Publications by authors named "Christopher Rowbottom"

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Optimization of dose and route of administration of the P-glycoprotein inhibitor, valspodar (PSC-833) and the P-glycoprotein and breast cancer resistance protein dual-inhibitor, elacridar (GF120918) as dual infusion in rats.
Christopher Rowbottom, Alicia Pietrasiewicz, Taras Tuczewycz, Richard Grater, Daniel Qiu

Pharmacol Res Perspect· April 2021

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Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach.
Vineet Kumar, Mengyue Yin, Kazuya Ishida, Laurent Salphati, Cornelis E C A Hop, Christopher Rowbottom

Drug Metab Dispos· February 2021

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Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood-Brain Barrier Measured by Quantitative Targeted Proteomics.
Sarah Billington, Laurent Salphati, Cornelis E C A Hop, Xiaoyan Chu, Raymond Evers, Christopher Rowbottom

Clin Pharmacol Ther· July 2019

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Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K.
Guangqing Xiao, Christopher Rowbottom, Carri Boiselle, Liang-Shang Gan

Pharm Res· June 2018

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Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics.
Sarah Billington, Adrian S Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, Christopher Rowbottom

Drug Metab Dispos· February 2018

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Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Christopher Rowbottom

Mol Pharmacol· March 2014

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Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase.
Dana Ferraris, Bridget Duvall, Greg Delahanty, Bipin Mistry, Jesse Alt, Christopher Rowbottom

J Med Chem· March 2014

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Pharmacokinetic characterization of a natural product-inspired novel MEK1 inhibitor E6201 in preclinical species.
Vipul Kumar, Edgar L Schuck, Robert D Pelletier, Nadia Farah, Krista B Condon, Christopher Rowbottom

Cancer Chemother Pharmacol· January 2012

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A high-performance liquid chromatography-tandem mass spectrometry method for the clinical combination study of carboplatin and anti-tumor agent eribulin mesylate (E7389) in human plasma.
Christopher Desjardins, Phil Saxton, Sharon X Lu, Xiaofang Li, Christopher Rowbottom

J Chromatogr B Analyt Technol Biomed Life Sci· November 2008

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