Publications by authors named "Christopher Nobles"

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Author Correction: Decade-long leukaemia remissions with persistence of CD4 CAR T cells.
J Joseph Melenhorst, Gregory M Chen, Meng Wang, David L Porter, Changya Chen, Christopher L Nobles

Nature· December 2022

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PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial.
Vivek Narayan, Julie S Barber-Rotenberg, In-Young Jung, Simon F Lacey, Andrew J Rech, Christopher L Nobles

Nat Med· April 2022

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Decade-long leukaemia remissions with persistence of CD4 CAR T cells.
J Joseph Melenhorst, Gregory M Chen, Meng Wang, David L Porter, Changya Chen, Christopher L Nobles

Nature· February 2022

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A more efficient CRISPR-Cas12a variant derived from MA2020.
Mai H Tran, Hajeung Park, Christopher L Nobles, Pabalu Karunadharma, Li Pan

Mol Ther Nucleic Acids· June 2021

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iGUIDE Method for CRISPR Off-Target Detection.
Christopher L Nobles

Methods Mol Biol· March 2021

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Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo.
Francesco R Simonetti, Hao Zhang, Garshasb P Soroosh, Jiayi Duan, Kyle Rhodehouse, Christopher L Nobles

J Clin Invest· February 2021

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Assessment of HIV-1 integration in tissues and subsets across infection stages.
Vincent H Wu, Christopher L Nobles, Leticia Kuri-Cervantes, Kevin McCormick, John K Everett

JCI Insight· October 2020

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Clonal tracking in gene therapy patients reveals a diversity of human hematopoietic differentiation programs.
Emmanuelle Six, Agathe Guilloux, Adeline Denis, Arnaud Lecoules, Alessandra Magnani, Christopher L Nobles

Blood· April 2020

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CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration.
Christopher L Nobles, Scott Sherrill-Mix, John K Everett, Shantan Reddy, Joseph A Fraietta

J Clin Invest· February 2020

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CRISPR-engineered T cells in patients with refractory cancer.
Edward A Stadtmauer, Joseph A Fraietta, Megan M Davis, Adam D Cohen, Kristy L Weber, Christopher L Nobles

Science· February 2020

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Impact of LEDGIN treatment during virus production on residual HIV-1 transcription.
Gerlinde Vansant, Lenard S Vranckx, Irena Zurnic, Dominique Van Looveren, Paulien Van de Velde, Christopher Nobles

Retrovirology· April 2019

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A quantitative approach for measuring the reservoir of latent HIV-1 proviruses.
Katherine M Bruner, Zheng Wang, Francesco R Simonetti, Alexandra M Bender, Kyungyoon J Kwon, Christopher Nobles

Nature· February 2019

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iGUIDE: an improved pipeline for analyzing CRISPR cleavage specificity.
Christopher L Nobles, Shantan Reddy, January Salas-McKee, Xiaojun Liu, Carl H June

Genome Biol· January 2019

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Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell.
Marco Ruella, Jun Xu, David M Barrett, Joseph A Fraietta, Tyler J Reich, Christopher L Nobles

Nat Med· October 2018

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Long-term remission despite clonal expansion of replication-competent HIV-1 isolates.
Rebecca T Veenhuis, Abena K Kwaa, Caroline C Garliss, Rachel Latanich, Maria Salgado, Christopher L Nobles

JCI Insight· September 2018

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Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells.
Joseph A Fraietta, Christopher L Nobles, Morgan A Sammons, Stefan Lundh, Shannon A Carty

Nature· June 2018

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INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions.
Charles C Berry, Christopher Nobles, Emmanuelle Six, Yinghua Wu, Nirav Malani

Mol Ther Methods Clin Dev· March 2017

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INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes.
Eric Sherman, Christopher Nobles, Charles C Berry, Emmanuelle Six, Yinghua Wu

Mol Ther Methods Clin Dev· March 2017

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A dual component heme biosensor that integrates heme transport and synthesis in bacteria.
Christopher L Nobles, Justin R Clark, Sabrina I Green, Anthony W Maresso

J Microbiol Methods· November 2015

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Combining random gene fission and rational gene fusion to discover near-infrared fluorescent protein fragments that report on protein-protein interactions.
Naresh Pandey, Christopher L Nobles, Lynn Zechiedrich, Anthony W Maresso, Jonathan J Silberg

ACS Synth Biol· May 2015

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A product of heme catabolism modulates bacterial function and survival.
Christopher L Nobles, Sabrina I Green, Anthony W Maresso

PLoS Pathog· February 2014

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Hal Is a Bacillus anthracis heme acquisition protein.
Miriam A Balderas, Christopher L Nobles, Erin S Honsa, Embriette R Alicki, Anthony W Maresso

J Bacteriol· October 2012

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The theft of host heme by Gram-positive pathogenic bacteria.
Christopher L Nobles, Anthony W Maresso

Metallomics· August 2011

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