Publications by authors named "Christopher Pfleger"

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The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET).
Hongli Zhang, Robert F Dierkes, Pablo Perez-Garcia, Elisa Costanzi, Jonas Dittrich, Christopher Pfleger

FEBS J· January 2024

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An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate.
Pablo Perez-Garcia, Jennifer Chow, Elisa Costanzi, Marno Gurschke, Jonas Dittrich, Christopher Pfleger

Commun Chem· September 2023

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Combining structural and coevolution information to unveil allosteric sites.
Giuseppina La Sala, Christopher Pfleger, Helena Käck, Lisa Wissler, Philip Nevin

Chem Sci· June 2023

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Enzyme adaptation to habitat thermal legacy shapes the thermal plasticity of marine microbiomes.
Ramona Marasco, Marco Fusi, Cristina Coscolín, Alan Barozzi, David Almendral, Christopher Pfleger

Nat Commun· February 2023

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Physiological, Biochemical, and Structural Bioinformatic Analysis of the Multiple Inositol Dehydrogenases from Corynebacterium glutamicum.
Paul Ramp, Christopher Pfleger, Jonas Dittrich, Christina Mack, Holger Gohlke

Microbiol Spectr· October 2022

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Uncoupling of Voltage- and Ligand-Induced Activation in HCN2 Channels by Glycine Inserts.
Sezin Yüksel, Michele Bonus, Tina Schwabe, Christopher Pfleger, Thomas Zimmer

Front Physiol· August 2022

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Allosteric signaling in C-linker and cyclic nucleotide-binding domain of HCN2 channels.
Christopher Pfleger, Jana Kusch, Mahesh Kondapuram, Tina Schwabe, Christian Sattler

Biophys J· March 2021

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Basal Histamine H Receptor Activation: Agonist Mimicry by the Diphenylalanine Motif.
David Wifling, Christopher Pfleger, Jonas Kaindl, Passainte Ibrahim, Ralf C Kling

Chemistry· November 2019

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Biallelic mutation of human encoding the taurine transporter TAUT is linked to early retinal degeneration.
Markus N Preising, Boris Görg, Christoph Friedburg, Natalia Qvartskhava, Birgit S Budde, Christopher Pfleger

FASEB J· October 2019

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Converging a Knowledge-Based Scoring Function: DrugScore.
Jonas Dittrich, Denis Schmidt, Christopher Pfleger, Holger Gohlke

J Chem Inf Model· January 2019

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Recognition motif and mechanism of ripening inhibitory peptides in plant hormone receptor ETR1.
Dalibor Milić, Markus Dick, Daniel Mulnaes, Christopher Pfleger, Anna Kinnen

Sci Rep· March 2018

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Ensemble- and Rigidity Theory-Based Perturbation Approach To Analyze Dynamic Allostery.
Christopher Pfleger, Alexander Minges, Markus Boehm, Christopher L McClendon, Rubben Torella

J Chem Theory Comput· December 2017

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Efficient and robust analysis of biomacromolecular flexibility using ensembles of network topologies based on fuzzy noncovalent constraints.
Christopher Pfleger, Holger Gohlke

Structure· October 2013

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CNA web server: rigidity theory-based thermal unfolding simulations of proteins for linking structure, (thermo-)stability, and function.
Dennis M Krüger, Prakash Chandra Rathi, Christopher Pfleger, Holger Gohlke

Nucleic Acids Res· July 2013

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Constraint Network Analysis (CNA): a Python software package for efficiently linking biomacromolecular structure, flexibility, (thermo-)stability, and function.
Christopher Pfleger, Prakash Chandra Rathi, Doris L Klein, Sebastian Radestock, Holger Gohlke

J Chem Inf Model· April 2013

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Global and local indices for characterizing biomolecular flexibility and rigidity.
Christopher Pfleger, Sebastian Radestock, Elena Schmidt, Holger Gohlke

J Comput Chem· January 2013

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Hot spots and transient pockets: predicting the determinants of small-molecule binding to a protein-protein interface.
Alexander Metz, Christopher Pfleger, Hannes Kopitz, Stefania Pfeiffer-Marek, Karl-Heinz Baringhaus

J Chem Inf Model· January 2012

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Pocket-space maps to identify novel binding-site conformations in proteins.
Ian R Craig, Christopher Pfleger, Holger Gohlke, Jonathan W Essex, Katrin Spiegel

J Chem Inf Model· October 2011

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