J B Nicol

Sci Rep· May 2021

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Correction: 15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection.
Robert J Evans, Katherine Pline, Catherine A Loynes, Sarah Needs, Maceler Aldrovandi, Christopher J Nicol

PLoS Pathog· November 2020

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Immunocytochemical Localization of Olfactory-signaling Molecules in Human and Rat Spermatozoa.
Yuliya Makeyeva, Christopher Nicol, William L Ledger, David K Ryugo

J Histochem Cytochem· July 2020

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Nanogold Neuroprotection in Human Neural Stem Cells Against Amyloid-beta-induced Mitochondrial Dysfunction.
Ming-Chang Chiang, Christopher J B Nicol, Yi-Chuan Cheng, Chiahui Yen, Chien-Hung Lin

Neuroscience· May 2020

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An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
Asish Dasgupta, Kuang-Hueih Chen, Danchen Wu, Victoria Hoskin, Jeffrey Mewburn, Christopher J B Nicol

FASEB J· April 2020

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