Publications by authors named "Christopher Rubino"

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Population pharmacokinetic analyses for telavancin using data from healthy subjects and patients with infections.
Scott A Van Wart, M Courtney Safir, Sujata M Bhavnani, Thomas P Lodise, Christopher M Rubino

Antimicrob Agents Chemother· July 2025

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Population pharmacokinetic analysis of tobramycin in serum and ELF using data from patients with pneumonia.
Scott A Van Wart, Michael Trang, M Courtney Safir, Andrew R Santulli, Christopher M Rubino

Antimicrob Agents Chemother· May 2025

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The distinctive pharmacokinetic profile of rezafungin, a long-acting echinocandin developed in the era of modern pharmacometrics.
David Andes, Roger J Brüggemann, Shawn Flanagan, Alexander J Lepak, Russell E Lewis, Christopher M Rubino

J Antimicrob Chemother· January 2025

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Population pharmacokinetic analyses for sulbactam-durlobactam using Phase 1, 2, and 3 data.
Anthony P Cammarata, M Courtney Safir, Michael Trang, Kajal B Larson, John P O'Donnell, Christopher M Rubino

Antimicrob Agents Chemother· January 2025

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Assessment of pharmacokinetics-pharmacodynamics to support omadacycline dosing regimens for the treatment of patients with acute bacterial skin and skin structure infections.
Sujata M Bhavnani, Jeffrey P Hammel, Elizabeth A Lakota, Kathryn Liolios, Michael Trang, Christopher M Rubino

Antimicrob Agents Chemother· September 2024

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Evaluation of Factors Predictive of Efficacy Among Patients With Complicated Urinary Tract Infection and/or Acute Pyelonephritis.
Sujata M Bhavnani, Jeffrey P Hammel, Christopher M Rubino, Angela K Talley, Paul B Eckburg

Open Forum Infect Dis· September 2024

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Impact of antibiotic pharmacokinetics in urine on recurrent bacteriuria following treatment of complicated urinary tract infections.
David Melnick, Angela K Talley, Vipul K Gupta, Ian A Critchley, Paul B Eckburg, Christopher M Rubino

Antimicrob Agents Chemother· October 2023

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A Phase 1 First-in-Human Single-Ascending-Dose Trial With ESB1609, a Selective Agonist to the Sphingosine-1-Phosphate Receptor 5.
Nicholas P France, Christopher Rubino, M Courtney Safir, Mari Maurer, Tram Duong

Clin Pharmacol Drug Dev· June 2023

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Pharmacokinetic-Pharmacodynamic Target Attainment Analyses Evaluating Omadacycline Dosing Regimens for the Treatment of Patients with Community-Acquired Bacterial Pneumonia Arising from Streptococcus pneumoniae and Haemophilus influenzae.
Sujata M Bhavnani, Jeffrey P Hammel, Elizabeth A Lakota, Michael Trang, Justin C Bader, Christopher M Rubino

Antimicrob Agents Chemother· April 2023

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Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers.
Pete Schmidt, Kristin Narayan, Yong Li, Chengzi I Kaku, Michael E Brown, Christopher M Rubino

Sci Transl Med· March 2023

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Pharmacokinetic/Pharmacodynamic Evaluation of the Dipeptidyl Peptidase 1 Inhibitor Brensocatib for Non-cystic Fibrosis Bronchiectasis.
James D Chalmers, Helen Usansky, Christopher M Rubino, Ariel Teper, Carlos Fernandez

Clin Pharmacokinet· October 2022

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Pharmacokinetics and Safety of Ceftobiprole in Pediatric Patients.
Christopher M Rubino, Mark Polak, Sebastian Schröpf, Hans Georg Münch, Anne Smits

Pediatr Infect Dis J· November 2021

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Model-Based Approach for Optimizing Ceftobiprole Dosage in Pediatric Patients.
Christopher M Rubino, Anthony P Cammarata, Anne Smits, Sebastian Schröpf, Mark Polak

Antimicrob Agents Chemother· October 2021

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Population Pharmacokinetics of Rezafungin in Patients with Fungal Infections.
Christopher M Rubino, Shawn Flanagan

Antimicrob Agents Chemother· October 2021

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Correction to: Population Pharmacokinetic Evaluation of Amikacin Liposome Inhalation Suspension in Patients with Treatment‑Refractory Nontuberculous Mycobacterial Lung Disease.
Christopher M Rubino, Nikolas J Onufrak, Jakko van Ingen, David E Griffith, Sujata M Bhavnani

Eur J Drug Metab Pharmacokinet· July 2021

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Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia.
Helen Shiells, Bjoern O Schelter, Peter Bentham, Thomas C Baddeley, Christopher M Rubino

J Alzheimers Dis· May 2021

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Pharmacokinetics and Optimal Dose Selection of Cefazolin for Surgical Prophylaxis of Pediatric Patients.
Michael L Schmitz, Christopher M Rubino, Nikolas J Onufrak, Diana Valencia Martinez, Diane Licursi

J Clin Pharmacol· May 2021

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Population Pharmacokinetic Evaluation of Amikacin Liposome Inhalation Suspension in Patients with Treatment-Refractory Nontuberculous Mycobacterial Lung Disease.
Christopher M Rubino, Nikolas J Onufrak, Jakko van Ingen, David E Griffith, Sujata M Bhavnani

Eur J Drug Metab Pharmacokinet· March 2021

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Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer's Disease.
Bjoern O Schelter, Helen Shiells, Thomas C Baddeley, Christopher M Rubino, Harish Ganesan

J Alzheimers Dis· November 2020

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Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Support Dose Selection for ME1100, an Arbekacin Inhalation Solution.
Sujata M Bhavnani, Jeffrey P Hammel, Elizabeth A Lakota, M Courtney Safir, Brian D VanScoy, Christopher M Rubino

Antimicrob Agents Chemother· September 2020

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Antibacterial Drug Development: A New Approach Is Needed for the Field to Survive and Thrive.
M Courtney Safir, Sujata M Bhavnani, Christine M Slover, Paul G Ambrose, Christopher M Rubino

Antibiotics (Basel)· July 2020

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Population Pharmacokinetic Analyses for Omadacycline Using Phase 1 and 3 Data.
Elizabeth A Lakota, Scott A Van Wart, Michael Trang, Evan Tzanis, Sujata M Bhavnani, Christopher M Rubino

Antimicrob Agents Chemother· June 2020

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Population Pharmacokinetic Analyses for Arbekacin after Administration of ME1100 Inhalation Solution.
Elizabeth A Lakota, Nobuo Sato, Tomokazu Koresawa, Kenichiro Kondo, Sujata M Bhavnani, Christopher M Rubino

Antimicrob Agents Chemother· August 2019

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Pharmacokinetic/pharmacodynamic target attainment analyses to support intravenous and oral lefamulin dose selection for the treatment of patients with community-acquired bacterial pneumonia.
Sujata M Bhavnani, Li Zhang, Jeffrey P Hammel, Christopher M Rubino, Justin C Bader

J Antimicrob Chemother· April 2019

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Prediction of lefamulin epithelial lining fluid penetration after intravenous and oral administration using Phase 1 data and population pharmacokinetics methods.
Li Zhang, Wolfgang W Wicha, Sujata M Bhavnani, Christopher M Rubino

J Antimicrob Chemother· April 2019

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