Publications by authors named "Christopher R Shaler"

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Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts.
Christopher R Shaler, Alexandra A Parco, Wael Elhenawy, Jasmeen Dourka, Jennifer Jury

Nat Commun· November 2021

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Low dietary fiber promotes enteric expansion of a Crohn's disease-associated pathobiont independent of obesity.
Trevor C Lau, Aline A Fiebig-Comyn, Christopher R Shaler, Joseph B McPhee, Brian K Coombes

Am J Physiol Endocrinol Metab· September 2021

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The Unique Lifestyle of Crohn's Disease-Associated Adherent-Invasive Escherichia coli.
Christopher R Shaler, Wael Elhenawy, Brian K Coombes

J Mol Biol· July 2019

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Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?
S M Mansour Haeryfar, Christopher R Shaler, Patrick T Rudak

Cancer Immunol Immunother· December 2018

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Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin.
Fatemeh Khadir, Christopher R Shaler, Ahmad Oryan, Patrick T Rudak, Delfina M Mazzuca

PLoS Negl Trop Dis· August 2018

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Mucosa-associated invariant T cells infiltrate hepatic metastases in patients with colorectal carcinoma but are rendered dysfunctional within and adjacent to tumor microenvironment.
Christopher R Shaler, Mauro E Tun-Abraham, Anton I Skaro, Khashayarsha Khazaie, Alexandra J Corbett

Cancer Immunol Immunother· December 2017

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PD-1 Blockade Promotes Epitope Spreading in Anticancer CD8 T Cell Responses by Preventing Fratricidal Death of Subdominant Clones To Relieve Immunodomination.
Arash Memarnejadian, Courtney E Meilleur, Christopher R Shaler, Khashayarsha Khazaie, Jack R Bennink

J Immunol· November 2017

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MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression.
Christopher R Shaler, Joshua Choi, Patrick T Rudak, Arash Memarnejadian, Peter A Szabo

PLoS Biol· June 2017

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The Future Liver Remnant in Patients Undergoing the Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy (ALPPS) Maintains the Immunological Components of a Healthy Organ.
Ram Venkatesh Anantha, Christopher Ryan Shaler, Courtney Erin Meilleur, Jeremy Parfitt, S M Mansour Haeryfar

Front Med (Lausanne)· August 2016

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Correction: Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway.
Varun C Anipindi, Puja Bagri, Kristy Roth, Sara E Dizzell, Philip V Nguyen, Christopher R Shaler

PLoS Pathog· June 2016

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Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway.
Varun C Anipindi, Puja Bagri, Kristy Roth, Sara E Dizzell, Philip V Nguyen, Christopher R Shaler

PLoS Pathog· May 2016

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CD1d- and MR1-Restricted T Cells in Sepsis.
Peter A Szabo, Ram V Anantha, Christopher R Shaler, John K McCormick, S M Mansour Haeryfar

Front Immunol· August 2015

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Restoration of innate immune activation accelerates Th1-cell priming and protection following pulmonary mycobacterial infection.
Rocky Lai, Mangalakumari Jeyanathan, Christopher R Shaler, Daniela Damjanovic, Amandeep Khera

Eur J Immunol· May 2014

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Continuous and discontinuous cigarette smoke exposure differentially affects protective Th1 immunity against pulmonary tuberculosis.
Christopher R Shaler, Carly N Horvath, Sarah McCormick, Mangalakumari Jeyanathan, Amandeep Khera

PLoS One· September 2013

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Understanding delayed T-cell priming, lung recruitment, and airway luminal T-cell responses in host defense against pulmonary tuberculosis.
Christopher R Shaler, Carly Horvath, Rocky Lai, Zhou Xing

Clin Dev Immunol· March 2013

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Within the Enemy's Camp: contribution of the granuloma to the dissemination, persistence and transmission of Mycobacterium tuberculosis.
Christopher R Shaler, Carly N Horvath, Mangalakumari Jeyanathan, Zhou Xing

Front Immunol· February 2013

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Control of pathogenic CD4 T cells and lethal immunopathology by signaling immunoadaptor DAP12 during influenza infection.
Sarah McCormick, Christopher R Shaler, Cherrie-Lee Small, Carly Horvath, Daniela Damjanovic

J Immunol· October 2011

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Pulmonary mycobacterial granuloma increased IL-10 production contributes to establishing a symbiotic host-microbe microenvironment.
Christopher R Shaler, Kapilan Kugathasan, Sarah McCormick, Daniela Damjanovic, Carly Horvath

Am J Pathol· April 2011

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Pulmonary mucosal dendritic cells in T-cell activation: implications for TB therapy.
Sarah McCormick, Christopher R Shaler, Zhou Xing

Expert Rev Respir Med· February 2011

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Respiratory mucosal immunization with adenovirus gene transfer vector induces helper CD4 T cell-independent protective immunity.
Jingyu Mu, Mangalakumari Jeyanathan, Christopher R Shaler, Carly Horvath, Daniela Damjanovic

J Gene Med· August 2010

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Murine airway luminal antituberculosis memory CD8 T cells by mucosal immunization are maintained via antigen-driven in situ proliferation, independent of peripheral T cell recruitment.
Mangalakumari Jeyanathan, Jingyu Mu, Sarah McCormick, Daniela Damjanovic, Cherrie-Lee Small, Christopher R Shaler

Am J Respir Crit Care Med· April 2010

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Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung.
Cherrie-Lee Small, Christopher R Shaler, Sarah McCormick, Mangalakumari Jeyanathan, Daniela Damjanovic

J Immunol· February 2010

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Mucosally delivered dendritic cells activate T cells independently of IL-12 and endogenous APCs.
Sarah McCormick, Michael Santosuosso, Cherrie-Lee Small, Christopher R Shaler, Xizhong Zhang

J Immunol· August 2008

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